The health and economic burden of chickenpox and herpes zoster in Belgium

2012 ◽  
Vol 140 (11) ◽  
pp. 2096-2109 ◽  
Author(s):  
J. BILCKE ◽  
B. OGUNJIMI ◽  
C. MARAIS ◽  
F. DE SMET ◽  
M. CALLENS ◽  
...  
Keyword(s):  
Herpes Zoster ◽  
General Practitioner ◽  
Direct Medical Cost ◽  
Medical Cost ◽  
Quality Adjusted Life Years ◽  
Varicella Zoster ◽  
Hospitalization Rates ◽  
Life Years ◽  
Life Years Lost ◽  
Quality Adjusted Life

SUMMARYVaricella-zoster virus causes chickenpox (CP) and after reactivation herpes zoster (HZ). Vaccines are available against both diseases warranting an assessment of the pre-vaccination burden of disease. We collected data from relevant Belgian databases and performed five surveys of CP and HZ patients. The rates at which a general practitioner is visited at least once for CP and HZ are 346 and 378/100 000 person-years, respectively. The average CP and HZ hospitalization rates are 5·3 and 14·2/100 000 person-years respectively. The direct medical cost for HZ is about twice as large as the direct medical cost for CP. The quality-adjusted life years lost for ambulatory CP patients consulting a physician is more than double that of those not consulting a physician (0·010vs. 0·004). In conclusion, both diseases cause a substantial burden in Belgium.

Quality-adjusted life years lost to arthritis: Effects of gender, race, and social class

1996 ◽  
Vol 9 (6) ◽  
pp. 473-482 ◽  
Author(s):  
Robert M. Kaplan ◽  
John E. Alcaraz ◽  
John P. Anderson ◽  
Michael Weisman
Keyword(s):  
Social Class ◽  
Quality Adjusted Life Years ◽  
Life Years ◽  
Life Years Lost ◽  
Quality Adjusted Life

scholarly journals The Characteristics of Influenza-Like Illness Management in Japan

2020 ◽  
Author(s):  
Shinya Tsuzuki ◽  
Keisuke Yoshihara
Keyword(s):  
Diagnostic Test ◽  
Online Survey ◽  
Quality Adjusted Life Years ◽  
Duration Of Symptoms ◽  
Healthcare Facilities ◽  
Influenza Like Illness ◽  
Life Years ◽  
Life Years Lost ◽  
Absence From Work ◽  
Quality Adjusted Life

Abstract Background: This study aimed to make a quantitative assessment of the management of influenza-like illnesses in Japanese healthcare settings. Methods: We analysed participants’ healthcare-seeking behaviour and physicians’ practice in January 2019 using an online survey of 200 households in Japan. Quality of life score, quality-adjusted life years lost, the duration of symptoms, and the duration of absence from work were compared between influenza group and influenza-like illness group with one-to-one propensity score matching. Missing data were imputed using multiple imputation. Results: In total, 261 of the 600 (43.5%) participants had at least one episode of influenza-like illness during January 2019. Of these, 194 (75.5%) visited healthcare facilities, 167 (86.1%) within 2 days of onset of symptoms. A total of 169 out of 191 (88.5%) received a rapid influenza diagnostic test and 101 were diagnosed with influenza, of whom 95.0% were treated with antivirals. The median quality-adjusted life-years lost was 0.0055 (interquartile range, IQR 0.0040–0.0072) and median absence from work for a single episode of influenza-like illness was 2 days (IQR 1–5 days). Conclusions: In Japan, most people with influenza-like illnesses visit healthcare facilities soon after symptoms first occur and receive a diagnostic test. Those with influenza are usually treated with antivirals. Absence from work was longer for influenza than other similar illnesses.

scholarly journals The Characteristics of Influenza-Like Illness Management in Japan

