Factors Associated with Levels of Organophosphate Pesticides in Household Dust in Agricultural Communities

Organophosphate (OP) pesticides are associated with numerous adverse health outcomes. Pesticide use data are available for California from the Pesticide Use Report (PUR), but household- and individual-level exposure factors have not been fully characterized to support its refinement as an exposure assessment tool. Unique exposure pathways, such as proximity to agricultural operations and direct occupational contact, further complicate pesticide exposure assessment among agricultural communities. We sought to identify influencing factors of pesticide exposure to support future exposure assessment and epidemiological studies. Household dust samples were collected from 28 homes in four California agricultural communities during January and June 2019 and were analyzed for the presence of OPs. Factors influencing household OPs were identified by a data-driven model via best subsets regression. Key factors that impacted dust OP levels included household cooling strategies, secondary occupational exposure to pesticides, and geographic location by community. Although PUR data demonstrate seasonal trends in pesticide application, this study did not identify season as an important factor, suggesting OP persistence in the home. These results will help refine pesticide exposure assessment for future studies and highlight important gaps in the literature, such as our understanding of pesticide degradation in an indoor environment.

Chromatographic Techniques for the Analysis of Organophosphate Pesticides with their Extraction Approach: A Review (2015-2020)

In agriculture, a wide range of OPPs have been employed to boost crop yield, quality, and storage life. However, due to the ever-increasing population and rapid urbanization, pesticide use has...

Environmental exposures contribute to respiratory and allergic symptoms among women living in the banana growing regions of Costa Rica

ObjectivesThis research evaluates whether environmental exposures (pesticides and smoke) influence respiratory and allergic outcomes in women living in a tropical, agricultural environment.MethodsWe used data from 266 mothers from the Infants’ Environmental Health cohort study in Costa Rica. We evaluated environmental exposures in women by measuring seven pesticide and two polycyclic aromatic hydrocarbons metabolites in urine samples. We defined ‘high exposure’ as having a metabolite value in the top 75th percentile. We collected survey data on respiratory and allergic outcomes in mothers as well as on pesticides and other environmental exposures. Using logistic regression models adjusted for obesity, we assessed the associations of pesticide exposure with multiple outcomes (wheeze, doctor-diagnosed asthma, high (≥2) asthma score based on symptoms, rhinitis, eczema and itchy rash).ResultsCurrent pesticide use in the home was positively associated with diagnosed asthma (OR=1.99 (95% CI=1.05 to 3.87)). High urinary levels of 5-hydroxythiabendazole (thiabendazole metabolite) and living in a neighbourhood with frequent smoke from waste burning were associated with a high asthma score (OR=1.84 (95%CI=1.05 to 3.25) and OR=2.31 (95%CI=1.11 to 5.16), respectively). Women who worked in agriculture had a significantly lower prevalence of rhinitis (0.19 (0.01 to 0.93)), but were more likely to report eczema (OR=2.54 (95%CI=1.33 to 4.89)) and an itchy rash (OR=3.17 (95%CI=1.24 to 7.73)).ConclusionsWhile limited by sample size, these findings suggest that environmental exposure to both pesticides and smoke may impact respiratory and skin-related allergic outcomes in women.

Effect of Insecticides on Natural-Enemies

Pesticides management options for control of invertebrate pests in many parts of the world. Despite an increase in the use of pesticides, crop losses due to pests have remained largely unchanged for 30–40 years. Beyond the target pests, broad-spectrum pesticides may affect non-target invertebrate species, including causing reductions in natural enemy population abundance and activity, and competition between pest species. Assays of invertebrates against weathered residues have shown the persistence of pesticides might play an important part in their negative impacts on natural enemies in the field. A potential outcome of frequent broad-spectrum pesticide use is the emergence of pests not controlled by the pesticides but benefiting from reduced mortality from natural enemies and competitive release, commonly known as secondary pests.

Parkinson’s disease hospitalization rates and pesticide use in urban and non-urban regions of Brazil

Background Few studies have evaluated the role played by pesticide exposure in the development of Parkinson’s disease (PD) in Brazil. Objective This study aimed to investigate the association between pesticide use and PD hospitalization in Brazilian micro-regions. Method Pesticide expenditure per capita in 1985 and PD hospitalization rates (HR) from 1997 to 2007 were calculated for all 552 Brazilian micro-regions. The Spearman's correlation test was used to compare pesticide expenditure and PD HR by sex, age, and urban and non-urban micro-regions. Micro-regions were grouped according to the quintiles of pesticide expenditure. PD HR ratios (HRR) were calculated to compare PD HR across the quintiles of pesticide expenditure. Results Moderate correlation (r=0.518; p<0.001) between PD HR in non-urban micro-regions and pesticide expenditure was observed. In non-urban areas, compared with micro-regions of the first quintile of pesticide use, PD HRR ranged from 1.70 to 5.90 in micro-regions of higher pesticide use. In general, regardless of sex and age, the higher the use of pesticides, the greater the magnitude of PD HRR. Conclusion Our results suggest that pesticide use is associated with PD in Brazil, especially in non-urban areas where pesticides are used more intensively.

Copper use in organic agriculture in twelve European countries.

Reduction of copper-based fungicides with the final aim of phasing out has a high priority in European policy as well as in organic agriculture. Our survey aims at providing an overview of the current use of copper-based plant protection products in European organic agriculture and the need for alternatives to allow policy makers to develop strategies for a complete phasing out. Due to a lack of centralized databases on pesticide use, our survey combines expert knowledge on permitted and real copper use per crop and country with statistics on organic area. In the 12 surveyed countries, covering together 83% of the European organically managed horticultural area, we calculated approximately 3258 t copper metal per year are consumed by organic agriculture, equalling to 53% of the permitted annual dosage. This amount is split between olives (1263 t y-1, 39%), grapevine (990t y-1, 30%), and almonds (317 t y-1, 10%), followed by other crops with much smaller annual uses (<80 t y-1). Potato, usually considered a highly demanding plant for copper inputs, only uses 39 t y-1 of copper per year. In 56% of the allowed cases (countries × crops), farmers use less than half of the allowed amount, and in 27% less than a quarter, with some variability between countries. Considering the large volumes of copper used annually, replacement of copper seems only feasible if all preventive strategies from the crop protection pyramid are fully implemented and several affordable alternative plant protection products are successfully brought to the market.