A Thrombin-Responsive Nanoprobe for In Vivo Visualization of Thrombus Formation through Three-Dimensional Optical/Computed Tomography Hybrid Imaging

2021 ◽  
Author(s):  
Yabin Wang ◽  
Mengqi Xu ◽  
Ning Yang ◽  
Shan Gao ◽  
Sulei Li ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Hybrid Imaging ◽  
Thrombus Formation ◽  
Three Dimensional ◽  
Optical Computed Tomography

A method for obtaining three-dimensional measurements of HDR brachytherapy dose distributions using Fricke gel dosimeters and optical computed tomography

2018 ◽  
Vol 42 (1) ◽  
pp. 221-226 ◽  
Author(s):  
Andre Asena ◽  
Sanna Nilsson ◽  
Shaun T. Smith ◽  
Tanya Kairn ◽  
Scott B. Crowe ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Three Dimensional ◽  
Hdr Brachytherapy ◽  
Dose Distributions ◽  
Optical Computed Tomography ◽  
Dimensional Measurements

Hybrid imaging (SPECT/computed tomography) with three-dimensional reconstruction: a new diagnostic tool for the study of low back pain after spinal fusion surgery

2015 ◽  
Vol 15 (2) ◽  
pp. 377-378 ◽  
Author(s):  
Estefania López Rodriguez ◽  
Rosario Garcia Jimenez ◽  
Marta Sanchez Aguilar ◽  
Julio Valencia Anguita ◽  
Javier Luis Simon
Keyword(s):  
Computed Tomography ◽  
Low Back Pain ◽  
Back Pain ◽  
Diagnostic Tool ◽  
Hybrid Imaging ◽  
Three Dimensional ◽  
Low Back ◽  
Fusion Surgery ◽  
Spinal Fusion Surgery ◽  
Dimensional Reconstruction

scholarly journals Recent advances in Optical Computed Tomography (OCT) imaging system for three dimensional (3D) radiotherapy dosimetry

2018 ◽  
Vol 298 ◽  
pp. 012036 ◽  
Author(s):  
Ahmad Taufek Abdul Rahman ◽  
Nurul Farah Rosli ◽  
Shafirah Mohd Zain ◽  
Hafiz M. Zin
Keyword(s):  
Computed Tomography ◽  
Imaging System ◽  
Three Dimensional ◽  
Optical Computed Tomography ◽  
Recent Advances ◽  
Oct Imaging ◽  
Radiotherapy Dosimetry ◽  
3D Radiotherapy

Three-dimensional reconstruction based on images from spiral high-resolution computed tomography of the temporal bone: anatomy and clinical application

2005 ◽  
Vol 119 (9) ◽  
pp. 693-698 ◽  
Author(s):  
Beom-Cho Jun ◽  
Sun-Wha Song ◽  
Ju-Eun Cho ◽  
Chan-Soon Park ◽  
Dong-Hee Lee ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
3D Reconstruction ◽  
Temporal Bone ◽  
Three Dimensional ◽  
Image Data ◽  
Computer Assisted ◽  
Surface Rendering ◽  
High Resolution Computed Tomography

The aim of this study was to investigate the usefulness of a three-dimensional (3D) reconstruction of computed tomography (CT) images in determining the anatomy and topographic relationship between various important structures. Using 40 ears from 20 patients with various otological diseases, a 3D reconstruction based on the image data from spiral high-resolution CT was performed by segmentation, volume-rendering and surface-rendering algorithms on a personal computer. The 3D display of the middle and inner ear structures was demonstrated in detail. Computer-assisted measurements, many of which could not be easily measured in vivo, of the reconstructed structures provided accurate anatomic details that improved the surgeon’s understanding of spatial relationships. A 3D reconstruction of temporal bone CT might be useful for education and increasing understanding of the anatomical structures of the temporal bone. However, it will be necessary to confirm the correlation between the 3D reconstructed images and histological sections through a validation study.

scholarly journals Introducing a Novel Method for Three Dimensional Dose Map by Optical Computed Tomography

2016 ◽  
Vol In press (In press) ◽  
Author(s):  
Nooshin Banaee ◽  
Hassan Ali Nedaie ◽  
Alireza Shirazi ◽  
Alireza Zirak ◽  
Sodeh Sadjadi
Keyword(s):  
Computed Tomography ◽  
Three Dimensional ◽  
Optical Computed Tomography ◽  
Novel Method

scholarly journals Optical computed tomography in PRESAGE® three-dimensional dosimetry: challenges and prospective

2017 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
HassanAli Nedaie ◽  
Davood Khezerloo ◽  
Bagher Farhood ◽  
Alireza Zirak ◽  
Abbas Takavar ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Three Dimensional ◽  
Optical Computed Tomography

Percutaneous Tibial Fracture Reduction Using Computed Tomography Imaging, Computer Modelling and 3D Printed Alignment Constructs: A Cadaveric Study

2019 ◽  
Vol 32 (02) ◽  
pp. 139-148 ◽  
Author(s):  
John Davies ◽  
Albert Lynch
Keyword(s):  
Computed Tomography ◽  
Tibial Fracture ◽  
Computer Modelling ◽  
Three Dimensional ◽  
Joint Angles ◽  
In Vivo Evaluation ◽  
Minimally Invasive Osteosynthesis ◽  
Diaphyseal Fractures ◽  
3D Printed

