Proton magnetic resonance of NADH in water-methanol mixtures. Conformational change and behavior of exchangeable proton resonances as a function of temperature

1980 ◽  
Vol 102 (2) ◽  
pp. 534-538 ◽  
Author(s):  
James Tropp ◽  
Alfred G. Redfield
Keyword(s):  
Magnetic Resonance ◽  
Conformational Change ◽  
Proton Magnetic Resonance ◽  
Exchangeable Proton ◽  
Proton Resonances ◽  
And Behavior

Proton Magnetic Resonance Spectroscopic Method for Determination of Phenylbutazone and Oxyphenbutazone in Tablets

1988 ◽  
Vol 71 (3) ◽  
pp. 525-527
Author(s):  
Sajid Husain ◽  
M Kifayatullah ◽  
R NAGESWARA RAO
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Proton Magnetic Resonance ◽  
Spectroscopic Method ◽  
Internal Standard ◽  
Aromatic Proton ◽  
British Pharmacopoeia ◽  
Standard Deviations ◽  
Proton Resonances

Abstract A simple, specific, and rapid 'H nuclear magnetic resonance spectroscopic method for the assay of phenylbutazone and oxyphenbutazone is described. Spectra are recorded in CDC13 containing 1,3- dichloro-5-nitrobenzene as an internal standard. The aromatic proton resonances for the standard, at 57.7 and 8.2, are well separated from those of phenylbutazone and oxyphenbutazone, which are in the region of 56.5-7.3 ppm. Average percent recoveries of phenylbutazone and oxyphenbutazone were 98.9 and 98.6 with standard deviations of 0.6 and 0.7, respectively. Commercial formulations were analyzed and the results obtained by the proposed method closely agreed with those found by the British Pharmacopoeia method

A high-field proton magnetic resonance and nuclear Overhauser effect study of prostaglandin E2

1980 ◽  
Vol 58 (15) ◽  
pp. 1577-1583 ◽  
Author(s):  
George Kotovych ◽  
Gerdy H. M. Aarts ◽  
Glen Bigam
Keyword(s):  
Magnetic Resonance ◽  
Proton Magnetic Resonance ◽  
Nuclear Overhauser Effect ◽  
Double Resonance ◽  
Effect Study ◽  
Prostaglandin E ◽  
Hindered Rotation ◽  
H Nmr ◽  
Proton Resonances ◽  
Nuclear Overhauser

The proton magnetic resonance (1H nmr) spectrum of prostaglandin E2 (PGE2) in CDCl3 at 400 MHz bas been completely analyzed utilizing homonuclear double resonance, inversion recovery, and nOe difference experiments. The nOe difference experiments are used to assign points of configuration, namely the H-10β and the H-10α proton resonances. A spectral analysis shows that the two protons at C-3 and the two protons at C-4 are nonequivalent, indicating a hindered rotation of the chain. This is possibly due to the hairpin conformation of PGE2 in solution.

pH-Induced Conformational Change of ATPase Inhibitor from Yeast Mitochondria. A Proton Magnetic Resonance Study

1983 ◽  
Vol 93 (1) ◽  
pp. 189-196 ◽  
Author(s):  
Shigeru FUJII ◽  
Tadao HASHIMOTO ◽  
Yukuo YOSHIDA ◽  
Retsu MIURA ◽  
Toshio YAMANO ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Conformational Change ◽  
Proton Magnetic Resonance ◽  
Yeast Mitochondria ◽  
Magnetic Resonance Study ◽  
Atpase Inhibitor ◽  
Proton Magnetic Resonance Study

Assignment of the non-exchangeable proton resonances of d(C-G-C-G-A-A-T-T-C-G-C-G) using two-dimensional nuclear magnetic resonance methods

1983 ◽  
Vol 171 (3) ◽  
pp. 319-336 ◽  
Author(s):  
Dennis R. Hare ◽  
David E. Wemmer ◽  
Shan-Ho Chou ◽  
Gary Drobny ◽  
Brian R. Reid
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Two Dimensional ◽  
Exchangeable Proton ◽  
Proton Resonances ◽  
Nuclear Magnetic

