scholarly journals Risk factors for toxoplasmosis in pregnant women in Kent, United Kingdom

2005 ◽  
Vol 133 (3) ◽  
pp. 475-483 ◽  
Author(s):  
J. Q. NASH ◽  
S. CHISSEL ◽  
J. JONES ◽  
F. WARBURTON ◽  
N. Q. VERLANDER

The aim of this study was to establish the relative importance of various risk factors for toxoplasmosis in a United Kingdom antenatal population. Toxoplasma immune status was determined by an immunoassay and linked to a questionnaire exploring dietary and environmental exposure to toxoplasmosis. The overall seroprevalence found was 9·1% (172/1897). A significantly higher seroprevalence was associated with rural location of the childhood home, childhood home in Europe excluding the United Kingdom, feeding a dog raw meat and increased age. A non-significant higher prevalence of toxoplasmosis was observed in women who had lived with a cat or kitten as a child. In contrast to recent European studies only weak associations between diet and toxoplasmosis were found. Gardening activity was not associated with seropositivity but a non-significant lower seroprevalence was seen in gardeners who always wore gloves. This study confirms that toxoplasma prevalence in the United Kingdom has continued to decline since the 1960s. The increasing seroprevalence with age found in this study, highlights the continuing need to educate women of childbearing age about the risk factors for toxoplasmosis.

BMJ ◽  
1988 ◽  
Vol 297 (6659) ◽  
pp. 1301-1304 ◽  
Author(s):  
N. D. Noah ◽  
S. E. Fowle

2015 ◽  
Vol 5 (1) ◽  
pp. 12-19 ◽  
Author(s):  
Laura Goodwin ◽  
Billie Hunter ◽  
Aled Jones

The United Kingdom has seen a substantial rise in immigration over the past 10 years. This new population has a high percentage of women of childbearing age (Office for National Statistics, 2012b), consequently placing an increased demand on U.K. maternity services. Previous research suggests lower satisfaction and worse maternity outcomes for migrant and minority ethnic women both in the United Kingdom and abroad. Most papers exploring ethnic health inequalities have centered on causal factors such as differences in socioeconomic status and host country language ability. Health care policies to tackle inequalities in the United Kingdom, based on these assumptions, have had limited success. Consequently, alternative causal factors need to be explored. This article discusses ethnic inequalities in maternity outcomes in the United Kingdom and proposes that research exploring the client–provider relationship in migrant women’s maternity care could provide important new insights.


2021 ◽  
Vol 49 (5) ◽  
pp. 030006052110155
Author(s):  
Brian W Johnston ◽  
David Perry ◽  
Martyn Habgood ◽  
Miland Joshi ◽  
Anton Krige

Objective Augmented renal clearance (ARC) is associated with sub-therapeutic antibiotic, anti-epileptic, and anticoagulant serum concentrations leading to adverse patient outcomes. We aimed to describe the prevalence and associated risk factors for ARC development in a large, single-centre cohort in the United Kingdom. Methods We conducted a retrospective observational study of critically unwell patients admitted to intensive care between 2014 and 2016. Urinary creatinine clearance was used to determine the ARC prevalence during the first 7 days of admission. Repeated measures logistic regression was used to determine risk factors for ARC development. Results The ARC prevalence was 47.0% (95% confidence interval [95%CI]: 44.3%–49.7%). Age, sex, Acute Physiology and Chronic Health Evaluation (APACHE) II score, and sepsis diagnosis were significantly associated with ARC. ARC was more prevalent in younger vs. older (odds ratio [OR] 0.95 [95%CI: 0.94–0.96]), male vs. female (OR 0.32 [95%CI: 0.26–0.40]) patients with lower vs. higher APACHE II scores (OR 0.94 [95%CI: 0.92–0.96]). Conclusions This patient group probably remains unknown to many clinicians because measuring urinary creatinine clearance is not usually indicated in this group. Clinicians should be aware of the ARC risk in this group and consider measurement of urinary creatinine clearance.


2003 ◽  
Vol 57 (12) ◽  
pp. 1627-1632 ◽  
Author(s):  
R D Semba ◽  
S de Pee ◽  
D Panagides ◽  
O Poly ◽  
M W Bloem

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