Biomimetic Glycoside Hydrolysis by a Microgel Templated with a Competitive Glycosidase Inhibitor

ACS Catalysis ◽  
2018 ◽  
Vol 8 (9) ◽  
pp. 8788-8795 ◽  
Author(s):  
Babloo Sharma ◽  
Jessica B. Pickens ◽  
Susanne Striegler ◽  
James D. Barnett
Keyword(s):  
Glycosidase Inhibitor ◽  
Glycoside Hydrolysis

Design and synthesis of glycosidase inhibitor 5-amino-1,2,3,4-cyclohexanetetrol derivatives from (−)-vibo-quercitol

2005 ◽  
Vol 13 (13) ◽  
pp. 4306-4314 ◽  
Author(s):  
Seiichiro Ogawa ◽  
Miwako Asada ◽  
Yoriko Ooki ◽  
Midori Mori ◽  
Masayoshi Itoh ◽  
...  
Keyword(s):  
Design And Synthesis ◽  
Glycosidase Inhibitor

Four Orders of Magnitude Rate Increase in Artificial Enzyme-Catalyzed Aryl Glycoside Hydrolysis

2005 ◽  
Vol 70 (18) ◽  
pp. 7217-7226 ◽  
Author(s):  
Fernando Ortega-Caballero ◽  
Jeannette Bjerre ◽  
Line Skall Laustsen ◽  
Mikael Bols
Keyword(s):  
Rate Increase ◽  
Artificial Enzyme ◽  
Glycoside Hydrolysis ◽  
Aryl Glycoside

7-Deoxy-6-epi-castanospermine, a Trihydroxyindolizidine Alkaloid Glycosidase Inhibitor from Castanospermum australe

1990 ◽  
Vol 53 (3) ◽  
pp. 609-614 ◽  
Author(s):  
Russell J. Molyneux ◽  
Joseph E. Tropea ◽  
Alan D. Elbein
Keyword(s):  
Glycosidase Inhibitor ◽  
Castanospermum Australe

STRUCTURE OF THE EXTRACELLULAR POLYSACCHARIDE PRODUCED BY XANTHOMONAS ORYZAE

1962 ◽  
Vol 40 (12) ◽  
pp. 2204-2213 ◽  
Author(s):  
A. Misaki ◽  
S. Kirkwood ◽  
J. V. Scaletti ◽  
F. Smith
Keyword(s):  
Acid Hydrolysis ◽  
Glucuronic Acid ◽  
Periodate Oxidation ◽  
Extracellular Polysaccharide ◽  
Xanthomonas Oryzae ◽  
Sodium Borohydride Reduction ◽  
Glycoside Hydrolysis ◽  
Hydrolysis Of ◽  
Structural Significance ◽  
Molecular Proportion

The extracellular polysaccharide isolated from cultures of Xanthomonas oryzae is composed of D-glucose (5 molecular proportions), D-glucuronic acid (2 molecular proportions), and D-mannose (5 molecular proportions). Acid hydrolysis of this polysaccharide, which contains 0.3% combined pyruvic acid, yields 2-O-β-D-glucopyranosyluronic acid D-mannose, which has been characterized as its crystalline fully methylated β-glycoside. Hydrolysis of the methylated polysaccharide gives 2,3,4,6-tetra-O-methyl-D-mannose (3 molecular proportions), 2,3,4-tri-O-methyl-D-glucuronic acid (1 molecular proportion), 2,3,6-tri-O-methyl-D-glucose (4 molecular proportions), 3,4,6-tri-O-methyl-D-mannose (2 molecular proportions), 2,6-di-O-methyl-D-glucose (3 molecular proportions), 2,3-di-O-methyl-D-glucose (1 molecular proportion). The polyalcohol derived from the polysaccharide by periodate oxidation followed by sodium borohydride reduction gives upon acid hydrolysis glycerol (2 molecular proportions), erythritol (1 molecular proportion), and D-glucose (1 molecular proportion). The general structural significance of these findings is discussed.

Remarkable Supramolecular Catalysis of Glycoside Hydrolysis by a Cyclodextrin Cyanohydrin

2005 ◽  
Vol 127 (10) ◽  
pp. 3238-3239 ◽  
Author(s):  
Fernando Ortega-Caballero ◽  
Cyril Rousseau ◽  
Brian Christensen ◽  
Torben Ellebæk Petersen ◽  
Mikael Bols
Keyword(s):  
Supramolecular Catalysis ◽  
Glycoside Hydrolysis

Synthesis of Selenium Analogues of the Naturally Occurring Glycosidase Inhibitor Salacinol and Their Evaluation as Glycosidase Inhibitors†

2002 ◽  
Vol 124 (28) ◽  
pp. 8245-8250 ◽  
Author(s):  
Blair D. Johnston ◽  
Ahmad Ghavami ◽  
Morten T. Jensen ◽  
Birte Svensson ◽  
B. Mario Pinto
Keyword(s):  
Glycosidase Inhibitors ◽  
Naturally Occurring ◽  
Glycosidase Inhibitor

Conformational flexibility of sulphur linked saccharides a possible key to their glycosidase inhibitor activity

2008 ◽  
Vol 34 (4) ◽  
pp. 391-402 ◽  
Author(s):  
Gerhard A. Venter ◽  
Richard P. Matthews ◽  
Kevin J. Naidoo
Keyword(s):  
Conformational Flexibility ◽  
Inhibitor Activity ◽  
Glycosidase Inhibitor

A stereoselective transformation of (−)-shikimic acid into (3R,4S,5R,7R)-7-(hydroxymethyl)azepane-3,4,5-triol, a potential glycosidase inhibitor

2015 ◽  
Vol 26 (5-6) ◽  
pp. 320-323 ◽  
Author(s):  
Marcos A. González-Castro ◽  
Darren L. Poole ◽  
Juan C. Estévez ◽  
George W.J. Fleet ◽  
Ramón J. Estévez
Keyword(s):  
Shikimic Acid ◽  
Glycosidase Inhibitor
Sign in / Sign up

Export Citation Format

Share Document