Objective The main aim of this study was to evaluate a percutaneous method of bone alignment using a diaphyseal tibial fracture model. Materials and Methods Mid-shaft diaphyseal fractures were created in 12 large-breed canine tibiae. Interaction pins were inserted into the proximal and distal bone segments. Computed tomography scans of the fractured tibiae and pins were imported into three-dimensional (3D) modelling software and the fractures were virtually reduced. A multi-component 3D printed alignment jig was created that encompassed the pins in their aligned configuration. Orthogonal radiographs were taken after alignment jig application. Intact and post-alignment tibial lengths and joint angles were compared. Rotational alignment was subjectively evaluated. Results Post-alignment tibial lengths differed on the mediolateral and craniocaudal radiographs by an average of 1.55 and 1.43% respectively. Post-alignment mechanical medial proximal tibial angle, mechanical medial distal tibial angle and mechanical caudal proximal tibial angle had an average difference of 1.67°, 1.92° and 2.17° respectively. Differences in tibial length and joint angles were not significant (p > 0.05). Clinical Significance While in vivo evaluation is necessary, this technique to align diaphyseal fractures percutaneously using computer modelling and 3D printing is technically feasible and may facilitate the clinical use of minimally invasive osteosynthesis techniques.

scholarly journals Morphological and functional properties of the conducting human airways investigated by in vivo computed tomography and in vitro MRI

2018 ◽  
Vol 124 (2) ◽  
pp. 400-413 ◽  
Author(s):  
Tristan Van de Moortele ◽  
Christine H. Wendt ◽  
Filippo Coletti
Keyword(s):  
Computed Tomography ◽  
Structure Function ◽  
Transverse Velocity ◽  
Three Dimensional ◽  
Diameter Ratio ◽  
Secondary Flows ◽  
Axial Component ◽  
Branch Diameter ◽  
Seven Generations

The accurate representation of the human airway anatomy is crucial for understanding and modeling the structure-function relationship in both healthy and diseased lungs. The present knowledge in this area is based on morphometric studies of excised lung casts, partially complemented by in vivo studies in which computed tomography (CT) was used on a small number of subjects. In the present study, we analyzed CT scans of a cohort of healthy subjects and obtained comprehensive morphometric information down to the seventh generation of bronchial branching, including airway diameter, length, branching angle, and rotation angle. Although some of the geometric parameters (such as the child-to-parent branch diameter ratio) are found to be in line with accepted values, for others (such as the branch length-to-diameter ratio) our findings challenge the common assumptions. We also evaluated several metrics of self-similarity, including the fractal dimension of the airway tree. Additionally, we used phase-contrast magnetic resonance imaging (MRI) to obtain the volumetric flow field in the three-dimensional-printed airway model of one of the subjects during steady inhalation. This is used to relate structural and functional parameters and, in particular, to close the power-law relationship between branch flow rate and diameter. The diameter exponent is found to be significantly lower than in the usually assumed Poiseuille regime, which we attribute to the strong secondary (i.e., transverse) velocity component. The strength of the secondary velocity with respect to the axial component exceeds the levels found in idealized airway models and persists within the first seven generations. NEW & NOTEWORTHY We performed a comprehensive computed tomography-based study of the conductive airway morphology in normal human subjects, including branch diameter, length, and mutual angles. We found significant departure from classic homothetic relationships. We also carried out MRI measurements of the three-dimensional inspiratory flow in an anatomy-based model and directly assessed structure-function relationships that have so far been assumed. We found that strong secondary flows (i.e., transverse velocity components) persist through the first seven generations of bronchial branching.

Reproducibility of bone micro-architecture measurements in rodents by in vivo micro-computed tomography is maximized with three-dimensional image registration

Bone ◽  
2010 ◽  
Vol 46 (1) ◽  
pp. 155-161 ◽  
Author(s):  
Kyle K. Nishiyama ◽  
Graeme M. Campbell ◽  
Robert J. Klinck ◽  
Steven K. Boyd
Keyword(s):  
Computed Tomography ◽  
Image Registration ◽  
Three Dimensional ◽  
Micro Computed Tomography ◽  
Dimensional Image

scholarly journals Hibrid képalkotás: klinikai evidenciák, lehetőségek

2015 ◽  
Vol 156 (52) ◽  
pp. 2110-2115
Author(s):  
György Trencsényi ◽  
Sándor Kristóf Barna ◽  
Ildikó Garai
Keyword(s):  
Computed Tomography ◽  
Hybrid Imaging ◽  
Single Photon ◽  
Photon Emission ◽  
Research Process ◽  
Clinical Diagnostics ◽  
The Body ◽  
Drug Candidate ◽  
Emission Computed Tomography

Nowadays the hybrid imaging technologies which combine the modern equipments of radiology and nuclear medicine play an important role in both the translational research process and clinical diagnostics. Among the routine diagnostic imaging procedures positron emission tomography and single photon emission computed tomography combined with computed tomography or magnetic resonance imaging currently belong to the most advanced techniques allowing that functional and morphological images can be superimposed on each other in the same position. The hybrid imaging equipments provide useful information about the pathological processes in the body due to their high sensibility and resolution. Furthermore, with the help of these imaging modalities we can get acquainted with the biochemical and pathobiochemical processes that are essential for understanding and treating diseases, or getting acquainted with the behaviour of a new drug candidate. With the help of the clinical and preclinical non-invasive in vivo molecular imaging systems the drug developing process can be shortened and its costs can be reduced. Orv. Hetil., 2015, 156(52), 2110–2115.

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