Cellular Uptake of β-Carotene from Protein Stabilized Solid Lipid Nanoparticles Prepared by Homogenization–Evaporation Method

2014 ◽  
Vol 62 (5) ◽  
pp. 1096-1104 ◽  
Author(s):  
Jiang Yi ◽  
Tina I. Lam ◽  
Wallace Yokoyama ◽  
Luisa W. Cheng ◽  
Fang Zhong
Keyword(s):  
Cellular Uptake ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Evaporation Method ◽  
Solid Lipid ◽  
Β Carotene

Anti-glioma activity and the mechanism of cellular uptake of asiatic acid-loaded solid lipid nanoparticles

2016 ◽  
Vol 500 (1-2) ◽  
pp. 305-315 ◽  
Author(s):  
Tanem Garanti ◽  
Aneta Stasik ◽  
Andrea Julie Burrow ◽  
Mohamed A. Alhnan ◽  
Ka-Wai Wan
Keyword(s):  
Cellular Uptake ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Asiatic Acid ◽  
Solid Lipid

scholarly journals The lipid type affects the in vitro digestibility and β-carotene bioaccessibility of liquid or solid lipid nanoparticles

2020 ◽  
Vol 311 ◽  
pp. 126024 ◽  
Author(s):  
Heloísa Helena de Abreu-Martins ◽  
María Artiga-Artigas ◽  
Roberta Hilsdorf Piccoli ◽  
Olga Martín-Belloso ◽  
Laura Salvia-Trujillo
Keyword(s):  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
In Vitro Digestibility ◽  
Solid Lipid ◽  
Β Carotene

Formulation and characterization of β‐carotene loaded solid lipid nanoparticles

2019 ◽  
Vol 43 (12) ◽  
Author(s):  
Sivakamasundari Selvakumar ◽  
Anu Bhushani Janakiraman ◽  
Maria Leena Michael ◽  
Moses Jeyan Arthur ◽  
Anandharamakrishnan Chinnaswamy
Keyword(s):  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Solid Lipid ◽  
Β Carotene

scholarly journals Solid Lipid Nanoparticles of Albendazole for Enhancing Cellular Uptake and Cytotoxicity against U-87 MG Glioma Cell Lines

Molecules ◽  
2017 ◽  
Vol 22 (11) ◽  
pp. 2040 ◽  
Author(s):  
Gregory Marslin ◽  
Karthik Siram ◽  
Xiang Liu ◽  
Vinoth Khandelwal ◽  
Xiaolei Shen ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cellular Uptake ◽  
Solid Lipid Nanoparticles ◽  
Glioma Cell ◽  
Lipid Nanoparticles ◽  
Solid Lipid ◽  
Glioma Cell Lines

Solid Lipid Nanoparticles for Topical Drug Delivery: Mechanisms, Dosage Form Perspectives, and Translational Status

2020 ◽  
Vol 26 (27) ◽  
pp. 3203-3217
Author(s):  
Mengyang Liu ◽  
Jingyuan Wen ◽  
Manisha Sharma
Keyword(s):  
Drug Delivery ◽  
Cellular Uptake ◽  
Solid Lipid Nanoparticles ◽  
Dosage Form ◽  
Scale Up ◽  
Form Factors ◽  
Skin Penetration ◽  
Lipid Nanoparticles ◽  
Solid Lipid ◽  
Topical Applications

Solid lipid nanoparticles (SLNs) have shown potential as a novel lipid-based drug delivery system for the topical applications of innumerable therapeutic compounds. However, the mechanisms governing the absorption and cellular uptake of SLNs through topical route, along with the mechanism of drug release from SLNs are still ambiguous, and require further investigation. In addition, the selection of an appropriate dosage form/formulation base is essential for ease of application of SLNs and to enhance dermal and transdermal delivery. Upscaling and regulatory approvals are other challenges that may impede the clinical translation of SLNs. Therefore, this review focusses on different mechanisms involved in skin penetration and cellular uptake of SLNs. This is followed by a comprehensive discussion on the physicochemical properties of SLNs including various formulation and dosage form factors, which might influence the absorption of SLNs through the skin. Finally, translational status with respect to scale-up and regulatory aspects are also discussed. This review will be useful to researchers with an interest in topical applications of SLNs for the efficient delivery of drugs and cosmetics.

Sign in / Sign up

Export Citation Format

Share Document