The significance of manic syndromes in old age

2001 ◽  
Vol 11 (2) ◽  
pp. 159-165
Author(s):  
Kenneth I Shulman
Keyword(s):  
Old Age ◽  
Clinical Course ◽  
Co Morbidity ◽  
Brain Localization

IntroductionSince the last review of this topic in this journal, there has been a focusing of efforts to clarify the classification of manic syndromes and their neurobiologic basis. This has involved proposals for more refined subtypes, as well as descriptions of brain localization and co-morbidity. Our understanding of the epidemiology, genetics, clinical course and treatment of manic syndromes has not substantially altered over the last decade.

Primary tracheal leiomyosarcoma

2000 ◽  
Vol 114 (1) ◽  
pp. 64-66
Author(s):  
Kathrin Reichert ◽  
Kai Helling ◽  
Hans Dietrich Menssen ◽  
Alejandra Perez-Canto ◽  
Hans Scherer
Keyword(s):  
Complete Remission ◽  
Female Patient ◽  
Clinical Course ◽  
Diagnostic Approach ◽  
Pathological Classification ◽  
Therapeutic Procedures

We present the clinical course of a 56-year-old female patient with a primary tracheal leiomyosarcoma. The diagnostic approach and pathological classification of this seldom described tumour remains extremely difficult. We discuss the symptoms as well as the diagnostic and therapeutic procedures, including multimodal chemotherapy with organ-preserving surgery leading to complete remission.

To the study of early dementia

1902 ◽  
Vol 2 (9) ◽  
pp. 480-481
Author(s):  
V. Serbskiy
Keyword(s):  
Clinical Course ◽  
Mental Illnesses ◽  
Dementia Praecox ◽  
The Third ◽  
Current State ◽  
Early Dementia

In the first part of his article, the author examines the current state of the issue of secondary dementia and proves that a group of psychoses, known under the name secondary dementia, should be left in the classification of mental illnesses. The second part is devoted to the analysis of Krpelin's scholarship on dementia praecox, and the author fundamentally disagrees with many of the provisions of the latter. In the third part, the ethiology, clinical course and recognition of premature dementia are analyzed.

scholarly journals The Clinical Course and Prognostic Problems of Youth Depressions with Attenuated Schizophrenic Symptoms

2021 ◽  
pp. 42-52
Author(s):  
V. G. Kaleda ◽  
M. A. Omelchenko
Keyword(s):  
Depressive Episode ◽  
Functional Outcomes ◽  
Negative Symptoms ◽  
Clinical Course ◽  
Control Group ◽  
Youth Depression ◽  
Early Markers ◽  
Spectrum Disorders

Objective Clinical and follow-up verification of Attenuated Schizophrenic Symptoms (ASS) in the first youth depressive episode as early markers of the schizophrenic process, establishing further variants of the course of the disorder and its outcomes.Materials and methods. 124 young inpatients (averaged age 19,6±2,3 years) with the first depressive episode with ASS were examined. The control group consisted of 27 patients with youth depression without ASS. All patients have been tracked for at least five years. The average follow-up period was 7,1±1,6 years. The HDRS, SOPS, SANS and PSP scales were used to assess the symptomatic and functional outcomes. Statistical analysis was carried out using STATISTICA 12.Results. The typological classification of youth depressions (ASD) with ASS has been developed with the identification of three main types: (1) with attenuated positive symptoms (APS), (2) with attenuated negative symptoms (ANS), and (3) with attenuated symptoms of disorganization. Youth depression with ASS, compared to the control group, is more likely to move into chronic forms, has reliably worse functional and symptomatic outcomes, and is more associated with the diagnosis of schizophrenic spectrum disorders at five years follow-up.Conclusion. Attenuated schizophrenic symptoms in the structure of youth depressions have high affinity to each other, indicating a common pathogenic mechanism of their formation, and also have predicate value as risk factors for schizophrenia.

Clinical Course of Different Types of Immune Reactions following Keratoplasty

2021 ◽  
Author(s):  
Philip Keye ◽  
Thabo Lapp ◽  
Daniel Böhringer ◽  
Sonja Heinzelmann ◽  
Philip Maier ◽  
...  
Keyword(s):  
Clinical Course ◽  
Corneal Graft ◽  
Long Term Outcomes ◽  
Immune Mediated ◽  
Corneal Graft Rejection ◽  
Different Types ◽  
Lost To Follow Up

Abstract Background Immune-mediated corneal graft rejection (IR) is a leading cause of corneal graft failure. The endothelium, stroma, epithelium, or a combination can be affected. Little is known about the long-term outcomes of different types of IR. Methods We reviewed the medical records of all keratoplasties that had been performed at our eye centre between 2003 and 2016 (n = 3934) for any kind of IR that occurred between the surgery and 2019. All patients with a definite diagnosis of IR and sufficient clinical data were included in the analysis. IRs were grouped according to the affected part of the graft (endothelial, stromal, epithelial, and mixed). We analysed the dynamics of recovery and the clinical outcomes. Results We identified a total of 319 patients with IR. Twenty-seven of those were lost to follow-up and were excluded from further analysis. Of the IRs, 89% affected the endothelium. Endothelial IR resulted more frequently in a considerable loss of endothelial cell density than other forms of IR. Stromal IR showed a lower relapse rate and a better visual recovery than other types of IR and resulted less often in a failure of the graft. Conclusions We herein report comprehensive data about the prognosis regarding functional recovery after different types of IR following keratoplasty. Our data underline that timely recognition and correct classification of IR are important because they determine the clinical course and prognosis.

