Synthesis and Evaluation of Novel Carbon-11 Labeled Oxopurine Analogues for Positron Emission Tomography Imaging of Translocator Protein (18 kDa) in Peripheral Organs

2011 ◽  
Vol 54 (17) ◽  
pp. 6040-6049 ◽  
Author(s):  
Katsushi Kumata ◽  
Joji Yui ◽  
Akiko Hatori ◽  
Masayuki Fujinaga ◽  
Kazuhiko Yanamoto ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Positron Emission Tomography Imaging ◽  
Translocator Protein ◽  
Emission Tomography ◽  
Tomography Imaging ◽  
Peripheral Organs ◽  
Positron Emission ◽  
Translocator Protein 18 Kda

Synthesis of two novel [18F]fluorobenzene-containing radiotracers via spirocyclic iodonium ylides and positron emission tomography imaging of translocator protein (18 kDa) in ischemic brain

2018 ◽  
Vol 16 (37) ◽  
pp. 8325-8335 ◽  
Author(s):  
Masayuki Fujinaga ◽  
Katsushi Kumata ◽  
Yiding Zhang ◽  
Akiko Hatori ◽  
Tomoteru Yamasaki ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Positron Emission Tomography Imaging ◽  
Translocator Protein ◽  
Emission Tomography ◽  
Ischemic Brain ◽  
Tomography Imaging ◽  
Positron Emission ◽  
Translocator Protein 18 Kda ◽  
Iodonium Ylides ◽  
The Brain

A new radiotracer for imaging TSPO: Ki, 0.70 nM and no radiolabeled metabolite in the brain.

Positron-Emission-Tomography Imaging of Long-Term Expression of the 18kDa Translocator Protein After Sudden Cardiac Arrest in Rats

Shock ◽  
2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Daniel C. Schroeder ◽  
Erik Popp ◽  
Cathrin Rohleder ◽  
Stefanie Vus ◽  
David de la Puente Bethencourt ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Cardiac Arrest ◽  
Sudden Cardiac Arrest ◽  
Positron Emission Tomography Imaging ◽  
Translocator Protein ◽  
Emission Tomography ◽  
Tomography Imaging ◽  
Positron Emission

[18F]FPBMP: – a potential new positron emission tomography radioligand for imaging of translocator protein (18 kDa) in peripheral organs of rats

RSC Advances ◽  
2015 ◽  
Vol 5 (123) ◽  
pp. 101447-101454 ◽  
Author(s):  
Anjani K. Tiwari ◽  
Joji Yui ◽  
Yiding Zhang ◽  
Masayuki Fujinaga ◽  
Tomoteru Yamasaki ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Translocator Protein ◽  
Emission Tomography ◽  
Peripheral Tissues ◽  
Activated Microglia ◽  
Peripheral Organs ◽  
Positron Emission ◽  
Translocator Protein 18 Kda ◽  
Lung And Kidney

The five transmembrane translocator protein (18 kDa, TSPO) is abundantly expressed in the mitochondria of activated microglia (brain) and peripheral tissues, including those of the heart, lung and kidney.

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