Macromolecular specializations that mediate lateral interactions between microfilaments and the membrane at focal contacts
1992 ◽
Vol 50
(1)
◽
pp. 724-725
Keyword(s):
Focal contacts are membrane specializations of cultured cells where stress fibers terminate and where the cell is most closely applied to the substrate. The organization of this cytoskeletal-membrane-extracellular matrix assembly has been well characterized. Immunofluorescence microscopy has shown that two focal contact-specific proteins, vinculin and talin, colocalize with microfilaments for several microns before the stress fiber terminates. This result raises the question of whether microfilament-membrane interactions are limited to the ends of microfilaments, or if lateral interactions also occur. We addressed this question by examining the cytoplasmic surface of isolated focal contacts in detail.
1999 ◽
Vol 10
(5)
◽
pp. 1521-1536
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1984 ◽
Vol 99
(6)
◽
pp. 2268-2278
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1982 ◽
Vol 93
(3)
◽
pp. 804-811
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Keyword(s):
1990 ◽
Vol 111
(6)
◽
pp. 2475-2485
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Keyword(s):
1992 ◽
Vol 117
(5)
◽
pp. 1007-1022
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Keyword(s):
1991 ◽
Vol 114
(5)
◽
pp. 1089-1100
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1982 ◽
Vol 92
(2)
◽
pp. 398-408
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Keyword(s):
2017 ◽
Vol 43
(5)
◽
pp. 1777-1789
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Keyword(s):
1998 ◽
Vol 142
(5)
◽
pp. 1357-1369
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Keyword(s):