Activatable Multifunctional Persistent Luminescence Nanoparticle/Copper Sulfide Nanoprobe for in Vivo Luminescence Imaging-Guided Photothermal Therapy

Construction of persistent luminescence nanophosphor-copper sulfide hybrid FRET nanoprobes for background-free bioimaging-guided investigation of food-borne aflatoxin in vivo.

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Chromium-Doped Zinc Gallogermanate@Zeolitic Imidazolate Framework-8: A Multifunctional Nanoplatform for Rechargeable In Vivo Persistent Luminescence Imaging and pH-Responsive Drug Release

ACS Applied Materials & Interfaces ◽

10.1021/acsami.8b19172 ◽

2018 ◽

Vol 11 (2) ◽

pp. 1907-1916 ◽

Cited By ~ 22

Author(s):

Ying Lv ◽

Dandan Ding ◽

Yixi Zhuang ◽

Yushuo Feng ◽

Junpeng Shi ◽

...

Keyword(s):

Drug Release ◽

Persistent Luminescence ◽

Ph Responsive ◽

Zeolitic Imidazolate Framework ◽

Luminescence Imaging

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Near-infrared persistent luminescence phosphors ZnGa2O4:Cr3+ as an accurately tracker to photothermal therapy in vivo for visual treatment

Materials Science and Engineering C ◽

10.1016/j.msec.2017.05.053 ◽

2017 ◽

Vol 79 ◽

pp. 372-381 ◽

Cited By ~ 8

Author(s):

Hongbin Chen ◽

Bin Zheng ◽

Chao Liang ◽

Li Zhao ◽

Ying Zhang ◽

...

Keyword(s):

Photothermal Therapy ◽

Near Infrared ◽

Persistent Luminescence

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Fe-doped copper sulfide nanoparticles for in vivo magnetic resonance imaging and simultaneous photothermal therapy

Nanotechnology ◽

10.1088/1361-6528/ab2c13 ◽

2019 ◽

Vol 30 (41) ◽

pp. 415101 ◽

Cited By ~ 3

Author(s):

Lei Wang ◽

Xiaofei Xu ◽

Xingguo Mu ◽

Qinghe Han ◽

Jianhua Liu ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Copper Sulfide ◽

Photothermal Therapy ◽

Resonance Imaging

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Glutathione-capped, renal-clearable CuS nanodots for photoacoustic imaging and photothermal therapy

Journal of Materials Chemistry B ◽

10.1039/c7tb01517h ◽

2017 ◽

Vol 5 (31) ◽

pp. 6366-6375 ◽

Cited By ~ 19

Author(s):

Guohai Liang ◽

Xudong Jin ◽

Huan Qin ◽

Da Xing

Keyword(s):

Renal Clearance ◽

Copper Sulfide ◽

Photothermal Therapy ◽

Photoacoustic Imaging

Glutathione-capped copper sulfide nanodots with efficient renal clearance show promise for in vivo photoacoustic imaging and photothermal therapy.

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Thermosensitive drug-loading system based on copper sulfide nanoparticles for combined photothermal therapy and chemotherapy in vivo

Biomaterials Science ◽

10.1039/c8bm00799c ◽

2018 ◽

Vol 6 (12) ◽

pp. 3219-3230 ◽

Cited By ~ 9

Author(s):

Zhenwei Yuan ◽

Sisi Qu ◽

Yuanyuan He ◽

Yue Xu ◽

Li Liang ◽

...

Keyword(s):

Phase Change ◽

Phase Change Material ◽

Copper Sulfide ◽

Photothermal Therapy ◽

Drug Loading ◽

Physiological Conditions ◽

Loading System ◽

Change Material

A phase-change material was used to design CuS-DOX-MBA@PCM nanoparticles, which could release the drug quickly in physiological conditions.

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Persistent luminescence nanoparticles for cancer theranostics application

Journal of Nanobiotechnology ◽

10.1186/s12951-021-00862-z ◽

2021 ◽

Vol 19 (1) ◽

Author(s):

Nian Liu ◽

Xiao Chen ◽

Xia Sun ◽

Xiaolian Sun ◽

Junpeng Shi

Keyword(s):

Uv Light ◽

Combined Therapy ◽

Tumor Therapy ◽

High Sensitivity ◽

Persistent Luminescence ◽

Therapeutic Drugs ◽

High Penetration ◽

Recent Developments ◽

Cancer Theranostics

AbstractPersistent luminescence nanoparticles (PLNPs) are unique optical materials that emit afterglow luminescence after ceasing excitation. They exhibit unexpected advantages for in vivo optical imaging of tumors, such as autofluorescence-free, high sensitivity, high penetration depth, and multiple excitation sources (UV light, LED, NIR laser, X-ray, and radiopharmaceuticals). Besides, by incorporating other functional molecules, such as photosensitizers, photothermal agents, or therapeutic drugs, PLNPs are also widely used in persistent luminescence (PersL) imaging-guided tumor therapy. In this review, we first summarize the recent developments in the synthesis and surface functionalization of PLNPs, as well as their toxicity studies. We then discuss the in vivo PersL imaging and multimodal imaging from different excitation sources. Furthermore, we highlight PLNPs-based cancer theranostics applications, such as fluorescence-guided surgery, photothermal therapy, photodynamic therapy, drug/gene delivery and combined therapy. Finally, future prospects and challenges of PLNPs in the research of translational medicine are also discussed.

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