High Value-Added Application of Natural Products in Crop Protection: Semisynthesis and Acaricidal Activity of Limonoid-Type Derivatives and Investigation of Their Biocompatible O/W Nanoemulsions as Agronanopesticide Candidates

Author(s):  
Xiaobo Huang ◽  
Min Lv ◽  
Qianjun Ma ◽  
Yuanyuan Zhang ◽  
Hui Xu
Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381 ◽  
Author(s):  
A Bruguière ◽  
AM Le Ray ◽  
D Bréard ◽  
N Blon ◽  
N Bataillé ◽  
...  

ChemInform ◽  
2011 ◽  
Vol 42 (32) ◽  
pp. no-no
Author(s):  
Carl F. Nising ◽  
Stefan Hillebrand ◽  
Lars Rodefeld

Genome ◽  
2013 ◽  
Vol 56 (11) ◽  
pp. 677-689 ◽  
Author(s):  
Xiang-Jing Wang ◽  
Bo Zhang ◽  
Yi-Jun Yan ◽  
Jing An ◽  
Ji Zhang ◽  
...  

Streptomyces bingchenggensis is a soil bacterium that produces milbemycins, a family of macrolide antibiotics that are commercially important in crop protection and veterinary medicine. In addition, S. bingchenggensis produces many other natural products including the polyether nanchangmycin and novel cyclic pentapeptides. To identify the gene clusters involved in the biosynthesis of these compounds, and better clarify the biochemical pathways of these gene clusters, the whole genome of S. bingchenggensis was sequenced, and the transcriptome profile was subsequently investigated by microarray. In comparison with other sequenced genomes in Streptomyces, S. bingchenggensis has the largest linear chromosome consisting of 11 936 683 base pairs (bp), with an average GC content of 70.8%. The 10 023 predicted protein-coding sequences include at least 47 gene clusters correlated with the biosynthesis of known or predicted secondary metabolites. Transcriptional analysis demonstrated an extremely high expression level of the milbemycin gene cluster during the entire growth period and a moderately high expression level of the nanchangmycin gene cluster during the initial hours that subsequently decreased. However, other gene clusters appear to be silent. The genome-wide analysis of the secondary metabolite gene clusters in S. bingchenggensis, coupled with transcriptional analysis, will facilitate the rational development of high milbemycins-producing strains as well as the discovery of new natural products.


2018 ◽  
Vol 2 (3) ◽  
pp. 389-403 ◽  
Author(s):  
Ramesh Prasad Pandey ◽  
Prakash Parajuli ◽  
Jae Kyung Sohng

Microbial cell factories are extensively used for the biosynthesis of value-added chemicals, biopharmaceuticals, and biofuels. Microbial biosynthesis is also realistic for the production of heterologous molecules including complex natural products of plant and microbial origin. Glycosylation is a well-known post-modification method to engineer sugar-functionalized natural products. It is of particular interest to chemical biologists to increase chemical diversity of molecules. Employing the state-of-the-art systems and synthetic biology tools, a range of small to complex glycosylated natural products have been produced from microbes using a simple and sustainable fermentation approach. In this context, this review covers recent notable metabolic engineering approaches used for the biosynthesis of glycosylated plant and microbial polyketides in different microorganisms. This review article is broadly divided into two major parts. The first part is focused on the biosynthesis of glycosylated plant polyketides in prokaryotes and yeast cells, while the second part is focused on the generation of glycosylated microbial polyketides in actinomycetes.


Molecules ◽  
2021 ◽  
Vol 26 (21) ◽  
pp. 6539
Author(s):  
Hlabana A. Seepe ◽  
Winston Nxumalo ◽  
Stephen O. Amoo

Many Fusarium species are pathogenic, causing crop diseases during crop production and spoilage of agricultural products in both commercial and smallholder farming. Fusarium attack often results into food contamination, yield loss and increases in food insecurity and food prices. Synthetic fungicides have been used as a control strategy for the management of crop diseases caused by Fusarium pathogens. The negative effects associated with application of many synthetic pesticides has necessitated the need to search for alternative control strategies that are affordable and environmentally safe. Research on medicinal plants as control agents for Fusarium pathogens has received attention since plants are readily available and they contain wide variety of secondary metabolites that are biodegradable. The activities of solvent extracts, essential oils and compounds from medicinal plants have been tested against Fusarium phytopathogenic species. A summary of recent information on antifungal activity of plants against Fusarium species is valuable for the development of biopesticides. This paper reviews the antifungal research conducted on medicinal plants against Fusarium pathogens, over a 10-year period, from January 2012 to May 2021. We also highlight the challenges and opportunities of using natural products from medicinal plants in crop protection. Several databases (Science Direct and Web of Science) were used to obtain information on botanical products used to control Fusarium diseases on crops. Keywords search used included natural products, antifungal, Fusarium, crops diseases, phytopathogenic, natural compounds and essential oil.


MAUSAM ◽  
2021 ◽  
Vol 67 (1) ◽  
pp. 267-276
Author(s):  
AMRENDER KUMAR ◽  
A. K. JAIN ◽  
B. K. BHATTACHARYA ◽  
VINOD KUMAR ◽  
A. K. MISHRA ◽  
...  

Models are means to capture, condense and organize knowledge. These are expressions, which represent relationship between various components of a system. A well-tested weather-based model can be an effective scientific tool for forewarning insect-pests and diseases in advance so that timely plant protection measures could be taken up. Various types of techniques have been developed for the purpose. The simplest technique forms the class of thumb rules, which are based on experience. Though these do not have much scientific background but are extensively used to provide quick forewarning of the menace. Another tool in practice is regression model that represents relationship between two or more variables so that one variable can be predicted from the other (s). Linear and non-linear regression models have been widely used in studying relationship of insect-pests and diseases with time and weather variables (as such or in some transformed forms). With the advent of computers more sophisticated techniques such as simulation modelling and machine learning approach such as decision tree induction algorithms, genetic algorithms, neural networks, rough sets, etc. have been explored. A number of simulation models have been developed all over the world for quantifying effects of various factors including weather on agriculture.  These may provide a good forecast but require detailed data base, which may not be available. Machine learning approach has recently received some attention. As opposed to traditional model-based methods, machine learning approach is self adaptive methods in that there are a few a priori assumptions about the models for problem(s) under study. This technique learns more from examples and captures subtle functional relationships among the data even if the underlying relationships are unknown or hard to describe.  This modelling approach with ability to learn from experience is very useful for many practical problems provided enough data are available. Remotely sensed data can provide useful information relating to area under the crop and also the condition thereof. It has certain advantages over land use statistics due to multi-spectral, synoptic and repetitive coverage. An attempt has been made for accurate estimation of area affected by insect-pests and diseases in crops along with accurate assessment of damage due to the same are possible for providing compensation to farmers. In this study, an Integrated Decision Support System (IDSS) for Crop Protection Services is also discussed.  


2010 ◽  
Vol 10 (2) ◽  
pp. 195-195
Author(s):  
Ottmar Franz Hüter

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