Time-dependent expression of ryanodine receptors in sea urchin eggs, zygotes and early embryos
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Summary In this work, the presence of calcium-dependent calcium channels and their receptors (RyR) has been investigated in Paracentrotus lividus eggs and early embryos, from unfertilized egg to four-blastomere stages. Electrophysiological recordings of RyR single-channel current fluctuations showed that RyRs are functional during the first developmental events with a maximum at zygote stage, c. 40 min after fertilization, corresponding to the first cleavage. The nature of vertebrate-like RyRs active at this stage was established by specific activation/blockade experiments.
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1986 ◽
Vol 93
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pp. 195-204
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1995 ◽
Vol 269
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pp. C250-C256
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1990 ◽
Vol 64
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pp. 91-104
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1995 ◽
Vol 269
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pp. H443-H452
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1994 ◽
Vol 91
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pp. 4859-4863
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1997 ◽
Vol 110
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pp. 485-502
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2005 ◽
Vol 126
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pp. 339-352
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2000 ◽
Vol 174
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pp. 105-120
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