Immunoassay for Cardiac Troponin I with Fluorescent Signal Amplification by Hydrolyzed Coumarin Released from a Metal–Organic Framework

2019 ◽  
Vol 2 (11) ◽  
pp. 7170-7177 ◽  
Author(s):  
Xujie Wang ◽  
Xiaoying Wang ◽  
Ying Han ◽  
He Li ◽  
Qing Kang ◽  
...  
Keyword(s):  
Cardiac Troponin ◽  
Signal Amplification ◽  
Troponin I ◽  
Metal Organic Framework ◽  
Cardiac Troponin I ◽  
Fluorescent Signal ◽  
Metal Organic ◽  
Organic Framework

scholarly journals A novel, fast, high sensitivity biosensor for supporting therapeutic decisions and onset actions for chest pain cases

RSC Advances ◽  
2019 ◽  
Vol 9 (35) ◽  
pp. 20463-20471 ◽  
Author(s):  
Sheta M. Sheta ◽  
Said M. El-Sheikh ◽  
Mokhles M. Abd-Elzaher ◽  
Mosaad L. Ghanem ◽  
Salem R. Salem
Keyword(s):  
Myocardial Infarction ◽  
Chest Pain ◽  
Cardiac Troponin ◽  
Troponin I ◽  
Metal Organic Framework ◽  
High Sensitivity ◽  
Cardiac Troponin I ◽  
Therapeutic Decisions ◽  
Metal Organic ◽  
Organic Framework

A novel organic nano linker (NL) and manganese metal–organic framework (Mn–MOF) were synthesized and fully characterized. A promising cardiac troponin-I potentiometric biosensor based on Mn–MOF could be used for early myocardial infarction diagnosis.

scholarly journals Sensitive impedimetric detection of troponin I with metal–organic framework composite electrode

RSC Advances ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 2167-2174
Author(s):  
Arushi Gupta ◽  
Sandeep Kumar Sharma ◽  
Vivek Pachauri ◽  
Sven Ingebrandt ◽  
Suman Singh ◽  
...  
Keyword(s):  
Cardiac Troponin ◽  
Composite Electrode ◽  
Troponin I ◽  
Limit Of Detection ◽  
Metal Organic Framework ◽  
Cardiac Troponin I ◽  
Sensitive Detection ◽  
Wide Concentration Range ◽  
Screen Printed Electrode ◽  
Metal Organic

A Cu-MOF/PANI modified screen-printed electrode based immunosensing technique is described for the sensitive detection of cardiac troponin I. The sensor provides detection over a wide concentration range with a limit of detection of 0.8 ng mL−1.

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