First Aldol Cross-Linked Hyaluronic Acid Hydrogel: Fast and Hydrolytically Stable Hydrogel with Tissue Adhesive Properties

2019 ◽  
Vol 11 (41) ◽  
pp. 38232-38239 ◽  
Author(s):  
Daniel Bermejo-Velasco ◽  
Sandeep Kadekar ◽  
Marcus Vinicius Tavares da Costa ◽  
Oommen P. Oommen ◽  
Kristofer Gamstedt ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Tissue Adhesive ◽  
Adhesive Properties ◽  
Hyaluronic Acid Hydrogel

Interpenetrating Gallol Functionalized Tissue Adhesive Hyaluronic Acid Hydrogel Polarizes Macrophages to an Immunosuppressive Phenotype

2021 ◽  
Author(s):  
Sumanta Samanta ◽  
Vignesh Kumar Rangasami ◽  
Heela Sarlus ◽  
Jay R.K. Samal ◽  
Austin D. Evans ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Tissue Adhesive ◽  
Hyaluronic Acid Hydrogel

Tissue Adhesive Catechol-Modified Hyaluronic Acid Hydrogel for Effective, Minimally Invasive Cell Therapy

2015 ◽  
Vol 25 (25) ◽  
pp. 3814-3824 ◽  
Author(s):  
Jisoo Shin ◽  
Jung Seung Lee ◽  
Changhyun Lee ◽  
Hyun-Ji Park ◽  
Kisuk Yang ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Cell Therapy ◽  
Minimally Invasive ◽  
Tissue Adhesive ◽  
Hyaluronic Acid Hydrogel ◽  
Invasive Cell

Synergistic regenerative effects of functionalized endometrial stromal cells with hyaluronic acid hydrogel in a murine model of uterine damage

2019 ◽  
Vol 89 ◽  
pp. 139-151 ◽  
Author(s):  
Yoon Young Kim ◽  
Kyu-Hyung Park ◽  
Yong Jin Kim ◽  
Moon Suk Kim ◽  
Hung Ching Liu ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Murine Model ◽  
Stromal Cells ◽  
Endometrial Stromal Cells ◽  
Hyaluronic Acid Hydrogel

scholarly journals Investigation of Changes in Saliva in Radiotherapy-Induced Head Neck Cancer Patients

2021 ◽  
Vol 18 (4) ◽  
pp. 1629
Author(s):  
Christina Winter ◽  
Roman Keimel ◽  
Markus Gugatschka ◽  
Dagmar Kolb ◽  
Gerd Leitinger ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Salivary Glands ◽  
Treatment Options ◽  
Chemical Properties ◽  
Head Neck Cancer ◽  
Potential Candidate ◽  
Adhesive Properties ◽  
Whole Saliva ◽  
Radiation Induced ◽  
Unstimulated Whole Saliva

The intact function of the salivary glands is of utmost importance for oral health. During radiotherapy in patients with head and neck tumors, the salivary glands can be damaged, causing the composition of saliva to change. This leads to xerostomia, which is a primary contributor to oral mucositis. Medications used for protective or palliative treatment often show poor efficacy as radiation-induced changes in the physico-chemical properties of saliva are not well understood. To improve treatment options, this study aimed to carefully examine unstimulated whole saliva of patients receiving radiation therapy and compare it with healthy unstimulated whole saliva. To this end, the pH, osmolality, electrical conductivity, buffer capacity, the whole protein and mucin concentrations, and the viscoelastic and adhesive properties were investigated. Moreover, hyaluronic acid was examined as a potential candidate for a saliva replacement fluid. The results showed that the pH of radiation-induced saliva shifted from neutral to acidic, the osmolality increased and the viscoelastic properties changed due to a disruption of the mucin network and a change in water secretion from the salivary glands. By adopting an aqueous 0.25% hyaluronic acid formulation regarding the lost properties, similar adhesion characteristics as in healthy, unstimulated saliva could be achieved.

An in vitro hyaluronic acid hydrogel based platform to model dormancy in brain metastatic breast cancer cells

2020 ◽  
Vol 107 ◽  
pp. 65-77 ◽  
Author(s):  
Akshay A. Narkhede ◽  
James H. Crenshaw ◽  
David K. Crossman ◽  
Lalita A. Shevde ◽  
Shreyas S. Rao
Keyword(s):  
Breast Cancer ◽  
Hyaluronic Acid ◽  
Metastatic Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Metastatic Breast ◽  
Hyaluronic Acid Hydrogel

Morphological and morphometric analyses of crushed sciatic nerves after application of a purified protein from natural latex and hyaluronic acid hydrogel

2014 ◽  
Vol 32 (5) ◽  
pp. 164-170 ◽  
Author(s):  
Vanessa Cristina Pereira Barreiros ◽  
Fernando José Dias ◽  
Mamie Mizusaki Iyomasa ◽  
Joaquim Coutinho-Netto ◽  
Luiz Gustavo de Sousa ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Morphometric Analyses ◽  
Sciatic Nerves ◽  
Hyaluronic Acid Hydrogel
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