Scleroderma and Related Disorders

2017 ◽  
Author(s):  
Kristine Phillips
Keyword(s):  
Differential Diagnosis ◽  
Antinuclear Antibodies ◽  
Clinical Course ◽  
Clinical Manifestations ◽  
Diagnosis And Treatment ◽  
Localized Scleroderma ◽  
Eosinophilic Fasciitis ◽  
Tomographic Images ◽  
Computed Tomographic

Scleroderma spectrum diseases are a heterogeneous group of disorders that are distinguished by abnormalities of the connective tissue in the skin and, in some cases, other organs. Each disorder may be characterized by the extent of cutaneous and internal involvement, as well as histopathologic features of skin biopsy. Scleroderma spectrum diseases include systemic scleroderma, localized scleroderma, and eosinophilic fasciitis. This chapter reviews the classification, epidemiology, etiology, pathophysiology and pathogenesis, diagnosis, differential diagnosis, treatment, outcome measures, management, and clinical course of scleroderma as well as the definition and classification, etiology/genetics, differential diagnosis, and treatment of localized scleroderma. Also discussed are the definition and classification, epidemiology, etiology/genetics/pathogenesis, diagnosis, differential diagnosis, and treatment of eosinophilic fasciitis. Tables review the classification of—and antinuclear antibodies in—scleroderma as well as the key assessments and interventions in scleroderma management. Figures illustrate the disease's presentation and clinical manifestations, including several images of scleroderma of the hands; face, palmar, and buccal telangiectasias in a patient with scleroderma; a radiograph demonstrating calcinosis of the elbow; Raynaud’s phenomenon; high-resolution computed tomographic images of diffuse cutaneous scleroderma, scleroderma and severe pulmonary hypertension, and limited cutaneous scleroderma; plus an esophagram demonstrating hypomotility. This review contains 11 highly rendered figures, 3 tables, and 72 references.

Treatment of psychoses in the elderly

1996 ◽  
Vol 2 (3) ◽  
pp. 133-139
Author(s):  
A. Phanjoo
Keyword(s):  
Old Age ◽  
Psychotic Disorders ◽  
De Novo ◽  
Late Onset ◽  
Late Life ◽  
The Elderly ◽  
Functional Psychoses ◽  
First Time ◽  
Paranoid Psychosis

Psychotic disorders in the elderly can be divided into three types: disorders that have started in earlier life and persist into old age; disorders that start de novo after the age of 60, and psychoses associated with brain disease, including the dementias. The classification of psychoses in late life has provoked controversy for nearly a century. The debate concerns whether schizophrenia can present at any stage of life or whether functional psychoses, arising for the first time in late life, represent different illnesses. The nomenclature of such disorders consists of numerous terms including late onset schizophrenia, late paraphrenia, paranoid psychosis of late life and schizophreniform psychosis. This plethora of terms has made research difficult to interpret.

The Clinical Course of Primary Recurrent Depression in Pharmacologically Treated Female Patients

1975 ◽  
Vol 126 (4) ◽  
pp. 336-345 ◽  
Author(s):  
Tamara Kolakowska
Keyword(s):  
Clinical Studies ◽  
Clinical Course ◽  
Depressive Illness ◽  
Recurrent Depression ◽  
Female Patients ◽  
Affective Illness ◽  
Diagnosis And Classification ◽  
The Many

The main questions of diagnosis and classification of depressive illness put forward by Sir Aubrey Lewis in the 30's are still under discussion. Despite the many published clinical studies of affective illness, there remain—as recently stressed by Klerman (1971)—problems requiring further description and investigation.

scholarly journals The Clinical Impact of the Classification of Carcinoma In Situ on Tumor Recurrence and their Clinical Course in Patients with Bladder Tumor

2010 ◽  
Vol 41 (3) ◽  
pp. 424-429 ◽  
Author(s):  
N. Hayakawa ◽  
E. Kikuchi ◽  
S. Mikami ◽  
K. Matsumoto ◽  
A. Miyajima ◽  
...  
Keyword(s):  
Carcinoma In Situ ◽  
Tumor Recurrence ◽  
Bladder Tumor ◽  
Clinical Course ◽  
Clinical Impact

The pharmacologic stability of 35-year old theophylline

2002 ◽  
Vol 21 (6) ◽  
pp. 343-346 ◽  
Author(s):  
R Regenthal ◽  
D Stefanovic ◽  
T Albert ◽  
H Trauer ◽  
T Wolf
Keyword(s):  
Old Age ◽  
Clinical Picture ◽  
Drug Toxicity ◽  
Clinical Course ◽  
Beta Blockers ◽  
Expiration Date ◽  
Shelf Stability ◽  
Theophylline Poisoning ◽  
Accidental Drug Poisoning

The propensity to preserve and to hoard drugs over the years at home is a well-known phenomenon and offers the possibility for intentional and accidental drug poisoning in man. We report a case of acute theophylline poisoning in an 80-year old women after ingestion of ‘Asthmo-Kranit1 ’, a 35-year old combined preparation containing theophylline and aminopyrine as the main ingredients. The patient developed the typical clinical picture of a symptomatic theophylline poisoning with flush, tremor, tachycardia, hyperventilation, hypotonia, and hyperglycaemia. The clinical course after treatment with beta-blockers was without complications. The determination of theophylline in tablets showed stability of 90% of the labelled amount of the drug 30 years beyond the expiration date. The case illustrates the prolonged shelf stability and pharmacological potency of some pharmaceuticals and points to the risk of longoutdated prescriptions. Physicians should primarily not underestimate drug toxicity in consequence of old-age pharmaceuticals.

Sign in / Sign up

Export Citation Format

Share Document