Rate and significance of hypomanic switches in unipolar melancholic depression

1993 ◽  
Vol 8 (3) ◽  
pp. 125-129 ◽  
Author(s):  
JM Menchon ◽  
C Gasto ◽  
J Vallejo ◽  
R Catalan ◽  
A Otero ◽  
...  

SummaryOne hundred and sixteen patients with RDC unipolar recurrent depressive disorder, melancholic subtype, were treated with imipramine or phenelzine and followed-up for six months. None of the patients had a first-degree relative with bipolar I disorder. Twenty-six patients (22.4%) presented an hypomanic episode (‘hypomanic group’). This group of patients, when depressed, had a significantly lower age of onset of the disorder and higher response to antidepressant therapy than patients who did not present an hypomanic episode. Significantly more patients (88%) of the ‘hypomanic group’ had at least one first-degree relative with a history of major depressive disorder. These patients displayed some of the typical features of bipolar II disorder. Overall results support the continuum in clinical phenomena between unipolar and bipolar disorders.

2016 ◽  
Vol 18 (1) ◽  
pp. 63-70 ◽  
Author(s):  
Hui Hua Chang ◽  
Tzu-Yun Wang ◽  
I Hui Lee ◽  
Sheng-Yu Lee ◽  
Kao Chin Chen ◽  
...  

Author(s):  
Zella Moore ◽  
Jamie Leboff ◽  
Kehana Bonagura

Major depressive disorder, dysthymia, and bipolar disorder are very common diagnoses seen among athletes, and they are serious conditions that can be debilitating if not properly addressed. These disorders warrant careful attention because they can adversely affect multiple domains of an athlete’s life, including athletic motivation, performance outcomes, interpersonal well-being, health, and overall daily functioning. Key foci include the prevalence of, clinical characteristics of, causes of, and risk factors for major depressive disorder, persistent depressive disorder/dysthymia, bipolar I disorder, and bipolar II disorder. Sport psychologists should integrate such important information into their overall case conceptualization and decision-making processes to ensure that athletes and performers at risk for, or struggling with, such mental health concerns receive the most effective, efficient, and timely care possible.


2020 ◽  
Vol 28 (3) ◽  
pp. 335-338
Author(s):  
Gordon Parker

Objective: The objective of this study is to report on the degree of consensus in experts’ recommendations for managing bipolar II disorder. Methods: Eighteen international clinician researchers with expertise in managing bipolar disorders were provided with 14 questions addressing nuances in managing those with a bipolar II disorder. Results: To all questions, the independently derived recommended strategies demonstrated distinct divergence. Conclusion: The lack of consensus in management recommendations is likely to reflect the disorder being relatively recently formalised, the lack of condition-specific randomised controlled trial data and the nature of psychiatric practice.


2008 ◽  
Vol 69 (10) ◽  
pp. 1589-1601 ◽  
Author(s):  
David J. Bond ◽  
Melissa M. Noronha ◽  
Marcia Kauer-Sant'Anna ◽  
Raymond W. Lam ◽  
Lakshmi N. Yatham

PLoS ONE ◽  
2020 ◽  
Vol 15 (5) ◽  
pp. e0232459
Author(s):  
Chihiro Morishita ◽  
Rie Kameyama ◽  
Hiroyuki Toda ◽  
Jiro Masuya ◽  
Masahiko Ichiki ◽  
...  

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
V. Adomaitiene ◽  
A. Kunigeliene ◽  
K. Dambrauskiene ◽  
V. Danileviciute

Introduction:Bipolar disorder is one of the most important psychiatric diseases. This is a lifelong illness which increases disability, bad social, employment, and functional outcomes. Bipolar disorder causes dramatic mood swings - from overly “high” and irritable to sad and hopeless, often with periods of normal mood between. Bipolar I disorder is characterized by a history of at least one manic episode, with or without depressive symptoms. Bipolar II disorder is characterized by the presence of both depressive symptoms and a less severe form of mania.Objective:To review diagnostic and treatment situation of bipolar affective disorders in Lithuania.Method:A review of bipolar affective disorders in Lithuania: the prevalence of bipolar disorders, the differences between genders, the clinical features between genders.Results:Studies have suggested, that the prevalence of bipolar disorder in Lithuania is 1 % of population. The rates of bipolar disorder: in 2003 was 1131 cases, in 2004 - 1133 cases, in 2005 - 1147 cases, in 2006 - 1255 cases, in 2007 - 1257 cases. Distribution of bipolar disorders between males and females: males - 35,88 %, females - 64,12 %.Conclusion:The rates of Bipolar I disorder are equal between female and male population, but bipolar II disorder is more frequent in female population (bipolar depression, mixed manic disorder). Bipolar disorder with alcohol and drug abuse are very common among male population. Bipolar disorders are very common with somatic disease (thyroid disease, migraine, obesity of medication), anxiety disorders are more frequent in female population.


2003 ◽  
Vol 60 (3) ◽  
pp. 261 ◽  
Author(s):  
Lewis L. Judd ◽  
Hagop S. Akiskal ◽  
Pamela J. Schettler ◽  
William Coryell ◽  
Jean Endicott ◽  
...  

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