scholarly journals ChemBioSim: Enhancing Conformal Prediction of In Vivo Toxicity by Use of Predicted Bioactivities

2021 ◽  
Author(s):  
Marina Garcia de Lomana ◽  
Andrea Morger ◽  
Ulf Norinder ◽  
Roland Buesen ◽  
Robert Landsiedel ◽  
...  
Keyword(s):  
Conformal Prediction ◽  
In Vivo Toxicity

NT4X-167; Novel N-terminal Aβ specific antibody, prevents in vitro and in vivo toxicity of highly toxic Aβ4-42 species

2015 ◽  
Vol 48 (06) ◽  
Author(s):  
G Antonios ◽  
H Borgers ◽  
T Pilot ◽  
V Pena ◽  
T Bayer
Keyword(s):  
Specific Antibody ◽  
In Vivo Toxicity

Negative cross resistance of Spodoptera litura Fabricius population of tomato to newer molecule spinetoram

ENTOMON ◽  
2019 ◽  
Vol 44 (2) ◽  
pp. 127-132
Author(s):  
M. Visnupriya ◽  
N. Muthukrishnan
Keyword(s):  
Spodoptera Litura ◽  
Laboratory Strain ◽  
Field Population ◽  
Resistance Ratio ◽  
Cross Resistance ◽  
In Vivo Toxicity

Field population of Spodoptera litura from tomato ( resistant to the majority of the conventional insecticide molecules) were subjected to the in vivo toxicity of spinetoram 12 SC to assess whether cross resistance exists or not. Untreated larvae of both field and laboratory strains showed no mortality during 48 hours of feeding. After 48 hours of feeding on spinetoram 12 SC treated leaves, LC50s of field larvae were 0.28, 0.93, 3.71 and 7.11 ppm for the 2nd, 3rd, 4th and 5th instars of S. litura respectively. However, in the laboratory strain these values were 1.12, 5.86, 36.72 and 91.55 ppm for 2nd, 3rd, 4th and 5th instars of S. litura respectively. Resistance ratio was 0.25, 0.16, 0.10 and 0.08 for the 2nd instar up to the 5th instar of S. litura.

Mixed Micelles as Nano Polymer Therapeutics of Docetaxel: Increased In vitro Cytotoxicity and Decreased In vivo Toxicity

2018 ◽  
Vol 15 (4) ◽  
pp. 564-575 ◽  
Author(s):  
Arehalli S. Manjappa ◽  
Popat S. Kumbhar ◽  
Prajakta S. Khopade ◽  
Ajit B. Patil ◽  
John I. Disouza
Keyword(s):  
Mixed Micelles ◽  
In Vitro Cytotoxicity ◽  
Polymer Therapeutics ◽  
In Vivo Toxicity

Larvicidal activity, aquatic and in vivo toxicity of anacardic acid loaded-zein nanoparticles

2021 ◽  
Vol 63 ◽  
pp. 102513
Author(s):  
Eduardo Júnior Serrão Pinto ◽  
Jennifer Thayanne Cavalcante de Araujo ◽  
Ricardo Marcelo dos Anjos Ferreira ◽  
Raimundo Nonato Picanço Souto ◽  
Laís Aragão Lima ◽  
...  
Keyword(s):  
Larvicidal Activity ◽  
Anacardic Acid ◽  
In Vivo Toxicity

Book Review: Handbook of In Vivo Toxicity Testing

1990 ◽  
Vol 18 (1_part_1) ◽  
pp. 354-355
Author(s):  
Ralph Heywood
Keyword(s):  
Toxicity Testing ◽  
In Vivo Toxicity

Toxico-metabolomics study of a deep eutectic solvent comprising choline chloride and urea suggests in vivo toxicity involving oxidative stress and ammonia stress

2021 ◽  
Vol 23 (3) ◽  
pp. 1300-1311 ◽  
Author(s):  
Dasom Jung ◽  
Jae Back Jung ◽  
Seulgi Kang ◽  
Ke Li ◽  
Inseon Hwang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Choline Chloride ◽  
Deep Eutectic Solvent ◽  
Deep Eutectic Solvents ◽  
In Vivo Toxicity ◽  
Metabolomics Study ◽  
Ammonia Stress

The in vitro and in vivo studies suggest that choline chloride-based deep eutectic solvents may not be considered as pure, safe mixtures even if they consist of safe compounds.

scholarly journals Aedes cadherin mediates the in vivo toxicity of the Cry11Aa toxin to Aedes aegypti

Peptides ◽  
2015 ◽  
Vol 68 ◽  
pp. 140-147 ◽  
Author(s):  
Su-Bum Lee ◽  
Jianwu Chen ◽  
Karlygash G. Aimanova ◽  
Sarjeet S. Gill
Keyword(s):  
Aedes Aegypti ◽  
In Vivo Toxicity

Effect of tocopherol on the properties of Pluronic F127 microemulsions: Physico-chemical characterization and in vivo toxicity

2019 ◽  
Vol 277 ◽  
pp. 624-630 ◽  
Author(s):  
Addas Rahdar ◽  
Pablo Taboada ◽  
Mohammad Reza Hajinezhad ◽  
Mahmood Barani ◽  
Hamid Beyzaei
Keyword(s):  
Chemical Characterization ◽  
Pluronic F127 ◽  
In Vivo Toxicity ◽  
Physico Chemical

scholarly journals High-efficiency liposomal encapsulation of a tyrosine kinase inhibitor leads to improved in vivo toxicity and tumor response profile

2013 ◽  
pp. 3991 ◽  
Author(s):  
Milan Makale ◽  
Rajesh Mukthavaram ◽  
Pengfei Jiang ◽  
Rohit Saklecha ◽  
Dmitri Simberg ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
High Efficiency ◽  
Tumor Response ◽  
Kinase Inhibitor ◽  
In Vivo Toxicity ◽  
Response Profile
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