Self-Assembled DNA Nanostructures-Based Nanocarriers Enabled Functional Nucleic Acids Delivery

2020 ◽  
Vol 3 (5) ◽  
pp. 2779-2795 ◽  
Author(s):  
Jin Huang ◽  
Wenjie Ma ◽  
Huanhuan Sun ◽  
Huizhen Wang ◽  
Xiaoxiao He ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Dna Nanostructures ◽  
Self Assembled ◽  
Nucleic Acids Delivery ◽  
Functional Nucleic Acids

Functional nucleic acids tailoring and its application

2019 ◽  
Vol 118 ◽  
pp. 138-157 ◽  
Author(s):  
Xingning Xiao ◽  
Longjiao Zhu ◽  
Wanchong He ◽  
Yunbo Luo ◽  
Wentao Xu
Keyword(s):  
Nucleic Acids ◽  
Functional Nucleic Acids

Functional nucleic acids for cancer theranostics

2020 ◽  
Vol 403 ◽  
pp. 213080 ◽  
Author(s):  
Tianhuan Peng ◽  
Zhengyu Deng ◽  
Jiaxuan He ◽  
Yingying Li ◽  
Yan Tan ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Cancer Theranostics ◽  
Functional Nucleic Acids

Self-assembled biosensor with universal reporter and dual-quenchers for detection of unlabelled nucleic acids

The Analyst ◽  
2016 ◽  
Vol 141 (4) ◽  
pp. 1376-1382 ◽  
Author(s):  
Liming Huang ◽  
Gyan H. Aryal ◽  
Suk-Wah Tam-Chang ◽  
Nelson G. Publicover ◽  
Kenneth W. Hunter
Keyword(s):  
Nucleic Acids ◽  
Selective Detection ◽  
Self Assembled

We developed a self-assembled biosensor for rapid, sensitive, and selective detection of unlabeled nucleic acids.

scholarly journals Mesoporous Silica Nanoparticles Based Antigens and Nucleic Acids Delivery: A Review

1970 ◽  
Vol 8 (2) ◽  
pp. 50-57
Author(s):  
Jemal Dilebo
Keyword(s):  
Mesoporous Silica ◽  
Nucleic Acids ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Mesoporous Structure ◽  
Nucleic Acid Delivery ◽  
Hollow Core ◽  
Small Molecule Drugs ◽  
Cell Accumulation ◽  
Nucleic Acids Delivery

Mesoporous silica nanoparticles (MSN) have been explored for the delivery of small molecule drugs, antigens, and nucleic acids because of their large surface area, pore volume, amenability of their surface for functionalization, stable mesoporous structure, and biocompatibility.  Biomoecules loading capacitites,  release and target cell accumulation efficiencies have been improved for both antigen and nucleic acid delivery by the synthesis of large-pore MSN, dendritic MSN, hollow-core MSN, and multifunctional MSN. This article overview the major advances in the use of MSN for delivery of antigens and therapeutic nucleic acids such as DNA, siRNA, and miRNA aimed for treatment of various diseases.       

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