A nuclear Overhauser effect difference study and a two-dimensional J proton magnetic resonance study of (6S)-prostaglandin I1

1981 ◽  
Vol 59 (10) ◽  
pp. 1449-1454 ◽  
Author(s):  
George Kotovych ◽  
Gerdy H. M. Aarts ◽  
Tom T. Nakashima
Keyword(s):  
Magnetic Resonance ◽  
Proton Magnetic Resonance ◽  
Nuclear Overhauser Effect ◽  
Chemical Shifts ◽  
Coupling Constants ◽  
Two Dimensional ◽  
Overhauser Effect ◽  
Effect Difference ◽  
Proton Resonances ◽  
Nuclear Overhauser

High-field nuclear Overhauser effect difference measurements allowed the assignment of the proton resonances for (6S)-prostaglandin I1 in phosphate buffer solutions. The two-dimensional J proton magnetic resonance experiments complemented these studies, as they also allowed the structure of several multiplets to be obtained when these multiplets are hidden by nearby resonances in a normal spectrum. The chemical shifts and coupling constants are compared with the data obtained previously for (6R)-prostaglandin I1.

Hydroxyl proton resonances of methyl 4,6-O-benzyIidene-α- and β-D-glucopyranosides and their derivatives in dimethyl sulfoxide solution

1977 ◽  
Vol 55 (1) ◽  
pp. 141-144 ◽  
Author(s):  
Yôtaro Kondo ◽  
Keisuke Kitamura
Keyword(s):  
Magnetic Resonance ◽  
Dimethyl Sulfoxide ◽  
Proton Magnetic Resonance ◽  
Coupling Constants ◽  
Hydroxyl Group ◽  
Hydroxyl Proton ◽  
Dimethyl Sulfoxide Solution ◽  
Vicinal Diols ◽  
Proton Resonances ◽  
Derivatives Of

Proton magnetic resonance spectra of methyl 4,6-O-benzylidene-α- and β-D-glucopyranosides (1 and 10) and their mono-substituted derivatives are determined in dimethyl sulfoxide solution. Assignments of the hydroxyl group resonances of 1 and 10 are confirmed by means of INDOR techniques. It is shown that the position of the hydroxyl substituent of the mono-substituted derivatives of 1 and 10 can be determined by using the coupling constants JH—C—O—H. It is proposed that the vicinal diols of 1 and 10 give 1:1 associations with dimethyl sulfoxide molecules, and the C—H and O—H bonds at position 2 of the mono-substituted derivatives of 1 are approximately anti.

Assignment of the non-exchangeable proton resonances and conformational analysis of oligonucleotide DNA d(TTGGGGTT) by two-dimensional nuclear magnetic resonance methods;

1990 ◽  
Vol 8 (3) ◽  
pp. 246-250
Author(s):  
Yan-Hong Dong ◽  
Wen-Xia Tang ◽  
An-Bang Dai ◽  
Jia-Zhen Wu ◽  
J. H. Boom ◽  
...  
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Conformational Analysis ◽  
Two Dimensional ◽  
Exchangeable Proton ◽  
Proton Resonances ◽  
Nuclear Magnetic

Proton Magnetic Resonance Spectra of Nitronaphthalenes in Dimethylacetamide Solution

1963 ◽  
Vol 16 (6) ◽  
pp. 1108 ◽  
Author(s):  
PR Wells ◽  
PGE Alcorn
Keyword(s):  
Magnetic Resonance ◽  
Nitro Group ◽  
Proximity Effect ◽  
Proton Magnetic Resonance ◽  
Steric Crowding ◽  
Proton Resonances ◽  
The Individual ◽  
Spectral Patterns ◽  
Derivatives Of ◽  
Magnetic Resonance Spectra

Examination of the proton magnetic resonance spectra of some methyl and dimethyl derivatives of 1- and 2-nitronaphthalene has allowed assignments of spectral regions to the various ring protons to be made. The individual proton resonances and overall spectral patterns correspond well with those predicted from studies of the dinitronaphthalenes and dimethylnaphthalenes. Steric crowding in 2-methyl-1-nitronaphthalenes appears to reverse the proximity effect of the nitro group on the peri-hydrogen.

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