Conformer-Specific Hydrogen Exchange Analysis of Aβ(1–42) Oligomers by Top-Down Electron Capture Dissociation Mass Spectrometry

2011 ◽  
Vol 83 (13) ◽  
pp. 5386-5393 ◽  
Author(s):  
Jingxi Pan ◽  
Jun Han ◽  
Christoph H. Borchers ◽  
Lars Konermann
Keyword(s):  
Mass Spectrometry ◽  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Hydrogen Exchange ◽  
Top Down

scholarly journals Electron capture dissociation and drift tube ion mobility-mass spectrometry coupled with site directed mutations provide insights into the conformational diversity of a metamorphic protein

2015 ◽  
Vol 17 (16) ◽  
pp. 10538-10550 ◽  
Author(s):  
Sophie R. Harvey ◽  
Massimiliano Porrini ◽  
Robert C. Tyler ◽  
Cait E. MacPhee ◽  
Brian F. Volkman ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Ion Mobility ◽  
Drift Tube ◽  
Ion Mobility Mass Spectrometry ◽  
Top Down ◽  
Conformational Diversity ◽  
Metamorphic Protein

Ion mobility mass spectrometry can be combined with data from top-down sequencing to discern adopted conformations of proteins in the absence of solvent.

scholarly journals Top down characterization of secreted proteins from Mycobacterium tuberculosis by electron capture dissociation mass spectrometry

2003 ◽  
Vol 14 (3) ◽  
pp. 253-261 ◽  
Author(s):  
Ying Ge ◽  
Mariam ElNaggar ◽  
Siu Kwan Sze ◽  
Han Bin Oh ◽  
Tadhg P. Begley ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Mycobacterium Tuberculosis ◽  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Secreted Proteins ◽  
Top Down

Top-Down Structural Analysis of an Intact Monoclonal Antibody by Electron Capture Dissociation-Fourier Transform Ion Cyclotron Resonance-Mass Spectrometry

2013 ◽  
Vol 85 (9) ◽  
pp. 4239-4246 ◽  
Author(s):  
Yuan Mao ◽  
Santosh G. Valeja ◽  
Jason C. Rouse ◽  
Christopher L. Hendrickson ◽  
Alan G. Marshall
Keyword(s):  
Mass Spectrometry ◽  
Monoclonal Antibody ◽  
Fourier Transform ◽  
Structural Analysis ◽  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Cyclotron Resonance ◽  
Ion Cyclotron Resonance ◽  
Top Down ◽  
Ion Cyclotron

scholarly journals Mapping a Noncovalent Protein–Peptide Interface by Top-Down FTICR Mass Spectrometry Using Electron Capture Dissociation

2011 ◽  
Vol 22 (8) ◽  
pp. 1432-1440 ◽  
Author(s):  
David J. Clarke ◽  
Euan Murray ◽  
Ted Hupp ◽  
C. Logan Mackay ◽  
Pat R. R. Langridge-Smith
Keyword(s):  
Mass Spectrometry ◽  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Top Down ◽  
Fticr Mass Spectrometry ◽  
Noncovalent Protein

scholarly journals Sequencing Grade Tandem Mass Spectrometry for Top–Down Proteomics Using Hybrid Electron Capture Dissociation Methods in a Benchtop Orbitrap Mass Spectrometer

2018 ◽  
Vol 90 (18) ◽  
pp. 10819-10827 ◽  
Author(s):  
Jared B. Shaw ◽  
Neha Malhan ◽  
Yury V. Vasil’ev ◽  
Nathan I. Lopez ◽  
Alexander Makarov ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Electron Capture ◽  
Mass Spectrometer ◽  
Electron Capture Dissociation ◽  
Tandem Mass ◽  
Top Down ◽  
Orbitrap Mass Spectrometer

scholarly journals Native Electrospray and Electron-Capture Dissociation FTICR Mass Spectrometry for Top-Down Studies of Protein Assemblies

2011 ◽  
Vol 83 (14) ◽  
pp. 5598-5606 ◽  
Author(s):  
Hao Zhang ◽  
Weidong Cui ◽  
Jianzhong Wen ◽  
Robert E. Blankenship ◽  
Michael L. Gross
Keyword(s):  
Mass Spectrometry ◽  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Protein Assemblies ◽  
Top Down ◽  
Fticr Mass Spectrometry
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