High-Density Three-Dimensional Network of Covalently Linked Nitric Oxide Donors to Achieve Antibacterial and Antibiofilm Surfaces

2021 ◽  
Author(s):  
Liping Wang ◽  
Zheng Hou ◽  
Dicky Pranantyo ◽  
En-Tang Kang ◽  
Mary Chan-Park
Keyword(s):  
Nitric Oxide ◽  
Three Dimensional ◽  
High Density ◽  
Nitric Oxide Donors ◽  
Dimensional Network ◽  
Covalently Linked

scholarly journals The Nitric Oxide DonorS-Nitrosoglutathione Reduces Apoptotic Primary Liver Cell Loss in a Three-Dimensional Perfusion Bioreactor Culture Model Developed for Liver Support

2010 ◽  
Vol 16 (3) ◽  
pp. 861-866 ◽  
Author(s):  
Jose M. Prince ◽  
Yoram Vodovotz ◽  
Matthew J. Baun ◽  
Satdarshan Pal Monga ◽  
Timothy R. Billiar ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Liver Cell ◽  
Three Dimensional ◽  
Cell Loss ◽  
Nitric Oxide Donors ◽  
Perfusion Bioreactor ◽  
Bioreactor Culture ◽  
Liver Support ◽  
Culture Model

scholarly journals Crystal structures of two mixed-valence copper cyanide complexes withN-methylethylenediamine

2017 ◽  
Vol 73 (2) ◽  
pp. 141-146 ◽  
Author(s):  
Peter W. R. Corfield ◽  
Alexander Sabatino
Keyword(s):  
Crystal Structures ◽  
Close Contact ◽  
Mixed Valence ◽  
Three Dimensional ◽  
Molecular Compound ◽  
Compound I ◽  
Copper Cyanide ◽  
Dimensional Network ◽  
Covalently Linked ◽  
Compound Ii

The crystal structures of two mixed-valence copper cyanide compounds involvingN-methylethylenediamine (meen), are described. In compound (I), poly[bis(μ3-cyanido-κ3C:C:N)tris(μ2-cyanido-κ2C:N)bis(N-methylethane-1,2-diamine-κ2N,N′)tricopper(I)copper(II)], [Cu4(CN)5(C3H10N2)2] or Cu4(CN)5meen2, cyanide groups link CuIatoms into a three-dimensional network containing open channels parallel to thebaxis. In the network, two tetrahedrally bound CuIatoms are bonded by the C atoms of two end-on bridging CN groups to form Cu2(CN)6moieties with the Cu atoms in close contact at 2.560 (1) Å. Other trigonally bound CuIatoms link these units together to form the network. The CuIIatoms, coordinated by two meen units, are covalently linked to the networkviaa cyanide bridge, and project into the open network channels. In the molecular compound (II), [(N-methylethylenediamine-κ2N,N′)copper(II)]-μ2-cyanido-κ2C:N-[bis(cyanido-κC)copper(I)] monohydrate, [Cu2(CN)3(C3H10N2)2]·H2O or Cu2(CN)3meen2·H2O, a CN group connects a CuIIatom coordinated by two meen groups with a trigonal–planar CuIatom coordinated by CN groups. The molecules are linked into centrosymmetric dimersviahydrogen bonds to two water molecules. In both compounds, the bridging cyanide between the CuIIand CuIatoms has the N atom bonded to CuIIand the C atom bonded to CuI, and the CuIIatoms are in a square-pyramidal coordination.

Immune response via interacting three dimensional network of cellular automata

1989 ◽  
Vol 50 (1) ◽  
pp. 1-10 ◽  
Author(s):  
R.B. Pandey ◽  
D. Stauffer
Keyword(s):  
Immune Response ◽  
Cellular Automata ◽  
Three Dimensional ◽  
Dimensional Network

Activation of TRPV1 by Nitric Oxide Donors Requires Co-Application of Sulfhydryl-Containing Reagent

2018 ◽  
Vol 9 (1) ◽  
pp. 37-46
Author(s):  
Bizhan R. Sharopov ◽  
Yaroslav M. Shuba
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Donors

Development of Mucoadhesive Buccal Drug Delivery System of Propranolol Hydrochloride Using Aster ericoides Mucilage

2020 ◽  
Vol 10 (2) ◽  
pp. 133-148
Author(s):  
Ankaj Kaundal ◽  
Pravin Kumar ◽  
Rajendra Awasthi ◽  
Giriraj T. Kulkarni
Keyword(s):  
Buccal Cavity ◽  
Three Dimensional ◽  
Hot Water ◽  
Fickian Diffusion ◽  
Aster Ericoides ◽  
Dimensional Network ◽  
Buccal Tablet ◽  
Significant Difference ◽  
Volunteer Group

Aim: The study was aimed to develop mucoadhesive buccal tablets using Aster ericoides leaves mucilage. Background : Mucilages are naturally occurring high-molecular-weight polyuronides, which have been extensively studied for their application in different pharmaceutical dosage forms. Objective: The objective of the present research was to establish the mucilage isolated from the leaves of Aster ericoides as an excipient for the formulation of the mucoadhesive buccal tablet. Method: The mucilage was isolated from the leaves of Aster ericoides by maceration, precipitated with acetone and characterized. Tablets were prepared using wet granulation technique and evaluated for various official tests. Results: The mucilage was found to be non-toxic on A-431 and Vero cell lines. It was insoluble but swellable in cold and hot water. The results indicate that mucilage can form a three-dimensional network. The pH of the mucilage (6.82 ± 0.13) indicated that it might be non-irritant to the buccal cavity. The mucilage was found to be free from microbes. The release of drug was by Fickian diffusion. The in vivo buccal tablet acceptance was 80%. No significant difference between the diastolic blood pressure of standard and Aster tablets treated volunteer group was recorded. Conclusion: The mucilage was found to be non-toxic on A-431 and Vero cell lines. It was insoluble but swellable in cold and hot water. The results indicate that mucilage can form a three-dimensional network. The pH of the mucilage (6.82 ± 0.13) indicated that it might be non-irritant to the buccal cavity. The mucilage was found to be free from microbes. The release of drug was by Fickian diffusion. The in vivo buccal tablet acceptance was 80%. No significant difference between the diastolic blood pressure of standard and Aster tablets treated volunteer group was recorded. Other: However, to prove the potency of the polymer, in vivo bioavailability studies in human volunteers are needed along with chronic toxicity studies in suitable animal models.

