Paper-Based Microfluidic Surface Acoustic Wave Sample Delivery and Ionization Source for Rapid and Sensitive Ambient Mass Spectrometry

2011 ◽  
Vol 83 (9) ◽  
pp. 3260-3266 ◽  
Author(s):  
Jenny Ho ◽  
Ming K. Tan ◽  
David B. Go ◽  
Leslie Y. Yeo ◽  
James R. Friend ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Ambient Mass Spectrometry ◽  
Ionization Source

Thermal bursting ionization for ambient mass spectrometry

RSC Advances ◽  
2016 ◽  
Vol 6 (3) ◽  
pp. 2496-2499 ◽  
Author(s):  
Jiying Pei ◽  
Kefu Yu ◽  
Yinghui Wang
Keyword(s):  
Mass Spectrometry ◽  
Ambient Ionization ◽  
Ambient Mass Spectrometry ◽  
Sample Analysis ◽  
Liquid Sample ◽  
Ionization Source ◽  
Complex Liquid

Ambient ionization source, thermal bursting ionization (TBI), was characterized for complex liquid sample analysis with mass spectrometry.

scholarly journals Surface acoustic wave nebulization improves compound selectivity of low-temperature plasma ionization for mass spectrometry

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Andreas Kiontke ◽  
Mehrzad Roudini ◽  
Susan Billig ◽  
Amarghan Fakhfouri ◽  
Andreas Winkler ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Low Temperature ◽  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Ionization Mechanism ◽  
Low Temperature Plasma ◽  
Ambient Conditions ◽  
Temperature Plasma ◽  
Plasma Ionization ◽  
Surface Acoustic Wave Nebulization

AbstractMass spectrometry coupled to low-temperature plasma ionization (LTPI) allows for immediate and easy analysis of compounds from the surface of a sample at ambient conditions. The efficiency of this process, however, strongly depends on the successful desorption of the analyte from the surface to the gas phase. Whilst conventional sample heating can improve analyte desorption, heating is not desirable with respect to the stability of thermally labile analytes. In this study using aromatic amines as model compounds, we demonstrate that (1) surface acoustic wave nebulization (SAWN) can significantly improve compound desorption for LTPI without heating the sample. Furthermore, (2) SAWN-assisted LTPI shows a response enhancement up to a factor of 8 for polar compounds such as aminophenols and phenylenediamines suggesting a paradigm shift in the ionization mechanism. Additional assets of the new technique demonstrated here are (3) a reduced analyte selectivity (the interquartile range of the response decreased by a factor of 7)—a significant benefit in non-targeted analysis of complex samples—and (4) the possibility for automated online monitoring using an autosampler. Finally, (5) the small size of the microfluidic SAWN-chip enables the implementation of the method into miniaturized, mobile LTPI probes.

scholarly journals Author Correction: Surface acoustic wave nebulization improves compound selectivity of low-temperature plasma ionization for mass spectrometry

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Andreas Kiontke ◽  
Mehrzad Roudini ◽  
Susan Billig ◽  
Armaghan Fakhfouri ◽  
Andreas Winkler ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Low Temperature ◽  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Low Temperature Plasma ◽  
Temperature Plasma ◽  
Plasma Ionization ◽  
Surface Acoustic Wave Nebulization

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

scholarly journals Rapid Food Product Analysis by Surface Acoustic Wave Nebulization Coupled Mass Spectrometry

2018 ◽  
Vol 11 (9) ◽  
pp. 2447-2454 ◽  
Author(s):  
Thomas Schneider ◽  
Benjamin L. Oyler ◽  
Sung Hwan Yoon ◽  
Tao Liang ◽  
Gloria S. Yen ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Food Product ◽  
Product Analysis ◽  
Surface Acoustic Wave Nebulization

Droplet delivery and nebulization system using surface acoustic wave for mass spectrometry

Lab on a Chip ◽  
2020 ◽  
Vol 20 (17) ◽  
pp. 3269-3277
Author(s):  
Di Sun ◽  
Karl F. Böhringer ◽  
Matthew Sorensen ◽  
Erik Nilsson ◽  
J. Scott Edgar ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Sample Preparation ◽  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Standing Wave ◽  
Piezoelectric Transducer ◽  
Wave Surface ◽  
Surface Acoustic Wave Nebulization

We present a piezoelectric transducer for standing wave surface acoustic wave nebulization (SW-SAWN) patterned with anisotropic ratchet conveyors (ARCs) to automate the sample preparation and droplet delivery.

Microwave-Induced Plasma Desorption/Ionization Source for Ambient Mass Spectrometry

2013 ◽  
Vol 85 (9) ◽  
pp. 4512-4519 ◽  
Author(s):  
Xuefang Zhan ◽  
Zhongjun Zhao ◽  
Xin Yuan ◽  
Qihui Wang ◽  
Dandan Li ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Ambient Mass Spectrometry ◽  
Ionization Source ◽  
Microwave Induced Plasma ◽  
Desorption Ionization ◽  
Plasma Desorption

Rapid lipid a structure determination via surface acoustic wave nebulization and hierarchical tandem mass spectrometry algorithm

2016 ◽  
Vol 30 (23) ◽  
pp. 2555-2560 ◽  
Author(s):  
Sung Hwan Yoon ◽  
Tao Liang ◽  
Thomas Schneider ◽  
Benjamin L. Oyler ◽  
Courtney E. Chandler ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Acoustic Wave ◽  
Tandem Mass Spectrometry ◽  
Surface Acoustic Wave ◽  
Structure Determination ◽  
Lipid A ◽  
Tandem Mass ◽  
Lipid A Structure ◽  
Surface Acoustic Wave Nebulization

Combining Mass Spectrometry, Surface Acoustic Wave Interaction Analysis, and Cell Viability Assays for Characterization of Shiga Toxin Subtypes of PathogenicEscherichia coliBacteria

2018 ◽  
Vol 90 (15) ◽  
pp. 8989-8997 ◽  
Author(s):  
Daniel Steil ◽  
Gottfried Pohlentz ◽  
Nadine Legros ◽  
Michael Mormann ◽  
Alexander Mellmann ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Acoustic Wave ◽  
Cell Viability ◽  
Surface Acoustic Wave ◽  
Shiga Toxin ◽  
Interaction Analysis ◽  
Wave Interaction
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