scholarly journals Oxidative Modification of Native Protein Residues Using Cerium(IV) Ammonium Nitrate

2011 ◽  
Vol 133 (42) ◽  
pp. 16970-16976 ◽  
Author(s):  
Kristen L. Seim ◽  
Allie C. Obermeyer ◽  
Matthew B. Francis
Keyword(s):  
Ammonium Nitrate ◽  
Oxidative Modification ◽  
Native Protein ◽  
Protein Residues ◽  
Cerium Iv Ammonium Nitrate

Photochemistry of Cerium(IV) Ammonium Nitrate (CAN) in Acetonitrile

2021 ◽  
pp. 113440
Author(s):  
Evgeni M. Glebov ◽  
Vjacheslav P. Grivin ◽  
Victor F. Plyusnin ◽  
Roman G. Fedunov ◽  
Ivan P. Pozdnyakov ◽  
...  
Keyword(s):  
Ammonium Nitrate ◽  
Cerium Iv Ammonium Nitrate

Solid-state regioselective nitration of activated hydroxyaromatics and hydroxycoumarins with cerium (IV) ammonium nitrate

2005 ◽  
Vol 2005 (11) ◽  
pp. 733-735 ◽  
Author(s):  
Nemai C. Ganguly ◽  
Sanjoy Dutta ◽  
Mrityunjoy Datta ◽  
Prithwiraj De
Keyword(s):  
Solid State ◽  
Ammonium Nitrate ◽  
High Efficiency ◽  
Solvent Free ◽  
High Melting ◽  
Microwave Assisted ◽  
Solvent Free Conditions ◽  
High Yields ◽  
Regioselective Nitration ◽  
Cerium Iv Ammonium Nitrate

Predominant ortho-selective mononitration of low-melting and liquid phenols and hydroxycoumarins in moderate to high yields has been accomplished upon grinding with solid cerium (IV) ammonium nitrate (CAN). Microwave-assisted expeditious CAN-mediated nitration of relatively high melting phenols and hydroxycoumarins with high efficiency and selectively under solvent-free conditions has been also developed to address the problems of sluggishness and low yield for these reluctant substrates.

scholarly journals Bioinspired Thiophosphorodichloridate Reagents for Chemoselective Histidine Bioconjugation

2018 ◽  
Author(s):  
Shang Jia ◽  
Christopher Chang
Keyword(s):  
Protein Function ◽  
Living Cells ◽  
Covalent Modification ◽  
Native Protein ◽  
Selective Labeling ◽  
Protein Residues ◽  
Mild Conditions ◽  
Starting Point ◽  
Histidine Phosphorylation ◽  
Site Selective

Site-selective bioconjugation to native protein residues is a powerful tool for protein functionalization, with cysteine and lysine side chains being the most common points for attachment owing to their high nucleophilicity. We now report a strategy for histidine modification using thiophosphorodichloridate reagents that mimic post-translational histidine phosphorylation, enabling fast and selective labeling of protein histidines under mild conditions where various payloads can be introduced via copper-assisted alkyne-azide cycloaddition (CuAAC) chemistry. We establish that these reagents are particularly effective at covalent modification of His-tags, which are common motifs to facilitate protein purification, as illustrated by selective attachment of polyarginine cargoes to enhance the uptake of proteins into living cells. This work provides a starting point for probing and enhancing protein function using histidine-directed chemistry.

An efficient multicomponent, one-pot synthesis of Betti bases catalyzed by cerium (IV) ammonium nitrate (CAN) at ambient temperature

2016 ◽  
Vol 5 (4) ◽  
Author(s):  
Ramadan Ahmed Mekheimer ◽  
Abdullah Mohamed Asiri ◽  
Afaf Mohamed Abdel Hameed ◽  
Reham R. Awed ◽  
Kamal Usef Sadek
Keyword(s):  
Ambient Temperature ◽  
Environmental Pollution ◽  
Ammonium Nitrate ◽  
Room Temperature ◽  
Catalytic Amount ◽  
High Yield ◽  
Reaction Conditions ◽  
One Pot ◽  
Work Up ◽  
Cerium Iv Ammonium Nitrate

AbstractStarting from readily available 2-naphthol, aldehydes, aryl and alkylamines, a variety of Betti bases were efficiently synthesized utilizing a catalytic amount of cerium (IV) ammonium nitrate (CAN) at room temperature. This protocol has advantages of high yield, mild reaction conditions, no environmental pollution, diversity of reactants and simple work up procedure.

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