Discovery of a 1H-Benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) Inhibitor of Insulin-like Growth Factor I Receptor Kinase with in Vivo Antitumor Activity

2005 ◽  
Vol 48 (18) ◽  
pp. 5639-5643 ◽  
Author(s):  
Mark Wittman ◽  
Joan Carboni ◽  
Ricardo Attar ◽  
Balu Balasubramanian ◽  
Praveen Balimane ◽  
...  
Keyword(s):  
Growth Factor ◽  
Antitumor Activity ◽  
Insulin Like Growth Factor ◽  
Receptor Kinase ◽  
Factor I ◽  
In Vivo Antitumor Activity ◽  
Growth Factor I

scholarly journals Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo

2007 ◽  
Vol 6 (4) ◽  
pp. 1357-1367 ◽  
Author(s):  
Ta-Jen Liu ◽  
Tiffany LaFortune ◽  
Toshiyuki Honda ◽  
Osamu Ohmori ◽  
Shinji Hatakeyama ◽  
...  
Keyword(s):  
Growth Factor ◽  
Focal Adhesion Kinase ◽  
Focal Adhesion ◽  
Insulin Like Growth Factor ◽  
Receptor Kinase ◽  
Factor I ◽  
Growth Factor I ◽  
Proliferation In Vitro

scholarly journals Antitumor Activity of the Insulin-Like Growth Factor-I Receptor Kinase Inhibitor NVP-AEW541 in Musculoskeletal Tumors

2005 ◽  
Vol 65 (9) ◽  
pp. 3868-3876 ◽  
Author(s):  
Katia Scotlandi ◽  
Maria Cristina Manara ◽  
Giordano Nicoletti ◽  
Pier-Luigi Lollini ◽  
Stella Lukas ◽  
...  
Keyword(s):  
Growth Factor ◽  
Antitumor Activity ◽  
Kinase Inhibitor ◽  
Insulin Like Growth Factor ◽  
Receptor Kinase ◽  
Factor I ◽  
Musculoskeletal Tumors ◽  
Growth Factor I

Relationship Between Growth Hormone in vivo Bioactivity, the Insulin-Like Growth Factor-I System and Bone Mineral Density in Young, Physically Fit Men and Women

2008 ◽  
Author(s):  
B. C. Nindl ◽  
J. R. Pierce ◽  
M. J. Durkot ◽  
A. P. Tuckow ◽  
M. J. Kennett ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Growth Hormone ◽  
Growth Factor ◽  
Bone Mineral ◽  
Insulin Like Growth Factor ◽  
Mineral Density ◽  
Men And Women ◽  
Factor I ◽  
Growth Factor I

scholarly journals Differential association of insulin-like growth factor I mRNA variants with polysomes in vivo.

1991 ◽  
Vol 266 (11) ◽  
pp. 7300-7305
Author(s):  
H L Foyt ◽  
D LeRoith ◽  
C T Roberts
Keyword(s):  
Growth Factor ◽  
Differential Association ◽  
Insulin Like Growth Factor ◽  
Factor I ◽  
Mrna Variants ◽  
Growth Factor I

Ldl-Cholesterol and Insulin-Like Growth Factor-I Are Correlated with in Vivo Aortic Compliance in Normal, Healthy Male Subjects

1993 ◽  
Vol 85 (s29) ◽  
pp. 13P-13P
Author(s):  
KD Hopkdis ◽  
KD Lehdmaidi ◽  
JR Parker ◽  
RG Gosling
Keyword(s):  
Growth Factor ◽  
Ldl Cholesterol ◽  
Insulin Like Growth Factor ◽  
Healthy Male ◽  
Aortic Compliance ◽  
Factor I ◽  
Growth Factor I ◽  
Male Subjects

Potentiation of insulin-like growth factor-I (IGF-I) activity by an antibody: supportive evidence for enhancement of IGF-I bioavailability in vivo by IGF binding proteins.

Endocrinology ◽  
1993 ◽  
Vol 133 (3) ◽  
pp. 1462-1465 ◽  
Author(s):  
C E Stewart ◽  
P C Bates ◽  
T A Calder ◽  
S M Woodall ◽  
J M Pell
Keyword(s):  
Growth Factor ◽  
Binding Proteins ◽  
Insulin Like Growth Factor ◽  
Supportive Evidence ◽  
Igf Binding Proteins ◽  
Factor I ◽  
Igf I ◽  
Igf Binding ◽  
Growth Factor I

Physiology: In-vivo studies on ovarian insulin-like growth factor I concentrations in human preovulatory follicles and human ovarian circulation

1995 ◽  
Vol 10 (6) ◽  
pp. 1341-1345 ◽  
Author(s):  
S. Pellegrini ◽  
B. Fuzzi ◽  
S. Pratesi ◽  
M. Mannelli ◽  
L. Criscuoli ◽  
...  
Keyword(s):  
Growth Factor ◽  
In Vivo Studies ◽  
Insulin Like Growth Factor ◽  
Factor I ◽  
Preovulatory Follicles ◽  
Growth Factor I
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