scholarly journals Validation of maternal recall on exclusive breastfeeding 12 months after childbirth

2020 ◽  
Vol 23 (14) ◽  
pp. 2494-2500
Author(s):  
BC Schneider ◽  
BO Cata-Preta ◽  
DD Gräf ◽  
DLR Silva ◽  
FS Santos ◽  
...  
Keyword(s):  
Birth Cohort ◽  
Exclusive Breastfeeding ◽  
Gold Standard ◽  
Population Based ◽  
Birth Cohort Study ◽  
Predictive Values ◽  
Maternal Report ◽  
Maternal Recall ◽  
Semi Solid ◽  
Sensitivity Specificity

AbstractObjective:We aimed to assess the validity of maternal recall of exclusive breastfeeding (EBF) at 3 months obtained 12 months after childbirth.Design:A population-based birth cohort study. The gold standard is maternal report of EBF at the age of 3 months (yes or no) and age of introduction of other foods in the infant’s diet. EBF was considered when the mother reported that no liquid, semi-solid or solid food was introduced up to that moment. The variable to be validated was obtained at 12 months after childbirth when the mother was asked about the age of food introduction. The prevalence of EBF at 3 months, and sensitivity, specificity, positive (PPV) and negative predictive values (NPV), and accuracy of 12-month recall with 95 % CI were calculated.Setting:Pelotas, Brazil.Participants:3700 mothers of participants of the Pelotas 2004 Birth Cohort.Results:The prevalence of EBF at 3 months was 27·8 % (95 % CI 26·4, 29·3) and 49·0 % (95 % CI 47·4, 50·6) according to gold standard and maternal recall, respectively. The sensitivity of maternal recall at 12 months was 98·3 % (95 % CI 97·4, 99·0), specificity 70·0 % (95 % CI 68·2, 71·7), PPV 55·8 % (95 % CI 53·4, 58·1), NPV 99·1 % (95 % CI 98·6, 99·5) and accuracy 77·9 % (95 % CI 76·6, 79·2). When the analyses were stratified by maternal and infant characteristics, the sensitivity remained around 98 %, and the specificity ranged from 64·4 to 81·8 %.Conclusions:EBF recalled at the end of the first year of infant’s life is a valid measure to be used in epidemiological investigations.

scholarly journals Investigation of the rapid immunochromatographic test performance in the diagnosis of syphilis; comparison of four serological methods

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Huseyin Agah Terzi ◽  
Ozlem Aydemir ◽  
Engin Karakece ◽  
Huseyin Hatipoglu ◽  
Mehmet Olmez ◽  
...  
Keyword(s):  
Test Performance ◽  
Gold Standard ◽  
Treponema Pallidum ◽  
Rapid Test ◽  
Immunochromatographic Test ◽  
Rapid Plasma Reagin ◽  
Serum Samples ◽  
Hemagglutination Assay ◽  
Predictive Values ◽  
Sensitivity Specificity

AbstractObjectivesTo test the performance of the newly available rapid test for syphilis, we compared it with Treponema pallidum hemagglutination assay (TPHA). Additionally, we investigated the performance of rapid plasma reagin (RPR) and chemiluminescence microparticle immunoassays (CMIA) at our laboratory using TPHA as a gold standard.MethodsThe serum samples of 595 patients with the pre-diagnosis of syphilis were studied by four serological methods. The sensitivity, specificity, and predictive values of RPR, CMIA, and syphilis rapid test were assessed by utilizing TPHA as a gold standard for the diagnosis of syphilis.ResultsOf the patients, 6.2% (37/595) had positive RPR, 5.5% (33/595) had positive CMIA, 5.5% (33/595) had a positive rapid immunochromatographic method and 5% (30/595) had positive TPHA. When TPHA results were taken as the reference, the sensitivity of the rapid test for syphilis was 100%, the specificity was 99.5%, PPV was 90.9%, and NPV was 100.0%.ConclusionsIt was observed that the rapid test for syphilis used in the study was quite successful, its cost was appropriate, and the test was very fast and easy to apply. At the same time, the agreement between syphilis rapid test and TPHA was found to be excellent.

