scholarly journals Ferritin Mineral Core Composition in Health and Disease

2016 ◽  
Vol 22 (S3) ◽  
pp. 1156-1157
Author(s):  
Angela Blissett ◽  
Brooke Ollander ◽  
Binbin Deng ◽  
Tanya Nocera ◽  
Edward Calomeni ◽  
...  
1988 ◽  
Vol 25 (9) ◽  
pp. 1464-1471 ◽  
Author(s):  
J. V. Owen ◽  
J. D. Greenough ◽  
Charlotte Hy ◽  
Alan Ruffman

A recently recognized series of northwest-trending mafic dykes cuts the Cambro-Ordovician Meguma Group along the eastern shore of Nova Scotia. Some of the dykes contain gneissic and (meta)plutonic xenoliths interpreted here as including fragments of the basement to the Meguma Group.Most of the gneissic xenoliths in the dyke exposed at Popes Harbour are sillimanite- and (or) kyanite-bearing quartz-poor metapelites and garnet + orthopyroxene-bearing tonalitic rock. Other enclaves include amphibolite, quartzite, gabbro, granite–granodiorite, and granitic pegmatite. Textural features suggest that the earliest paragneissic assemblage included poikiloblastic garnet (XFe = 0.55–0.65, XMg = 0.05–0.30, XCa = 0.02–0.16, XMn = 0.02–0.16), biotite, kyanite and (or) sillimanite, oligoclase, and quartz. Subsequent recrystallization at higher temperature and (or) lower pressure conditions is suggested by the replacement of kyanite by sillimanite. Mineral core composition data indicate early metamorphic conditions of ~450–600 MPa (gt–Al2SiO5–pl–qz and gt–opx–pi–qz barometers) and at least 600 °C (gt–bi and opx–gt thermometers), which lie close to the kyanite–sillimanite boundary and do not clearly distinguish the kyanite- and sillimanite-forming events. Other relatively high temperature and (or) lower pressure texturally overprinting assemblages include, in the pelites, (i) sapphirine (XMg = 0.75), spinel (XMg = 0.45–0.65), corundum, and rutile (all with anatectic(?) calcic plagioclase or ternary feldspar rims); and (ii) calcic rims on plagioclase and pyrope-rich overgrowths on garnet in both pelitic and tonalitic gneiss.The polymict assemblage of xenoliths in the Popes Harbour dyke testifies to the heterogeneity of the basement to the Meguma Group.


Author(s):  
Sarah A. Luse

In the mid-nineteenth century Virchow revolutionized pathology by introduction of the concept of “cellular pathology”. Today, a century later, this term has increasing significance in health and disease. We now are in the beginning of a new era in pathology, one which might well be termed “organelle pathology” or “subcellular pathology”. The impact of lysosomal diseases on clinical medicine exemplifies this role of pathology of organelles in elucidation of disease today.Another aspect of cell organelles of prime importance is their pathologic alteration by drugs, toxins, hormones and malnutrition. The sensitivity of cell organelles to minute alterations in their environment offers an accurate evaluation of the site of action of drugs in the study of both function and toxicity. Examples of mitochondrial lesions include the effect of DDD on the adrenal cortex, riboflavin deficiency on liver cells, elevated blood ammonia on the neuron and some 8-aminoquinolines on myocardium.


2011 ◽  
Vol 21 (3) ◽  
pp. 112-117 ◽  
Author(s):  
Elizabeth Erickson-Levendoski ◽  
Mahalakshmi Sivasankar

The epithelium plays a critical role in the maintenance of laryngeal health. This is evident in that laryngeal disease may result when the integrity of the epithelium is compromised by insults such as laryngopharyngeal reflux. In this article, we will review the structure and function of the laryngeal epithelium and summarize the impact of laryngopharyngeal reflux on the epithelium. Research investigating the ramifications of reflux on the epithelium has improved our understanding of laryngeal disease associated with laryngopharyngeal reflux. It further highlights the need for continued research on the laryngeal epithelium in health and disease.


1965 ◽  
Vol 48 (6) ◽  
pp. 758-767 ◽  
Author(s):  
Lansing C. Hoskins ◽  
Norman Zamcheck

1959 ◽  
Vol 36 (2) ◽  
pp. 193-201 ◽  
Author(s):  
Julius A. Goldbarg ◽  
Esteban P. Pineda ◽  
Benjamin M. Banks ◽  
Alexander M. Rutenburg

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