Use of Multiple Peptide-Based SERS Probes Binding to Different Epitopes on a Protein Biomarker To Improve Detection Sensitivity

2016 ◽  
Vol 88 (7) ◽  
pp. 3465-3470 ◽  
Author(s):  
Kayeong Shin ◽  
Jun-Haeng Cho ◽  
Moon-Young Yoon ◽  
Hoeil Chung
Keyword(s):  
Detection Sensitivity ◽  
Protein Biomarker ◽  
Improve Detection Sensitivity

Quantitative analysis with a two-detector measuring system in in-air PIXE-design to improve detection sensitivity at low energies

2013 ◽  
Vol 23 (01n02) ◽  
pp. 55-67 ◽  
Author(s):  
K. Sera ◽  
S. Goto ◽  
C. Takahashi ◽  
Y. Saitoh
Keyword(s):  
Quantitative Analysis ◽  
Production Cross ◽  
Detection Sensitivity ◽  
Measuring System ◽  
X Rays ◽  
Standard Material ◽  
X Ray ◽  
New Device ◽  
Low Energies ◽  
Improve Detection Sensitivity

In this paper, a two-detector measuring system in in-air PIXE system composed of two Si(Li) detectors has been developed for simultaneous measurement of low- and high-Z elements. In order to improve detection sensitivity of the detector for low energy region, a new device which is attached at the tip of the detector has been designed. It is made of acryl and has a thin end on which a 1.5 μm-thick Mylar film is stuck. As a result, it exhibited a miraculous effect in improving detection sensitivity at low energies and it became possible to detect K X-rays of aluminium. In order to perform quantitative analysis in in-air system, we have measured detection efficiencies for the two Si(Li) detectors including the effect of X-ray absorption in air on the basis of the method that we developed. Concerning the beam energy at the target and corresponding X-ray production cross-sections, the same values as were reported in the previous paper were applicable since conditions of irradiating system were unchanged. It was confirmed that the new method allows us to quantitatively analyze all the elements heavier than aluminum and to obtain mostly the same results as those by in-vacuum PIXE for various kinds of samples. Accuracy of analysis was also confirmed by using a standard material.

Quantitative and Systematical Designing Fluorophores Enables Ultrasensitive Distinguishing Carbonyls

2021 ◽  
Author(s):  
Lei Shi ◽  
Chenxu Yan ◽  
Yunyu Li ◽  
Lixiang Yang ◽  
Wenle Mao ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Detection Sensitivity ◽  
Individual Species ◽  
Quantitative Design ◽  
Improve Detection Sensitivity

Although the sophisticated fluorescent probes can improve detection sensitivity, either the lack of quantitative design for fluorophores or the deficiency of selectivity towards individual species makes it extremely difficult to...

scholarly journals Digital PCR methods improve detection sensitivity and measurement precision of low abundance mtDNA deletions

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Frances R. Belmonte ◽  
James L. Martin ◽  
Kristin Frescura ◽  
Joana Damas ◽  
Filipe Pereira ◽  
...  
Keyword(s):  
Digital Pcr ◽  
Measurement Precision ◽  
Detection Sensitivity ◽  
Mtdna Deletions ◽  
Improve Detection Sensitivity

scholarly journals Use of Rapid-Scan EPR to Improve Detection Sensitivity for Spin-Trapped Radicals

2013 ◽  
Vol 105 (2) ◽  
pp. 338-342 ◽  
Author(s):  
Deborah G. Mitchell ◽  
Gerald M. Rosen ◽  
Mark Tseitlin ◽  
Breanna Symmes ◽  
Sandra S. Eaton ◽  
...  
Keyword(s):  
Detection Sensitivity ◽  
Rapid Scan ◽  
Improve Detection Sensitivity

scholarly journals Trapping Brown Marmorated Stink Bugs: “The Nazgȗl” Lure and Kill Nets

Insects ◽  
2019 ◽  
Vol 10 (12) ◽  
pp. 433
Author(s):  
David Maxwell Suckling ◽  
Valerio Mazzoni ◽  
Gerardo Roselli ◽  
Mary Claire Levy ◽  
Claudio Ioriatti ◽  
...  
Keyword(s):  
Aggregation Pheromone ◽  
Low Cost ◽  
Detection Sensitivity ◽  
Halyomorpha Halys ◽  
Pesticide Use ◽  
Brown Marmorated Stink Bug ◽  
Stink Bug ◽  
Stink Bugs ◽  
Population Suppression ◽  
Improve Detection Sensitivity

Improvements to current brown marmorated stink bug (BMSB), Halyomorpha halys, surveillance and killing systems are needed to improve detection sensitivity and to reduce pesticide use. Detection of BMSB in New Zealand with traps is reliant on sticky panels with aggregation pheromone, which are low cost but inefficient compared with beating foliage. Trapping for BMSB adults and nymphs was conducted daily with lethal traps consisting of an aggregation pheromone-baited-coat hanger covered with dark-colored long-lasting insecticide-treated mesh, we termed “The Nazgȗl”, based on its sinister appearance. A deep tray lined with white plastic was attached centrally at the base for collecting the dead BMSB. The lethal traps killed and caught up to 3.5-fold more nymphs and adult BMSB than identically-baited sticky panels in the 3 weeks of deployment, and provided a snapshot of phenology by instar. We expect that lure-and-kill stations could contribute to the suppression of a delimited population and could be included as part of a semiochemical-based eradication program. Attracting and killing females and nymphs, thus removing future offspring, could contribute to population suppression during an eradication.

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