Chlorinolysis of cysteine ethyl ester hydrochloride: an efficient route to certain chloro-amino acid derivatives

1969 ◽  
Vol 34 (11) ◽  
pp. 3703-3705 ◽  
Author(s):  
B. E. Norcross ◽  
R. L. Martin
Keyword(s):  
Amino Acid ◽  
Ethyl Ester ◽  
Amino Acid Derivatives ◽  
Ester Hydrochloride ◽  
Efficient Route

Iron-Catalyzed Oxidative CH/CH Cross-Coupling: An Efficient Route to α-Quaternary α-Amino Acid Derivatives

2013 ◽  
Vol 52 (49) ◽  
pp. 12942-12945 ◽  
Author(s):  
Kaizhi Li ◽  
Guangying Tan ◽  
Jingsheng Huang ◽  
Feijie Song ◽  
Jingsong You
Keyword(s):  
Amino Acid ◽  
Cross Coupling ◽  
Amino Acid Derivatives ◽  
Efficient Route

ChemInform Abstract: Amidocarbonylation - An Efficient Route to Amino Acid Derivatives

ChemInform ◽  
2010 ◽  
Vol 31 (20) ◽  
pp. no-no
Author(s):  
Matthias Beller ◽  
Markus Eckert
Keyword(s):  
Amino Acid ◽  
Amino Acid Derivatives ◽  
Efficient Route

SYNTHESIS OF A NEW α-AMINO ACID, S-METHYL-β,β-DIMETHYLCYSTEINE

1946 ◽  
Vol 24b (1) ◽  
pp. 28-36 ◽  
Author(s):  
Kenneth Savard ◽  
Edwin M. Richardson ◽  
Gordon A. Grant
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Methyl Ester ◽  
Ethyl Ester ◽  
Ester Hydrochloride ◽  
First Time

A new sulphur-containing α-amino acid, S-methyl-β,β-dimethylcysteine has been prepared from S-benzyl-β,β-dimethylcysteine. These two compounds and the intermediate β,β-dimethylcysteine may be of physiological importance.S-Benzyl-β,β-dimethylcysteine has been prepared by the addition of benzyl mercaptan to α-benzoylamino-β,β-dimethylacrylic acid, its azlactone, and methyl ester, followed by hydrolysis.In addition to the above three new sulphur-containing α-amino acids, the following compounds are described, as far as the authors are aware, for the first time: methyl α-benzoylamino-β,β-dimethylacrylate, S-benzyl-N-benzoyl-β,β-dimethylcysteine and its methyl ester, the hydantoin of S-benzyl-β,β-dimethylcysteine, and S-benzyl-β,β-dimethylcysteine ethyl ester hydrochloride, and helianthate.

ChemInform Abstract: Iron-Catalyzed Oxidative C-H/C-H Cross-Coupling: An Efficient Route to α-Quaternary α-Amino Acid Derivatives.

ChemInform ◽  
2014 ◽  
Vol 45 (19) ◽  
pp. no-no
Author(s):  
Kaizhi Li ◽  
Guangying Tan ◽  
Jingsheng Huang ◽  
Feijie Song ◽  
Jingsong You
Keyword(s):  
Amino Acid ◽  
Cross Coupling ◽  
Amino Acid Derivatives ◽  
Efficient Route

Enantioselective synthesis of cyclic quaternary α-amino acid derivatives by chiral phosphoric acid catalysis

2017 ◽  
Vol 15 (28) ◽  
pp. 6033-6041 ◽  
Author(s):  
Lei Wang ◽  
Abdul Rahman ◽  
Xufeng Lin
Keyword(s):  
Amino Acid ◽  
Phosphoric Acid ◽  
Acid Catalysis ◽  
Enantioselective Synthesis ◽  
Amino Acid Derivatives ◽  
Chiral Phosphoric Acid ◽  
Efficient Route ◽  
Quaternary Stereocenter ◽  
High Yields ◽  
Phosphoric Acids

Development of highly enantioselective aza-Friedel–Crafts reaction of N-sulfonyl cyclic ketimines with indoles catalyzed by chiral phosphoric acids, providing an efficient route to indole-containing chiral cyclic α-amino acid derivatives bearing quaternary stereocenter in high yields and up to 98% enantioselectivity.

Effect of cysteine ethyl ester supplements on wool growth rate

1985 ◽  
Vol 36 (5) ◽  
pp. 709 ◽  
Author(s):  
BC Radcliffe ◽  
PI Hynd ◽  
NJ Benevenga ◽  
AR Egan
Keyword(s):  
Growth Rate ◽  
Amino Acid ◽  
Continuous Infusion ◽  
Ethyl Ester ◽  
Control Period ◽  
Basal Diet ◽  
Sulfur Amino Acid ◽  
Ester Hydrochloride ◽  
Control Groups ◽  
Wool Growth

L-Cysteine ethyl ester hydrochloride (CEE) was evaluated as a dietary sulfur amino acid supplement for increasing wool growth rate. In Experiment 1, eight sheep were offered 800 g chopped lucerne hay daily and wool growth was measured over a three-week control period. These sheep were then given a continuous infusion of either CEE per rumen, CEE per abomasum, cysteine per abomasum or continued on the basal diet alone, for three weeks, and wool growth was measured again. All supplements were equivalent to 25 mmol/day. Wool growth rate on tattooed patches in sheep given CEE per rumen or abomasum increased 67% and 75% respectively above the rates prior to infusion, while that of animals given cysteine increased 45%. Wool growth rate in the control sheep increased by only 15% in the same period. In Experiment 2, wool growth was measured in 24 sheep offered 800 g/day lucerne chaff, and again when CEE, cystine, or Na2SO4, each providing 21 mmol S/day, were combined with mineral mix and offered with the feed. CEE and cystine increased wool production by 1.9 g/sheep/day (P < 0.01) and 1.0 g/day (P < 0.05), respectively, above that measured in the control groups (nil- or Na2SO4- supplemented) which did not differ.

Iron-Catalyzed Oxidative CH/CH Cross-Coupling: An Efficient Route to α-Quaternary α-Amino Acid Derivatives

2013 ◽  
Vol 125 (49) ◽  
pp. 13180-13183 ◽  
Author(s):  
Kaizhi Li ◽  
Guangying Tan ◽  
Jingsheng Huang ◽  
Feijie Song ◽  
Jingsong You
Keyword(s):  
Amino Acid ◽  
Cross Coupling ◽  
Amino Acid Derivatives ◽  
Efficient Route

scholarly journals Sulfur containing activated hydantions. Synthesis and screening some novel benzylidenehydantoins amino acids derivatives

2001 ◽  
Vol 66 (1) ◽  
pp. 17-21 ◽  
Author(s):  
Ragab El-Sayed
Keyword(s):  
Amino Acid ◽  
Sulfonyl Chloride ◽  
Acid Methyl Ester ◽  
Chlorosulfonic Acid ◽  
Amino Acid Derivatives ◽  
Coupling Reactions ◽  
Ester Hydrochloride ◽  
Acid Methyl ◽  
Amino Acid Methyl Ester ◽  
Sulfur Containing

5-Benzylidenehydantoin reacts with chlorosulfonic acid to give the corresponding p-sulfonyl chloride 1. Condensation with nucleophiles gives amino acid derivatives 2-7. Coupling reactions of some amino acid derivatives (2-6) with amino acid methyl ester hydrochloride in THF-Et3N medium using the dicyclohexylcarbodiimide method (DCC) furnish the desired dipeptidemethyl esters 8-12. The spectral data of the synthesized compounds are briefly discussed.

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