2019 ◽  
Author(s):  
Shinya Tsuzuki ◽  
Keisuke Yoshihara
Keyword(s):  
Diagnostic Test ◽  
Online Survey ◽  
Quality Adjusted Life Years ◽  
Duration Of Symptoms ◽  
Healthcare Facilities ◽  
Influenza Like Illness ◽  
Life Years ◽  
Life Years Lost ◽  
Absence From Work ◽  
Quality Adjusted Life

Abstract Background: This study aimed to make a quantitative assessment of the management of influenza-like illnesses in Japanese healthcare settings. Methods: We analysed participants’ healthcare-seeking behaviour and physicians’ practice in January 2019 using an online survey of 200 households in Japan. Quality of life score, quality-adjusted life years lost, the duration of symptoms, and the duration of absence from work were compared between influenza group and influenza-like illness group with one-to-one propensity score matching. Missing data were imputed using multiple imputation. Results: In total, 261 of the 600 (43.5%) participants had at least one episode of influenza-like illness during January 2019. Of these, 194 (75.5%) visited healthcare facilities, 167 (86.1%) within 2 days of onset of symptoms. A total of 169 out of 191 (88.5%) received a rapid influenza diagnostic test and 101 were diagnosed with influenza, of whom 92.2% were treated with antivirals. The median quality-adjusted life-years lost was 0.0055 (interquartile range, IQR 0.0040–0.0072) and median absence from work for a single episode of influenza-like illness was 2 days (IQR 1–5 days). Conclusions: In Japan, most people with influenza-like illnesses visit healthcare facilities soon after symptoms first occur and receive a diagnostic test. Those with influenza are usually treated with antivirals. Absence from work was longer for influenza than other similar illnesses.

The Danger of Applying Group-level Utilities in Decision Analyses of the Treatment of Localized Prostate Cancer in Individual Patients

1998 ◽  
Vol 18 (4) ◽  
pp. 376-380 ◽  
Author(s):  
Mark E. Cowen ◽  
Brian J. Miles ◽  
Daniel F. Cahill ◽  
R. Brian Giesler ◽  
J. Robert Beck ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Decision Analysis ◽  
Localized Prostate Cancer ◽  
Group Level ◽  
Quality Adjusted Life Years ◽  
Individual Level ◽  
Life Years ◽  
Life Years Lost ◽  
The Individual ◽  
Quality Adjusted Life

The optimal management strategy for men who have localized prostate cancer remains controversial. This study examines the extent to which suggested treatment based on the perspective of a group or society agrees with that derived from individual patients' preferences. A previously published decision analysis for localized prostate cancer was used to suggest the treatment that maximized quality-adjusted life expectancy. Two treatment recommendations were obtained for each patient: the first (group-level) was derived using the mean utilities of the cohort; the second (individual-level) used his own set of utilities. Group-level utilities misrepresented 25-48% of individuals' pref erences depending on the grade of tumor modeled. The best kappa measure achieved between group and individual preferences was 0.11. The average quality-adjusted life years lost due to misrepresentation of preference was as high as 1.7 quality-adjusted life years. Use of aggregated utilities in a group-level decision analysis can ignore the substantial variability at the individual level. Caution is needed when applying a group- level recommendation to the treatment of localized prostate cancer in an individual patient. Key words: decision analysis; utility assessment; prostate cancer; patient pref erences. (Med Decis Making 1998;18:376-380)

scholarly journals Quality‐Adjusted Life‐Years Lost Due to Physical Inactivity in a US Population With Osteoarthritis

2020 ◽  
Vol 72 (10) ◽  
pp. 1349-1357 ◽  
Author(s):  
Elena Losina ◽  
Genevieve S. Silva ◽  
Karen C. Smith ◽  
Jamie E. Collins ◽  
David J. Hunter ◽  
...  
Keyword(s):  
Physical Inactivity ◽  
Quality Adjusted Life Years ◽  
Life Years ◽  
Life Years Lost ◽  
Quality Adjusted Life
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