Staphylococcus aureus sensitization and allergic disease in early childhood: Population-based birth cohort study

2007 ◽  
Vol 119 (4) ◽  
pp. 930-936 ◽  
Author(s):  
Aida Semic-Jusufagic ◽  
Claus Bachert ◽  
Philippe Gevaert ◽  
Gabriele Holtappels ◽  
Lesley Lowe ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Early Childhood ◽  
Cohort Study ◽  
Birth Cohort ◽  
Allergic Disease ◽  
Population Based ◽  
Birth Cohort Study ◽  
Childhood Population

scholarly journals The Protective Effect of Adenoidectomy on Pediatric Tympanostomy Tube Re-Insertions: A Population-Based Birth Cohort Study

PLoS ONE ◽  
2014 ◽  
Vol 9 (7) ◽  
pp. e101175 ◽  
Author(s):  
Mao-Che Wang ◽  
Ying-Piao Wang ◽  
Chia-Huei Chu ◽  
Tzong-Yang Tu ◽  
An-Suey Shiao ◽  
...  
Keyword(s):  
Cohort Study ◽  
Protective Effect ◽  
Birth Cohort ◽  
Population Based ◽  
Birth Cohort Study ◽  
Tympanostomy Tube

scholarly journals The discrepancy between manual and computerized leukocyte and thrombocyte counts

2016 ◽  
Vol 43 (3) ◽  
pp. 95
Author(s):  
Bambang Permono ◽  
Retno Asih ◽  
I Dewa Gede Ugrasena
Keyword(s):  
Gold Standard ◽  
Leukocyte Count ◽  
Predictive Values ◽  
Thrombocyte Count ◽  
Randomized Sampling ◽  
Manual Group ◽  
Manual Examination ◽  
Blood Specimens ◽  
Sensitivity Specificity ◽  
Normal Leukocyte

Background Discrepancy between results of leukocyte and throm-bocyte count by computerized and manual examination may existObjective To determine the discrepancy between computerizedand manual leukocyte and thrombocyte count.Methods The design was a randomized sampling cross sectionalstudy. The blood sample was examined with computerized CellDyn 1400 instrument for the leukocyte and thrombocyte count. Formanual examination, blood smear was performed to measurethrombocyte while leukocyte was measured in Improved Neubauerhemocytometer. The results of computerized examination wereused as gold standard. Sensitivity, specificity, predictive values ofmanual count were calculated. The agreement of Kappa and McNemar test were determinedResults Blood specimens drawn from 100 patients with differentkinds of diagnoses were examined using computerized and manualmethods. In computerized group, 66% had normal leukocyte and55% had normal thrombocyte count. In the manual group, 78% ofsubjects had normal leukocyte and 82% had normal thrombocytecount. From leukocyte examination, the sensitivity of manual countwas 87.9%, specificity was 41.2%, and positive predictive valuewas 74.36 with the agreement of Kappa of 0.32 and Mc Nemarvalue of 0.036. From thrombocyte examination, the sensitivity was96.4%, specificity was 35.6%, and positive predictive value was64.6 with the agreement of Kappa of 0.41 and Mc Nemar value of0.41.Conclusion The result of manual thrombocyte count was in ac-cordance with computerized with the agreement of Kappa of 0.41.On the other hand, there was a discrepancy between manual infavor of computerized leukocyte count with the agreement of Kappaof 0.32

scholarly journals The Role of MIR9-2 in Shared Susceptibility of Psychiatric Disorders during Childhood: A Population-Based Birth Cohort Study

Genes ◽  
2019 ◽  
Vol 10 (8) ◽  
pp. 626
Author(s):  
Luciana Tovo-Rodrigues ◽  
Gabriela Quinte ◽  
Clarice Brum ◽  
Gabriele Ghisleni ◽  
Clarissa Bastos ◽  
...  
Keyword(s):  
Psychiatric Disorders ◽  
Birth Cohort ◽  
Well Being ◽  
Externalizing Disorders ◽  
Population Based ◽  
Current Data ◽  
Birth Cohort Study ◽  
Structured Interviews ◽  
Protein Coding

Background: It has been suggested that microRNAs (miRNAs; short non-protein-coding RNA molecules that mediate post-transcriptional regulation), including mir-9 and mir-34 families, are important for brain development. Current data suggest that mir-9 and mir-34 may have shared effects across psychiatric disorders. This study aims to explore the role of genetic polymorphisms in the MIR9-2 (rs4916723) and MIR34B/C (rs4938723) genes on the susceptibility of psychiatric disorders in children from the 2004 Pelotas Birth Cohort. Methods: Psychiatric disorders were assessed in 3585 individuals using Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV), criteria through the application of standard semi-structured interviews (using the Development and Well-Being Assessment, DAWBA) at the six-years-of-age follow-up. The outcome was defined as the presence of any mental disorder. We also considered two broad groups of internalizing and externalizing disorders to further investigate the role of these variants in mental health. Results: We observed an association between rs4916723 (MIR9-2) and the presence of any psychiatric disorder (odds ratios (OR) = 0.820; 95% CI = 0.7130–0.944; p = 0.006) and a suggestive effect on internalizing disorders (OR = 0.830; 95% CI = 0.698–0.987; p = 0.035). rs4938723 (MIR34B/C) was not associated with any evaluated outcome. Conclusion: The study suggests that MIR9-2 may have an important role on a broad susceptibility for psychiatric disorders and may be important mainly for internalization problems.

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