Identifying Protein–Drug Interactions in Cell Lysates Using Histidine Hydrogen Deuterium Exchange

Analytical Chemistry ◽

10.1021/acs.analchem.1c02283 ◽

2021 ◽

Author(s):

Masaru Miyagi ◽

Kohei Tanaka ◽

Shinko Watanabe ◽

Jun Kondo ◽

Taro Kishimoto

Keyword(s):

Drug Interactions ◽

Deuterium Exchange ◽

Protein Drug ◽

Hydrogen Deuterium Exchange ◽

Cell Lysates ◽

Hydrogen Deuterium

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Detection of structural and conformational changes in ALS-causing mutant profilin-1 with hydrogen/deuterium exchange mass spectrometry and bioinformatics techniques

Metabolic Brain Disease ◽

10.1007/s11011-021-00763-y ◽

2021 ◽

Author(s):

Ahmad Shahir Sadr ◽

Zahra Abdollahpour ◽

Atousa Aliahmadi ◽

Changiz Eslahchi ◽

Mina Nekouei ◽

...

Keyword(s):

Mass Spectrometry ◽

Conformational Changes ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry

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Alkali metal ion-induced conformation changes of methionine- and leucine enkephalin investigated by gas-phase hydrogen/deuterium exchange combined with theoretical calculations

Journal of Molecular Structure ◽

10.1016/j.molstruc.2021.130113 ◽

2021 ◽

Vol 1233 ◽

pp. 130113

Author(s):

Fangling Wu ◽

Yizhen Wang ◽

Yinjuan Chen ◽

Zhenhua Li ◽

Chuan-Fan Ding

Keyword(s):

Alkali Metal ◽

Gas Phase ◽

Metal Ion ◽

Theoretical Calculations ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Alkali Metal Ion ◽

Leucine Enkephalin ◽

Conformation Changes ◽

Hydrogen Deuterium

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Calculation of reaction rate constants for hydrogen–deuterium exchange reactions of methane catalysed by acid zeolites

Chemical Communications ◽

10.1039/b102249k ◽

2001 ◽

pp. 1108-1109 ◽

Author(s):

Ann M. Vos ◽

Robert A. Schoonheydt ◽

Frank De Proft ◽

Paul Geerlings

Keyword(s):

Rate Constants ◽

Reaction Rate ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Reactions ◽

Reaction Rate Constants ◽

Acid Zeolites ◽

Hydrogen Deuterium

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A simple method for differentiation of monoisotopic drug metabolites with hydrogen–deuterium exchange liquid chromatography/electrospray mass spectrometry

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2005.02.005 ◽

2005 ◽

Vol 25 (1) ◽

pp. 155-162 ◽

Author(s):

Ari Tolonen ◽

Miia Turpeinen ◽

Jouko Uusitalo ◽

Olavi Pelkonen

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Electrospray Mass Spectrometry ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Simple Method ◽

Drug Metabolites ◽

Hydrogen Deuterium

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Ab initio molecular dynamics study of the hydrogen-deuterium exchange in bulk lithiumborohydride (LiBH4)

Applied Physics Letters ◽

10.1063/1.3115032 ◽

2009 ◽

Vol 94 (14) ◽

pp. 141903 ◽

Author(s):

M. Ramzan ◽

R. Ahuja

Keyword(s):

Molecular Dynamics ◽

Ab Initio ◽

Deuterium Exchange ◽

Ab Initio Molecular Dynamics ◽

Hydrogen Deuterium Exchange ◽

Hydrogen Deuterium

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Use of 1,5-diaminonaphthalene to combine matrix-assisted laser desorption/ionization in-source decay fragmentation with hydrogen/deuterium exchange

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.6627 ◽

2013 ◽

Vol 27 (16) ◽

pp. 1837-1846 ◽

Author(s):

Pascale Lemaire ◽

Delphine Debois ◽

Nicolas Smargiasso ◽

Loïc Quinton ◽

Valérie Gabelica ◽

...

Keyword(s):

Laser Desorption ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Laser Desorption Ionization ◽

Desorption Ionization ◽

Hydrogen Deuterium ◽

Matrix Assisted Laser ◽

Matrix Assisted Laser Desorption

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Design and Validation of In-Source Atmospheric Pressure Photoionization Hydrogen/Deuterium Exchange Mass Spectrometry with Continuous Feeding of D2O

Journal of the American Society for Mass Spectrometry ◽

10.1007/s13361-017-1831-8 ◽

2017 ◽

Vol 29 (1) ◽

pp. 85-94 ◽

Author(s):

Thamina Acter ◽

Seulgidaun Lee ◽

Eunji Cho ◽

Maeng-Joon Jung ◽

Sunghwan Kim

Keyword(s):

Mass Spectrometry ◽

Atmospheric Pressure ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Atmospheric Pressure Photoionization ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry ◽

Continuous Feeding

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New developments in protein structure-function analysis by MS and use of hydrogen-deuterium exchange microfluidics

FEBS Journal ◽

10.1111/j.1742-4658.2011.08215.x ◽

2011 ◽

Vol 278 (20) ◽

pp. 3815-3821 ◽

Author(s):

Michael Landreh ◽

Juan Astorga-Wells ◽

Jan Johansson ◽

Tomas Bergman ◽

Hans Jörnvall

Keyword(s):

Protein Structure ◽

Structure Function ◽

Function Analysis ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

New Developments ◽

Hydrogen Deuterium

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Intramolecular hydrogen—deuterium exchange in isomeric methyl ethyl esters of phenylmaleic, -fumaric, and -succinic acids under chemical ionization: low energy CID study and geometrical requirements of the exchange

International Journal of Mass Spectrometry and Ion Processes ◽

10.1016/0168-1176(90)85095-j ◽

1990 ◽

Vol 100 ◽

pp. 565-577 ◽

Author(s):

A. Mandelbaum ◽

D.R. Müller ◽

W.J. Richter ◽

I. Vidavsky

Keyword(s):

Chemical Ionization ◽

Deuterium Exchange ◽

Ethyl Esters ◽

Hydrogen Deuterium Exchange ◽

Methyl Ethyl ◽

Hydrogen Deuterium ◽

Intramolecular Hydrogen ◽

Isomeric Methyl

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Different conformational dynamics of various active states of β-arrestin1 analyzed by hydrogen/deuterium exchange mass spectrometry

Journal of Structural Biology ◽

10.1016/j.jsb.2015.04.006 ◽

2015 ◽

Vol 190 (2) ◽

pp. 250-259 ◽

Author(s):

Dong Kyun Kim ◽

Youngjoo Yun ◽

Hee Ryung Kim ◽

Min-Duk Seo ◽

Ka Young Chung

Keyword(s):

Mass Spectrometry ◽

Conformational Dynamics ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry

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