Cancer Cell Membrane-Biomimetic Nanoprobes with Two-Photon Excitation and Near-Infrared Emission for Intravital Tumor Fluorescence Imaging

ACS Nano ◽  
2018 ◽  
Vol 12 (2) ◽  
pp. 1350-1358 ◽  
Author(s):  
Yanlin Lv ◽  
Ming Liu ◽  
Yong Zhang ◽  
Xuefei Wang ◽  
Fan Zhang ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Fluorescence Imaging ◽  
Cancer Cell ◽  
Near Infrared ◽  
Infrared Emission ◽  
Two Photon ◽  
Photon Excitation ◽  
Near Infrared Emission ◽  
Two Photon Excitation

AIEgen Nanoparticles of Arylamino Fumaronitrile Derivative with High Near-Infrared Emission for Two-Photon Imaging and in Vivo Cell Tracking

2018 ◽  
Vol 2 (1) ◽  
pp. 430-436 ◽  
Author(s):  
Zhonghua Liu ◽  
Fang Liu ◽  
Yijian Gao ◽  
Weixia Qing ◽  
Yongwei Huang ◽  
...  
Keyword(s):  
Cell Tracking ◽  
Near Infrared ◽  
Infrared Emission ◽  
Two Photon ◽  
Photon Imaging ◽  
Two Photon Imaging ◽  
Near Infrared Emission

scholarly journals Two-Photon–NIR-II Antimicrobial Graphene-Nanoagent for Ultraviolet–NIR Imaging and Photoinactivation

2021 ◽  
Author(s):  
WEN-SHUO KUO ◽  
Chia-Yuan Chang ◽  
Ping-Ching Wu ◽  
Jiu-Yao Wang
Keyword(s):  
Photodynamic Therapy ◽  
Quantum Yield ◽  
Chemical Modification ◽  
Near Infrared ◽  
Photon Absorption ◽  
Excitation Wavelength ◽  
Strong Electron ◽  
Two Photon ◽  
Photon Excitation ◽  
Two Photon Excitation

Abstract BackgroundNitrogen doping and amino-group functionalization, which result in strong electron donation, can be achieved through chemical modification. Large π-conjugated systems of graphene quantum dot (GQD)-based materials acting as electron donors can be chemically manipulated with low two-photon excitation energy in a short photoexcitation time for improving the charge transfer efficiency of sorted nitrogen-doped amino acid–functionalized GQDs (sorted amino-N-GQDs). ResultsIn this study, a self-developed femtosecond Ti-sapphire laser optical system (222.7 nJ pixel−1 with 100-170 scans, approximately 0.65-1.11 s of total effective exposure times; excitation wavelength: 960 nm in the near-infrared II region) was used for chemical modification. The sorted amino-N-GQDs exhibited enhanced two-photon absorption, post-two-photon excitation stability, two-photon excitation cross-section, and two-photon luminescence through the radiative pathway. The lifetime and quantum yield of the sorted amino-N-GQDs decreased and increased, respectively. Furthermore, the sorted amino-N-GQDs exhibited excitation-wavelength-independent photoluminescence in the near-infrared region and generated reactive oxygen species after two-photon excitation. An increase in the size of the sorted amino-N-GQDs boosted photochemical and electrochemical efficacy and resulted in high photoluminescence quantum yield and highly efficient two-photon photodynamic therapy. ConclusionThe sorted dots can be used in two-photon contrast probes for tracking and localizing analytes during two-photon imaging in a biological environment and for conducting two-photon photodynamic therapy for eliminating infectious microbes.

scholarly journals Two-photon excited deep-red and near-infrared emissive organic co-crystals

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Yu Wang ◽  
Huang Wu ◽  
Penghao Li ◽  
Su Chen ◽  
Leighton O. Jones ◽  
...  
Keyword(s):  
Cross Sections ◽  
Optical Materials ◽  
Near Infrared ◽  
Infrared Emission ◽  
Photon Absorption ◽  
Electromagnetic Spectrum ◽  
Absorption Bands ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Near Infrared Emission

Abstract Two-photon excited near-infrared fluorescence materials have garnered considerable attention because of their superior optical penetration, higher spatial resolution, and lower optical scattering compared with other optical materials. Herein, a convenient and efficient supramolecular approach is used to synthesize a two-photon excited near-infrared emissive co-crystalline material. A naphthalenediimide-based triangular macrocycle and coronene form selectively two co-crystals. The triangle-shaped co-crystal emits deep-red fluorescence, while the quadrangle-shaped co-crystal displays deep-red and near-infrared emission centered on 668 nm, which represents a 162 nm red-shift compared with its precursors. Benefiting from intermolecular charge transfer interactions, the two co-crystals possess higher calculated two-photon absorption cross-sections than those of their individual constituents. Their two-photon absorption bands reach into the NIR-II region of the electromagnetic spectrum. The quadrangle-shaped co-crystal constitutes a unique material that exhibits two-photon absorption and near-infrared emission simultaneously. This co-crystallization strategy holds considerable promise for the future design and synthesis of more advanced optical materials.

scholarly journals Cover Feature: A Three‐Color Fluorescent Supramolecular Nanoassembly of Phototherapeutics Activable by Two‐Photon Excitation with Near‐Infrared Light (Chem. Eur. J. 29/2019)

2019 ◽  
Vol 25 (29) ◽  
pp. 7041-7041
Author(s):  
Aurore Fraix ◽  
Vladimir Kirejev ◽  
Milo Malanga ◽  
Éva Fenyvesi ◽  
Szabolcs Béni ◽  
...  
Keyword(s):  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Two Photon ◽  
Photon Excitation ◽  
Two Photon Excitation

Lysosome-targetable polythiophene nanoparticles for two-photon excitation photodynamic therapy and deep tissue imaging

2017 ◽  
Vol 5 (20) ◽  
pp. 3651-3657 ◽  
Author(s):  
Shaojing Zhao ◽  
Guangle Niu ◽  
Feng Wu ◽  
Li Yan ◽  
Hongyan Zhang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Quantum Yield ◽  
Fluorescence Imaging ◽  
Cross Section ◽  
Tissue Imaging ◽  
Deep Tissue ◽  
Two Photon ◽  
Photon Excitation ◽  
Deep Tissue Imaging ◽  
Two Photon Excitation

Polythiophene nanoparticles with large TPA cross section and high1O2generation quantum yield have been developed for simultaneous lysosome-targetable fluorescence imaging and photodynamic therapy.

Sign in / Sign up

Export Citation Format

Share Document