scholarly journals Enantiomeric Fractionation during Biotransformation of Chiral Pharmaceuticals in Recirculating Water-Sediment Test Flumes

2020 ◽  
Vol 54 (12) ◽  
pp. 7291-7301 ◽  
Author(s):  
Jonas Mechelke ◽  
Dominique Rust ◽  
Anna Jaeger ◽  
Juliane Hollender
2020 ◽  
Vol 7 (2) ◽  
pp. 222-231
Author(s):  
Luky Dharmayanti

Lipstick (Lipstick) is a cosmetic sedan that is used to color the lips with an artistic touch so as to enhance aesthetics in facial makeup. One of the plants that can be used as natural dyes is kelumba keling (Bixa orellana L). Kesumba rivet contains bixsin and nonbixin compounds, which can be used as natural dyes that have the potential as antioxidants. The aim of this study is to utilize kelumba keling as a natural coloring agent in lipstick sedans.Making Keeling keumba seed extract by maceration using 70% ethanol as a solvent. The formulation was made by means of a lipstick base added with variations in the concentration of kesumba keling seed extract 18%, 20%, 22%. Tests carried out on a lipstick sedan made include organoleptic test, irritation test, PH test, melting point test, lipstick sediment test , during storage for 30 days.The results of the test of the lipstick extract of the kesumba rivet seed in the stable orange color organoleptic test can be seen in the irritation test of the non-irritating lipstick sedan, at the melting point test at 51oC for 15 minutes formulation F0, F1, F2, F3 the lipstick made can melt, at Sedian rub test was carried out 5 times basting. In this study it can be concluded that the kesumba keling seed extract can be used as a natural coloring agent in lipstick sedans. Kata Kunci    : Biji Kesumba Keling, Lipstik, Evaluasi lipstik


2017 ◽  
Vol 76 (7) ◽  
pp. 1816-1826 ◽  
Author(s):  
Luong N. Nguyen ◽  
Faisal I. Hai ◽  
James A. McDonald ◽  
Stuart J. Khan ◽  
William E. Price ◽  
...  

This study demonstrates continuous enantiomeric inversion and further biotransformation of chiral profens including ibuprofen, naproxen and ketoprofen by an enzymatic membrane bioreactor (EMBR) dosed with laccase. The EMBR showed non-enantioselective transformations, with high and consistent transformation of both (R)- and (S)-ibuprofen (93 ± 6%, n= 10), but lower removals of both enantiomers of naproxen (46 ± 16%, n= 10) and ketoprofen (48 ± 17%, n= 10). Enantiomeric analysis revealed a bidirectional but uneven inversion of the profens, for example 14% inversion of (R)- to (S)- compared to 4% from (S)- to (R)-naproxen. With redox-mediator addition, the enzymatic chiral inversion of both (R)- and (S)-profens remained unchanged, although the overall conversion became enantioselective; except for (S)-naproxen, the addition of redox mediator promoted the degradation of (R)-profens only.


Author(s):  
Blake J. Landry ◽  
Yovanni A. Catan˜o-Lopera ◽  
Matthew J. Hancock ◽  
Chiang C. Mei ◽  
Marcelo H. Garci´a

Laboratory experiments analyzed herein focus on the validity of ripple predictors under spatially variable wave envelopes. Present-day ripple predictors commonly derived from laboratory data (for smaller wave periods of about 1 to 4 s) within which only small regions of the facilities were used to observe and measure the sand ripple geometric characteristics of the nearly progressive waves measured overhead. When extended to large sediment test sections, our results show that the predictors are still valid along the tank under wave conditions which have significant wave envelope spatial variation (e.g., standing waves), provided that ripple predictors use the wave measurements directly above the respective locations within the computations. Results indicate that even under the case of mild reflection, noticeable variation in ripple characteristics can be seen along the sediment test section; thus, compels the necessity of measuring the wave field along the entire sediment section to achieve accurate results.


1960 ◽  
Vol 43 (3) ◽  
pp. 576-579
Author(s):  
Curtis R Joiner
Keyword(s):  

2020 ◽  
Vol 394 ◽  
pp. 122589 ◽  
Author(s):  
Yuefei Ruan ◽  
Huiju Lin ◽  
Xiaohua Zhang ◽  
Rongben Wu ◽  
Kai Zhang ◽  
...  

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