Monodispersed Mesoporous Silica Nanoparticles with Very Large Pores for Enhanced Adsorption and Release of DNA

The development of new styrene-based hyper-crosslinked nanocomposites (HCLN) containing mesoporous silica nanoparticles (MSN) is reported here as a new strategy to obtain functional high surface area materials with an enhanced hydrophilic character. The HCLN composition, morphology and porous structure were analyzed using a multi-technique approach. The HCLN displayed a high surface area (above 1600 m2/g) and higher microporosity than the corresponding hyper-crosslinked neat resin. The enhanced adsorption properties of the HCLN towards polar organic dyes was demonstrated through the adsorption of a reactive dye, Remazol Brilliant Blue R (RB). In particular, the HCLN containing 5phr MSN showed the highest adsorption capacity of RB.

Download Full-text

AMINE MODIFIED MESOSTRUCTURED SILICA NANO PARTICLES ENHANCED ADSORPTION OF PHENOL

Jurnal Teknologi ◽

10.11113/jt.v75.5156 ◽

2015 ◽

Vol 75 (6) ◽

Author(s):

N.F.M. Salleh ◽

A.A. Jalil ◽

S. Triwahyono ◽

S.N. Nordin ◽

N.H.N. Kamarudin ◽

...

Keyword(s):

Mesoporous Silica ◽

Silica Nanoparticles ◽

Adsorption Energy ◽

Pore Volume ◽

Mesoporous Silica Nanoparticles ◽

Nano Particles ◽

Amine Group ◽

Adsorptive Removal ◽

Mesostructured Silica ◽

Enhanced Adsorption

Mesoporous silica nanoparticles (MSN) were synthesized and modified with (3-aminopropyl) triethoxysilane (APTES) using co-condensation (co-MSN) and post-grafting (post-MSN) methods. Both modification methods seem to alter the crystallinity, surface area, and pore volume as compared to the unmodified MSN. The activity of all MSNs was tested for the adsorptive removal of phenol. Co-MSN showed significantly good adsorptivity towards 10 mg L-1 of phenols, followed by post-MSN and MSN. It was found that the highest activity of co-MSN was resulted from the additional higher adsorption energy from the quaternary alkylammonium groups (Si–C–C–C–[N+–(CH3)3]) of cationic template and also from the amine group of the APTES functionalization, which showed more advantages as compared to post-MSN and MSN.

Download Full-text

Adsorption and Release of Sulfamethizole from Mesoporous Silica Nanoparticles Functionalised with Triethylenetetramine

International Journal of Molecular Sciences ◽

10.3390/ijms22147665 ◽

2021 ◽

Vol 22 (14) ◽

pp. 7665

Author(s):

Cristina Carucci ◽

Nicola Scalas ◽

Andrea Porcheddu ◽

Marco Piludu ◽

Maura Monduzzi ◽

...

Keyword(s):

Mesoporous Silica ◽

Silica Nanoparticles ◽

Surface Area ◽

Intermolecular Interactions ◽

Mesoporous Silica Nanoparticles ◽

Release Kinetics ◽

Lower Surface ◽

Burst Release ◽

Vis Spectroscopy ◽

Adsorption And Release

Mesoporous silica nanoparticles (MSN) were synthesised and functionalised with triethylenetetramine (MSN-TETA). The samples were fully characterised (transmission electron microscopy, small angle X-ray scattering, Fourier transform infrared spectroscopy, thermogravimetric analysis, zeta potential and nitrogen adsorption/desorption isotherms) and used as carriers for the adsorption of the antimicrobial drug sulphamethizole (SMZ). SMZ loading, quantified by UV–Vis spectroscopy, was higher on MSN-TETA (345.8 mg g−1) compared with bare MSN (215.4 mg g−1) even in the presence of a lower surface area (671 vs. 942 m2 g−1). The kinetics of SMZ adsorption on MSN and MSN-TETA followed a pseudo-second-order model. The adsorption isotherm is described better by a Langmuir model rather than a Temkin or Freundlich model. Release kinetics showed a burst release of SMZ from bare MSN samples (k1 = 136 h−1) in contrast to a slower release found with MSN-TETA (k1 = 3.04 h−1), suggesting attractive intermolecular interactions slow down SMZ release from MSN-TETA. In summary, the MSN surface area did not influence SMZ adsorption and release. On the contrary, the design of an effective drug delivery system must consider the intermolecular interactions between the adsorbent and the adsorbate.

Download Full-text

Elucidation of acid strength effect on ibuprofen adsorption and release by aluminated mesoporous silica nanoparticles

RSC Advances ◽

10.1039/c4ra16761a ◽

2015 ◽

Vol 5 (38) ◽

pp. 30023-30031 ◽

Cited By ~ 18

Author(s):

N. H. N. Kamarudin ◽

A. A. Jalil ◽

S. Triwahyono ◽

M. R. Sazegar ◽

S. Hamdan ◽

...

Keyword(s):

Mesoporous Silica ◽

Silica Nanoparticles ◽

Mesoporous Silica Nanoparticles ◽

Acid Strength ◽

Ft Ir ◽

Adsorption And Release ◽

Strength Effect

Mesoporous silica nanoparticles (MSN) with 1–10 wt% loading of aluminum (Al) were prepared and characterized by XRD, N2 physisorption, 29Si and 27Al NMR, FT-IR and FT-IR preadsorbed pyridine.

Download Full-text

Adsorption and Release of 5-Fluorouracil (5FU) from Mesoporous Silica Nanoparticles

Materials Today Proceedings ◽

10.1016/j.matpr.2019.11.202 ◽

2019 ◽

Vol 19 ◽

pp. 1722-1729 ◽

Cited By ~ 4

Author(s):

Nur Syazaliyana Azali ◽

Nur Hidayatul Nazirah Kamarudin ◽

Ainul Rasyidah Abdul Rahim ◽

Norzaidhatul Syifa'a Jamal Nasir ◽

Sharifah Najiha Timmiati ◽

...

Keyword(s):

Mesoporous Silica ◽

Silica Nanoparticles ◽

Mesoporous Silica Nanoparticles ◽

Adsorption And Release

Download Full-text

Influence of mesopore size and peptide aggregation on the adsorption and release of a model antimicrobial peptide onto/from mesoporous silica nanoparticles in vitro

Molecular Systems Design & Engineering ◽

10.1039/c7me00059f ◽

2017 ◽

Vol 2 (4) ◽

pp. 393-400 ◽

Cited By ~ 10

Author(s):

Katharina Braun ◽

Alexander Pochert ◽

Marlena Gerber ◽

Heinz Fabian Raber ◽

Mika Lindén

Keyword(s):

Mesoporous Silica ◽

Antimicrobial Peptide ◽

Silica Nanoparticles ◽

Mesoporous Silica Nanoparticles ◽

Peptide Aggregation ◽

Adsorption And Release

The interplay between mesopore size and degree of peptide aggregation controls both calcitonin adsorption onto and release from mesoporous silica nanoparticles.

Download Full-text