Engineered Human Adipose Stem-Cell-Derived Exosomes Loaded with miR-21-5p to Promote Diabetic Cutaneous Wound Healing

2020 ◽  
Vol 17 (5) ◽  
pp. 1723-1733 ◽  
Author(s):  
Qijun Lv ◽  
Junfeng Deng ◽  
You Chen ◽  
Yizhen Wang ◽  
Bo Liu ◽  
...  
Keyword(s):  
Wound Healing ◽  
Stem Cell ◽  
Cutaneous Wound Healing ◽  
Adipose Stem Cell ◽  
Cutaneous Wound ◽  
Human Adipose Stem Cell

Combined Gene and Stem Cell Therapy for Cutaneous Wound Healing

2011 ◽  
Vol 8 (5) ◽  
pp. 1471-1479 ◽  
Author(s):  
Gerd G. Gauglitz ◽  
Marc G. Jeschke
Keyword(s):  
Wound Healing ◽  
Stem Cell ◽  
Cell Therapy ◽  
Stem Cell Therapy ◽  
Cutaneous Wound Healing ◽  
Cutaneous Wound

scholarly journals Advances of Stem Cell Therapeutics in Cutaneous Wound Healing and Regeneration

2017 ◽  
Vol 2017 ◽  
pp. 1-14 ◽  
Author(s):  
Suman Kanji ◽  
Hiranmoy Das
Keyword(s):  
Stem Cells ◽  
Wound Healing ◽  
Stem Cell ◽  
Wound Repair ◽  
Chronic Wounds ◽  
Healing Process ◽  
Treatment Modalities ◽  
Wound Healing Process ◽  
Cutaneous Wound Healing ◽  
Cutaneous Wound

Cutaneous wound healing is a complex multiple phase process, which overlaps each other, where several growth factors, cytokines, chemokines, and various cells interact in a well-orchestrated manner. However, an imbalance in any of these phases and factors may lead to disruption in harmony of normal wound healing process, resulting in transformation towards chronic nonhealing wounds and abnormal scar formation. Although various therapeutic interventions are available to treat chronic wounds, current wound-care has met with limited success. Progenitor stem cells possess potential therapeutic ability to overcome limitations of the present treatments as it offers accelerated wound repair with tissue regeneration. A substantial number of stem cell therapies for cutaneous wounds are currently under development as a result of encouraging preliminary findings in both preclinical and clinical studies. However, the mechanisms by which these stem cells contribute to the healing process have yet to be elucidated. In this review, we emphasize on the major treatment modalities currently available for the treatment of the wound, role of various interstitial stem cells and exogenous adult stem cells in cutaneous wound healing, and possible mechanisms involved in the healing process.

scholarly journals A review of gene and stem cell therapy in cutaneous wound healing

Burns ◽  
2009 ◽  
Vol 35 (2) ◽  
pp. 171-180 ◽  
Author(s):  
Ludwik K. Branski ◽  
Gerd G. Gauglitz ◽  
David N. Herndon ◽  
Marc G. Jeschke
Keyword(s):  
Wound Healing ◽  
Stem Cell ◽  
Cell Therapy ◽  
Stem Cell Therapy ◽  
Cutaneous Wound Healing ◽  
Cutaneous Wound

scholarly journals Delayed Cutaneous Wound Healing and Aberrant Expression of Hair Follicle Stem Cell Markers in Mice Selectively Lacking Ctip2 in Epidermis

PLoS ONE ◽  
2012 ◽  
Vol 7 (2) ◽  
pp. e29999 ◽  
Author(s):  
Xiaobo Liang ◽  
Shreya Bhattacharya ◽  
Gaurav Bajaj ◽  
Gunjan Guha ◽  
Zhixing Wang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Stem Cell ◽  
Hair Follicle ◽  
Stem Cell Markers ◽  
Cutaneous Wound Healing ◽  
Aberrant Expression ◽  
Cutaneous Wound ◽  
Cell Markers ◽  
Hair Follicle Stem Cell

Embryonic stem cell-derived M2-like macrophages delay cutaneous wound healing

2012 ◽  
Vol 21 (1) ◽  
pp. 44-54 ◽  
Author(s):  
Daniela Dreymueller ◽  
Bernd Denecke ◽  
Andreas Ludwig ◽  
Willi Jahnen-Dechent
Keyword(s):  
Wound Healing ◽  
Stem Cell ◽  
Embryonic Stem Cell ◽  
Embryonic Stem ◽  
Cutaneous Wound Healing ◽  
Cutaneous Wound
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