Nitric oxide donors for cervical ripening in first trimester for termination of pregnancy

2008 ◽  
Author(s):  
Patama Promsonthi ◽  
Domerudee Preechapornprasert ◽  
Boonsri Chanrachakul
Keyword(s):  
Nitric Oxide ◽  
First Trimester ◽  
Termination Of Pregnancy ◽  
Cervical Ripening ◽  
Nitric Oxide Donors

scholarly journals Crystal structure of K[Hg(SCN)3] – a redetermination

2014 ◽  
Vol 70 (9) ◽  
pp. i46-i46 ◽  
Author(s):  
Matthias Weil ◽  
Thomas Häusler
Keyword(s):  
Crystal Structure ◽  
Room Temperature ◽  
Three Dimensional ◽  
Lattice Parameters ◽  
Bond Lengths ◽  
Dimensional Network ◽  
Anisotropic Displacement Parameters ◽  
Precision And Accuracy ◽  
Standard Deviations ◽  
Atomic Coordinates

The crystal structure of the room-temperature modification of K[Hg(SCN)3], potassium trithiocyanatomercurate(II), was redetermined based on modern CCD data. In comparison with the previous report [Zhdanov & Sanadze (1952).Zh. Fiz. Khim.26, 469–478], reliability factors, standard deviations of lattice parameters and atomic coordinates, as well as anisotropic displacement parameters, were revealed for all atoms. The higher precision and accuracy of the model is, for example, reflected by the Hg—S bond lengths of 2.3954 (11), 2.4481 (8) and 2.7653 (6) Å in comparison with values of 2.24, 2.43 and 2.77 Å. All atoms in the crystal structure are located on mirror planes. The Hg2+cation is surrounded by four S atoms in a seesaw shape [S—Hg—S angles range from 94.65 (2) to 154.06 (3)°]. The HgS4polyhedra share a common S atom, building up chains extending parallel to [010]. All S atoms of the resulting1∞[HgS2/1S2/2] chains are also part of SCN−anions that link these chains with the K+cations into a three-dimensional network. The K—N bond lengths of the distorted KN7polyhedra lie between 2.926 (2) and 3.051 (3) Å.

scholarly journals Construction of the Cellulose Nanofibers (CNFs) Aerogel Loading TiO2 NPs and Its Application in Disposal of Organic Pollutants

Polymers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1841
Author(s):  
Kang Li ◽  
Xuejie Zhang ◽  
Yan Qin ◽  
Ying Li
Keyword(s):  
High Efficiency ◽  
Sol Gel ◽  
Cellulose Nanofibers ◽  
Three Dimensional ◽  
Good Mechanical Property ◽  
Polar Groups ◽  
Dimensional Network ◽  
Natural Polysaccharide ◽  
Valuable Method ◽  
Adsorption Capability

Aerogels have been widely used in the adsorption of pollutants because of their large specific surface area. As an environmentally friendly natural polysaccharide, cellulose is a good candidate for the preparation of aerogels due to its wide sources and abundant polar groups. In this paper, an approach to construct cellulose nanofibers aerogels with both the good mechanical property and the high pollutants adsorption capability through chemical crosslinking was explored. On this basis, TiO2 nanoparticles were loaded on the aerogel through the sol-gel method followed by the hydrothermal method, thereby the enriched pollutants in the aerogel could be degraded synchronously. The chemical cross-linker not only helps build the three-dimensional network structure of aerogels, but also provides loading sites for TiO2. The degradation efficiency of pollutants by the TiO2@CNF Aerogel can reach more than 90% after 4 h, and the efficiency is still more than 70% after five cycles. The prepared TiO2@CNF Aerogels have high potential in the field of environmental management, because of the high efficiency of treating organic pollutes and the sustainability of the materials. The work also provides a choice for the functional utilization of cellulose, offering a valuable method to utilize the large amount of cellulose in nature.

scholarly journals Enhanced bacterial disinfection by CuI–BiOI/rGO hydrogel under visible light irradiation

RSC Advances ◽  
2021 ◽  
Vol 11 (33) ◽  
pp. 20446-20456
Author(s):  
Xi Ma ◽  
Ziwei Wang ◽  
Haoguo Yang ◽  
Yiqiu Zhang ◽  
Zizhong Zhang ◽  
...  
Keyword(s):  
Electron Transport ◽  
Visible Light ◽  
Network Structure ◽  
Visible Light Irradiation ◽  
Three Dimensional ◽  
Light Irradiation ◽  
Transport Capacity ◽  
Highly Efficient ◽  
Dimensional Network ◽  
Bacterial Disinfection

Compared with traditional layered graphene, graphene hydrogels have been used to construct highly efficient visible light-excited photocatalysts due to their particular three-dimensional network structure and efficient electron transport capacity.

Sign in / Sign up

Export Citation Format

Share Document