Pressure-Sensitive Adhesive Combined with Paper Spray Mass Spectrometry for Low-Cost Collection and Analysis of Drug Residues

This study investigated the addition of acrylic fiber to old corrugated container (OCC) pulp as a possible means of overcoming adverse effects of water-based pressure sensitive adhesives during manufacture of paper or paperboard. Such adhesives can constitute a main source of stickies, which hurt the efficiency of the papermaking process and make tacky spots in the product. The highest amount of acrylic fiber added to recycled pulps generally resulted in a 77% reduction in accepted pulp microstickies. The addition of acrylic fibers also increased pulp freeness, tear index, burst strength, and breaking length, though there was a reduction in screen yield. Hence, in addition to controlling the adverse effects of stickies, the addition of acrylic fibers resulted in the improvement of the mechanical properties of paper compared with a control sample.

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Application of pressure-sensitive adhesive systems in laser-beam welding of lap joints

International Congress on Applications of Lasers & Electro-Optics ◽

10.2351/1.5061555 ◽

2009 ◽

Author(s):

Uwe Reisgen ◽

Klaus Dilger ◽

Simon Olschok ◽

Nikolaus Wagner

Keyword(s):

Laser Beam ◽

Laser Beam Welding ◽

Lap Joints ◽

Adhesive Systems ◽

Pressure Sensitive Adhesive ◽

Pressure Sensitive

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Rapid Diagnosis of Parkinson’s Disease from Sebum using Paper Spray Ionisation Ion Mobility Mass Spectrometry

10.26434/chemrxiv.12517385.v1 ◽

2020 ◽

Author(s):

Depanjan Sarkar ◽

Drupad Trivedi ◽

Eleanor Sinclair ◽

Sze Hway Lim ◽

Caitlin Walton-Doyle ◽

...

Keyword(s):

Mass Spectrometry ◽

Parkinson’S Disease ◽

Parkinson's Disease ◽

Ion Mobility ◽

Neurodegenerative Disorder ◽

Treatment Options ◽

Ion Mobility Mass Spectrometry ◽

Paper Spray ◽

Molecular Features ◽

Validation Set

Parkinson’s disease (PD) is the second most common neurodegenerative disorder for which identification of robust biomarkers to complement clinical PD diagnosis would accelerate treatment options and help to stratify disease progression. Here we demonstrate the use of paper spray ionisation coupled with ion mobility mass spectrometry (PSI IM-MS) to determine diagnostic molecular features of PD in sebum. PSI IM-MS was performed directly from skin swabs, collected from 34 people with PD and 30 matched control subjects as a training set and a further 91 samples from 5 different collection sites as a validation set. PSI IM-MS elucidates ~ 4200 features from each individual and we report two classes of lipids (namely phosphatidylcholine and cardiolipin) that differ significantly in the sebum of people with PD. Putative metabolite annotations are obtained using tandem mass spectrometry experiments combined with accurate mass measurements. Sample preparation and PSI IM-MS analysis and diagnosis can be performed ~5 minutes per sample offering a new route to for rapid and inexpensive confirmatory diagnosis of this disease.

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