scholarly journals Comprehensive Analysis of Low Molecular Weight Serum Proteome Enrichment for Mass Spectrometric Studies

ACS Omega ◽  
2020 ◽  
Vol 5 (44) ◽  
pp. 28877-28888
Author(s):  
Lipi Das ◽  
Vedang Murthy ◽  
Ashok K. Varma

2016 ◽  
Vol 8 (26) ◽  
pp. 5190-5196 ◽  
Author(s):  
J. Yang ◽  
J. Zhu ◽  
R. Pei ◽  
J. A. Oliver ◽  
D. W. Landry ◽  
...  

We present a microfluidic aptamer-based biosensor for detection of low-molecular-weight biomarkers in patient samples.



2004 ◽  
Vol 25 (9) ◽  
pp. 1299-1306 ◽  
Author(s):  
Robert G. Harper ◽  
Sarah R. Workman ◽  
Shayne Schuetzner ◽  
Aaron T. Timperman ◽  
Jennifer N. Sutton


1975 ◽  
Vol 21 (9) ◽  
pp. 1294-1296 ◽  
Author(s):  
Hartmut M Liebich ◽  
Ossama Al-Babbili ◽  
Albert Zlatkis ◽  
Kyoung Kim

Abstract We studied the aliphatic alcohols in 100 urines from 25 patients with diabetes mellitus under treatment with insulin, oral antidiabetic medication, or special diet. The procedure involves adsorption of the low-molecular-weight urinary metabolites on a porous polymer of 2,6-diphenyl-p-phenylene oxide (Tenax GC), gas-chromatographic separation, mass spectrometric identification, and mass fragmentographic representation of the primary alcohols by a computer. The concentrations of ethanol, n-propanol, isobutanol, n-butanol, and isopentanol are increased as compared with urine from normal persons.



2020 ◽  
Vol 35 (11) ◽  
pp. 2475-2478
Author(s):  
Tyler J. Williams ◽  
Jacob R. Bills ◽  
R. Kenneth Marcus

The versatility of the LS-APGD microplasma is extended beyond elemental and polar molecular species to non-polar, low molecular weight polyaromatic hydrocarbons. Insights into ionization mechanisms are gained, with preliminary LODs determined.



PROTEOMICS ◽  
2009 ◽  
Vol 9 (3) ◽  
pp. 625-635 ◽  
Author(s):  
Matthias Plöscher ◽  
Bernhard Granvogl ◽  
Mikael Zoryan ◽  
Veronika Reisinger ◽  
Lutz Andreas Eichacker


2003 ◽  
Vol 1 (3-4) ◽  
pp. 285-298 ◽  
Author(s):  
Elena Gaggelli ◽  
Nicola D'Amelio ◽  
Nicola Gaggelli ◽  
Gianni Valensin ◽  
Lucia Bovalini ◽  
...  

A low-molecular weight chromium-containing fraction of the material resulting from dichromate reduction by bovine liver homogenate was investigated by NMR and ES-MS. The ES-MS spectrum showed a readily detectable peak at m/z = 786.1. The same molecular weight reasonably agreed with the relatively low diffusion coefficient measured by NMR-DOSY experiments on the main species observed in the1H NMR spectrum. At least two downfield shifted and broad paramagnetic signals were apparent in the1H NMR spectrum. Temperature dependence of chemical shift was exploited in order to estimate the diamagnetic shift of the signals in the diamagnetic region of the spectrum. 2D TOCSY, NOESY, COSY and1H-3C HMQC spectra revealed the presence of aromatic protons (which were assigned as His residues), Gly and some other short chain amino-acids. Combinations of the molecular masses of such components together with acetate (which is present in the solution) and chromium atoms allowed a tentative proposal of a model for the compound.



2012 ◽  
Vol 405 (2-3) ◽  
pp. 1047-1065 ◽  
Author(s):  
I. Bonaduce ◽  
M. P. Colombini ◽  
I. Degano ◽  
F. Di Girolamo ◽  
J. La Nasa ◽  
...  






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