Fragmentation of Polyfunctional Compounds Recorded Using Automated High-Throughput Desorption Electrospray Ionization

2021 ◽  
Author(s):  
MyPhuong T. Le ◽  
Nicolás M. Morato ◽  
Andreas Kaerner ◽  
Christopher J. Welch ◽  
R. Graham Cooks
Keyword(s):  
Electrospray Ionization ◽  
High Throughput ◽  
Desorption Electrospray Ionization ◽  
Polyfunctional Compounds

scholarly journals Glass surface as strong base, ‘green’ heterogeneous catalyst and degradation reagent

2021 ◽  
Author(s):  
Yangjie Li ◽  
Kai-Hung Huang ◽  
Nicolás M. Morato ◽  
R. Graham Cooks
Keyword(s):  
Mass Spectrometry ◽  
Solid Solution ◽  
Electrospray Ionization ◽  
Chemical Reactions ◽  
High Throughput ◽  
Desorption Electrospray Ionization ◽  
Ionization Mass ◽  
Systematic Screening ◽  
Strong Base ◽  
Glass Surfaces

Systematic screening of accelerated chemical reactions at solid/solution interfaces has been carried out in high-throughput fashion using desorption electrospray ionization mass spectrometry and it provides evidence that glass surfaces accelerate...

High-throughput screening of organic reactions in microdroplets using desorption electrospray ionization mass spectrometry (DESI-MS): hardware and software implementation

2020 ◽  
Vol 12 (28) ◽  
pp. 3654-3669
Author(s):  
Tiago Jose P. Sobreira ◽  
Larisa Avramova ◽  
Botond Szilagyi ◽  
David L. Logsdon ◽  
Bradley P. Loren ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Ionization ◽  
High Throughput ◽  
Electrospray Ionization Mass Spectrometry ◽  
High Throughput Screening ◽  
Desorption Electrospray Ionization ◽  
Ionization Mass Spectrometry ◽  
Ionization Mass ◽  
Desi Ms ◽  
Novel Method

Implementation of a novel method for high-throughput screening of reactions in microdroplets. The reaction and analysis steps are performed simultaneously using desorption electrospray ionization mass spectrometry (DESI-MS) at a rate of up to 1 reaction mixture per second.

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