Field Evaluation of a Potential Exposure Biomarker of Methylated Polycyclic Aromatic Hydrocarbons: Association between Urinary Phenanthrene-2-carboxylic Acid and Personal Exposure to 2-Methylphenanthrene

2022 ◽  
Author(s):  
Yan Lin ◽  
Hanxiyue Zhang ◽  
Yiqun Han ◽  
Xinghua Qiu ◽  
Xing Jiang ◽  
...  
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Carboxylic Acid ◽  
Aromatic Hydrocarbons ◽  
Field Evaluation ◽  
Personal Exposure ◽  
Potential Exposure ◽  
Exposure Biomarker ◽  
Polycyclic Aromatic

scholarly journals Exposure to Atmospheric Particulate Matter-Bound Polycyclic Aromatic Hydrocarbons and Their Health Effects: A Review

2021 ◽  
Vol 18 (4) ◽  
pp. 2177
Author(s):  
Lu Yang ◽  
Hao Zhang ◽  
Xuan Zhang ◽  
Wanli Xing ◽  
Yan Wang ◽  
...  
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Particulate Matter ◽  
Real Time ◽  
Health Effects ◽  
Aromatic Hydrocarbons ◽  
Anthropogenic Activities ◽  
Personal Exposure ◽  
Epidemiological Studies ◽  
Atmospheric Particulate Matter ◽  
Polycyclic Aromatic

Particulate matter (PM) is a major factor contributing to air quality deterioration that enters the atmosphere as a consequence of various natural and anthropogenic activities. In PM, polycyclic aromatic hydrocarbons (PAHs) represent a class of organic chemicals with at least two aromatic rings that are mainly directly emitted via the incomplete combustion of various organic materials. Numerous toxicological and epidemiological studies have proven adverse links between exposure to particulate matter-bound (PM-bound) PAHs and human health due to their carcinogenicity and mutagenicity. Among human exposure routes, inhalation is the main pathway regarding PM-bound PAHs in the atmosphere. Moreover, the concentrations of PM-bound PAHs differ among people, microenvironments and areas. Hence, understanding the behaviour of PM-bound PAHs in the atmosphere is crucial. However, because current techniques hardly monitor PAHs in real-time, timely feedback on PAHs including the characteristics of their concentration and composition, is not obtained via real-time analysis methods. Therefore, in this review, we summarize personal exposure, and indoor and outdoor PM-bound PAH concentrations for different participants, spaces, and cities worldwide in recent years. The main aims are to clarify the characteristics of PM-bound PAHs under different exposure conditions, in addition to the health effects and assessment methods of PAHs.

Personal Exposure of Children to Particle-Associated Polycyclic Aromatic Hydrocarbons in Tianjin, China

2014 ◽  
Vol 34 (4) ◽  
pp. 320-342 ◽  
Author(s):  
Jinbao Han ◽  
Nan Zhang ◽  
Can Niu ◽  
Bin Han ◽  
Zhipeng Bai
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Aromatic Hydrocarbons ◽  
Personal Exposure ◽  
Polycyclic Aromatic

scholarly journals Identification of a Novel Metabolite in the Degradation of Pyrene by Mycobacterium sp. Strain AP1: Actions of the Isolate on Two- and Three-Ring Polycyclic Aromatic Hydrocarbons

2001 ◽  
Vol 67 (12) ◽  
pp. 5497-5505 ◽  
Author(s):  
Joaquim Vila ◽  
Zaira López ◽  
Jordi Sabaté ◽  
Cristina Minguillón ◽  
Anna M. Solanas ◽  
...  
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Carboxylic Acid ◽  
Dicarboxylic Acid ◽  
Aromatic Hydrocarbons ◽  
Environmental Fate ◽  
Sole Source ◽  
Bacterial Strains ◽  
Polycyclic Aromatic ◽  
Insight Into

ABSTRACT Mycobacterium sp. strain AP1 grew with pyrene as a sole source of carbon and energy. The identification of metabolites accumulating during growth suggests that this strain initiates its attack on pyrene by either monooxygenation or dioxygenation at its C-4, C-5 positions to give trans- orcis-4,5-dihydroxy-4,5-dihydropyrene, respectively. Dehydrogenation of the latter, ortho cleavage of the resulting diol to form phenanthrene 4,5-dicarboxylic acid, and subsequent decarboxylation to phenanthrene 4-carboxylic acid lead to degradation of the phenanthrene 4-carboxylic acid via phthalate. A novel metabolite identified as 6,6′-dihydroxy-2,2′-biphenyl dicarboxylic acid demonstrates a new branch in the pathway that involves the cleavage of both central rings of pyrene. In addition to pyrene, strain AP1 utilized hexadecane, phenanthrene, and fluoranthene for growth. Pyrene-grown cells oxidized the methylenic groups of fluorene and acenaphthene and catalyzed the dihydroxylation andortho cleavage of one of the rings of naphthalene and phenanthrene to give 2-carboxycinnamic and diphenic acids, respectively. The catabolic versatility of strain AP1 and its use ofortho cleavage mechanisms during the degradation of polycyclic aromatic hydrocarbons (PAHs) give new insight into the role that pyrene-degrading bacterial strains may play in the environmental fate of PAH mixtures.

scholarly journals Relation between personal exposure and outdoor concentrations of carcinogenic polycyclic aromatic hydrocarbons during smog episode

2019 ◽  
Vol 27 (4) ◽  
pp. 305-311
Author(s):  
Vlasta Švecová ◽  
Jan Topinka ◽  
Ivo Solanský ◽  
David Broday ◽  
Radim J. Šrám
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Aromatic Hydrocarbons ◽  
Personal Exposure ◽  
Polycyclic Aromatic
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