scholarly journals The Characteristics of Influenza-Like Illness Management in Japan

2019 ◽  
Author(s):  
Shinya Tsuzuki ◽  
Keisuke Yoshihara

Abstract Background: This study aimed to make a quantitative assessment of the management of influenza-like illnesses in Japanese healthcare settings. Methods: We analysed participants’ healthcare-seeking behaviour and physicians’ practice in January 2019 using an online survey of 200 households in Japan. Quality of life score, quality-adjusted life years lost, the duration of symptoms, and the duration of absence from work were compared between influenza group and influenza-like illness group with one-to-one propensity score matching. Missing data were imputed using multiple imputation. Results: In total, 261 of the 600 (43.5%) participants had at least one episode of influenza-like illness during January 2019. Of these, 194 (75.5%) visited healthcare facilities, 167 (86.1%) within 2 days of onset of symptoms. A total of 169 out of 191 (88.5%) received a rapid influenza diagnostic test and 101 were diagnosed with influenza, of whom 92.2% were treated with antivirals. The median quality-adjusted life-years lost was 0.0055 (interquartile range, IQR 0.0040–0.0072) and median absence from work for a single episode of influenza-like illness was 2 days (IQR 1–5 days). Conclusions: In Japan, most people with influenza-like illnesses visit healthcare facilities soon after symptoms first occur and receive a diagnostic test. Those with influenza are usually treated with antivirals. Absence from work was longer for influenza than other similar illnesses.

2020 ◽  
Author(s):  
Shinya Tsuzuki ◽  
Keisuke Yoshihara

Abstract Background: This study aimed to make a quantitative assessment of the management of influenza-like illnesses in Japanese healthcare settings. Methods: We analysed participants’ healthcare-seeking behaviour and physicians’ practice in January 2019 using an online survey of 200 households in Japan. Quality of life score, quality-adjusted life years lost, the duration of symptoms, and the duration of absence from work were compared between influenza group and influenza-like illness group with one-to-one propensity score matching. Missing data were imputed using multiple imputation. Results: In total, 261 of the 600 (43.5%) participants had at least one episode of influenza-like illness during January 2019. Of these, 194 (75.5%) visited healthcare facilities, 167 (86.1%) within 2 days of onset of symptoms. A total of 169 out of 191 (88.5%) received a rapid influenza diagnostic test and 101 were diagnosed with influenza, of whom 95.0% were treated with antivirals. The median quality-adjusted life-years lost was 0.0055 (interquartile range, IQR 0.0040–0.0072) and median absence from work for a single episode of influenza-like illness was 2 days (IQR 1–5 days). Conclusions: In Japan, most people with influenza-like illnesses visit healthcare facilities soon after symptoms first occur and receive a diagnostic test. Those with influenza are usually treated with antivirals. Absence from work was longer for influenza than other similar illnesses.


2012 ◽  
Vol 140 (11) ◽  
pp. 2096-2109 ◽  
Author(s):  
J. BILCKE ◽  
B. OGUNJIMI ◽  
C. MARAIS ◽  
F. DE SMET ◽  
M. CALLENS ◽  
...  

SUMMARYVaricella-zoster virus causes chickenpox (CP) and after reactivation herpes zoster (HZ). Vaccines are available against both diseases warranting an assessment of the pre-vaccination burden of disease. We collected data from relevant Belgian databases and performed five surveys of CP and HZ patients. The rates at which a general practitioner is visited at least once for CP and HZ are 346 and 378/100 000 person-years, respectively. The average CP and HZ hospitalization rates are 5·3 and 14·2/100 000 person-years respectively. The direct medical cost for HZ is about twice as large as the direct medical cost for CP. The quality-adjusted life years lost for ambulatory CP patients consulting a physician is more than double that of those not consulting a physician (0·010vs. 0·004). In conclusion, both diseases cause a substantial burden in Belgium.


1996 ◽  
Vol 9 (6) ◽  
pp. 473-482 ◽  
Author(s):  
Robert M. Kaplan ◽  
John E. Alcaraz ◽  
John P. Anderson ◽  
Michael Weisman

2021 ◽  
Author(s):  
Robin Bruyndonckx ◽  
Joke Bilcke ◽  
Alike W. van der Velden ◽  
Xiao Li ◽  
Niel Hens ◽  
...  

1998 ◽  
Vol 18 (4) ◽  
pp. 376-380 ◽  
Author(s):  
Mark E. Cowen ◽  
Brian J. Miles ◽  
Daniel F. Cahill ◽  
R. Brian Giesler ◽  
J. Robert Beck ◽  
...  

The optimal management strategy for men who have localized prostate cancer remains controversial. This study examines the extent to which suggested treatment based on the perspective of a group or society agrees with that derived from individual patients' preferences. A previously published decision analysis for localized prostate cancer was used to suggest the treatment that maximized quality-adjusted life expectancy. Two treatment recommendations were obtained for each patient: the first (group-level) was derived using the mean utilities of the cohort; the second (individual-level) used his own set of utilities. Group-level utilities misrepresented 25-48% of individuals' pref erences depending on the grade of tumor modeled. The best kappa measure achieved between group and individual preferences was 0.11. The average quality-adjusted life years lost due to misrepresentation of preference was as high as 1.7 quality-adjusted life years. Use of aggregated utilities in a group-level decision analysis can ignore the substantial variability at the individual level. Caution is needed when applying a group- level recommendation to the treatment of localized prostate cancer in an individual patient. Key words: decision analysis; utility assessment; prostate cancer; patient pref erences. (Med Decis Making 1998;18:376-380)


2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S923-S924 ◽  
Author(s):  
Shinya Tsuzuki ◽  
Keisuke Yoshihara

Abstract Background Influenza-like illness (ILI) is a common disease that imposes a severe disease burden at the population level. ILI management is important in view of population health, and Japan’s management is distinct from that in other countries, especially regarding diagnosis and treatment of seasonal influenza. This study’s main objective was to quantitatively assess ILI management in Japanese healthcare settings. Methods In February 2019, we conducted an online survey of 600 participants in 200 households concerning ILI and its management in Japan. Respondents reported ILI episodes they and/or their family members experienced during January 2019. The 12-Item Short-Form Health Survey, Version 2 (SF-12v2) was included in the questionnaire to estimate quality of life (QOL) lost through ILI, and quality-adjusted life years (QALYs) lost in that way. We analyzed participants’ healthcare-seeking behavior to clarify the characteristics of Japanese ambulatory care for ILI. Results Of the participants, 261 of 600 (43.5%) reported at least one episode of ILI during January 2019. Of these, 194 (75.5%) visited healthcare facilities and 167 (86.1%) visited facilities within 2 days of symptom onset. A rapid influenza diagnostic test (RIDT) was given to 169 of 191 (88.5%) and 101 patients received a diagnosis of influenza, rather than ILI. Antivirals were used to treat 92.2% of the influenza cases. The median values of QOL and QALYs lost during a symptomatic period of ILI were 0.67 (interquartile range: 0.60–0.79) and 0.0055 (interquartile range: 0.0040–0.0072), respectively. Conclusion In Japan, most ILI patients visit healthcare facilities in the early phase of symptoms, and most physicians examine them using the RIDT. Most laboratory-diagnosed influenza cases are treated using antivirals. Future work should examine the relation between this early diagnosis and treatment practice, and the duration and severity of ILI symptoms. Disclosures All authors: No reported disclosures.


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