Label-Free Electrical Immunosensor for Highly Sensitive and Specific Detection of Microcystin-LR in Water Samples

2015 ◽  
Vol 49 (15) ◽  
pp. 9256-9263 ◽  
Author(s):  
Feng Tan ◽  
Nuvia Maria Saucedo ◽  
Pankaj Ramnani ◽  
Ashok Mulchandani
The Analyst ◽  
2016 ◽  
Vol 141 (5) ◽  
pp. 1822-1829 ◽  
Author(s):  
Jie Hu ◽  
Qianfen Zhuang ◽  
Yong Wang ◽  
Yongnian Ni

The synergistically enhanced catalytic effect of a Fe2+/molybdenum disulfide (MoS2) nanosheet was exploited to construct a nanozyme biosensor for Fe2+.


2015 ◽  
Vol 7 (13) ◽  
pp. 5600-5605 ◽  
Author(s):  
Bingfang Shi ◽  
Yingfeng Qin ◽  
Mengjiao Huang ◽  
Jingjin Zhao ◽  
Yubin Su ◽  
...  

A label-free colorimetric assay based on the catalysis of G-quadruplex/hemin DNAzyme was developed for highly sensitive and specific detection of S1 nuclease activity and inhibition.


2021 ◽  
Vol 93 (5) ◽  
pp. 2982-2987
Author(s):  
Shan Zhou ◽  
Liping Zhang ◽  
Lei Xie ◽  
Jie Zeng ◽  
Beilei Qiu ◽  
...  

Micromachines ◽  
2021 ◽  
Vol 12 (2) ◽  
pp. 147
Author(s):  
Kristina A. Malsagova ◽  
Tatyana O. Pleshakova ◽  
Vladimir P. Popov ◽  
Igor N. Kupriyanov ◽  
Rafael A. Galiullin ◽  
...  

Gas-phase etching and optical lithography were employed for the fabrication of a silicon nanoribbon chip (Si-NR chip). The quality of the so-fabricated silicon nanoribbons (Si-NRs) was monitored by optical Raman scattering spectroscopy. It was demonstrated that the structures of the Si-NRs were virtually defect-free, meaning they could be used for highly sensitive detection of biological macromolecules. The Si-NR chips were then used for the highly sensitive nanoelectronics detection of DNA oligonucleotides (oDNAs), which represent synthetic analogs of 106a-5p microRNA (miR-106a-5p), associated with the development of autism spectrum disorders in children. The specificity of the analysis was attained by the sensitization of the Si-NR chip sur-face by covalent immobilization of oDNA probes, whose nucleotide sequence was complementary to the known sequence of miR-106a-5p. The use of the Si-NR chip was demonstrated to al-low for the rapid label-free real-time detection of oDNA at ultra-low (~10−17 M) concentrations.


2021 ◽  
Vol 6 (1) ◽  
pp. 26
Author(s):  
Rahat Morad Talukder ◽  
Al Shahriar Hossain Rakib ◽  
Julija Skolnik ◽  
Zohair Usfoor ◽  
Katharina Kaufmann ◽  
...  

In a series of recently published works, we demonstrated that the plasmon-assisted microscopy of nano-objects (PAMONO) technique can be successfully employed for the sizing and quantification of single viruses, virus-like particles, microvesicles and charged non-biological particles. This approach enables label-free, but specific detection of biological nano-vesicles. Hence, the sensor, which was built up utilizing plasmon-assisted microscopy, possesses relative versatility and it can be used as a platform for cell-based assays. However, one of the challenging tasks for such a sensor was the ability to reach a homogeneous illumination of the whole surface of the gold sensor slide. Moreover, in order to enable the detection of even relatively low concentrations of nano-particles, the focused image area had to be expanded. Both tasks were solved via modifications of previously described PAMONO-sensor set ups. Taken together, our latest findings can help to develop a research and diagnostic platform based on the principles of the surface plasmon resonance (SPR)-assisted microscopy of nano-objects.


2019 ◽  
Vol 42 (17) ◽  
pp. 2851-2857 ◽  
Author(s):  
Xuemei Wang ◽  
Haixia Kou ◽  
Juan Wang ◽  
Tongtong Du ◽  
Ruiju Teng ◽  
...  

2017 ◽  
Vol 35 (22) ◽  
pp. 4851-4858 ◽  
Author(s):  
Mohamed Farhat O. Hameed ◽  
Ahmed Samy Saadeldin ◽  
Essam M. A. Elkaramany ◽  
Salah S. A. Obayya

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