Supramolecular Liquid-Crystalline Side-Chain Polymers Built through a Molecular Recognition Process by Double Hydrogen Bonds

1995 ◽  
Vol 28 (26) ◽  
pp. 8875-8876 ◽  
Author(s):  
Takashi Kato ◽  
Masahisa Nakano ◽  
Tomonori Moteki ◽  
Toshiyuki Uryu ◽  
Seiji Ujiie
2018 ◽  
Vol 74 (7) ◽  
pp. 690-694 ◽  
Author(s):  
Ian W. Windsor ◽  
Ronald T. Raines

Crystal structures of inactive variants of HIV-1 protease bound to peptides have revealed how the enzyme recognizes its endogenous substrates. The best of the known substrates is, however, a nonnatural substrate that was identified by directed evolution. The crystal structure of the complex between this substrate and the D25N variant of the protease is reported at a resolution of 1.1 Å. The structure has several unprecedented features, especially the formation of additional hydrogen bonds between the enzyme and the substrate. This work expands the understanding of molecular recognition by HIV-1 protease and informs the design of new substrates and inhibitors.


1996 ◽  
Vol 29 (27) ◽  
pp. 8734-8739 ◽  
Author(s):  
Takashi Kato ◽  
Hideyuki Kihara ◽  
Seiji Ujiie ◽  
Toshiyuki Uryu ◽  
Jean M. J. Fréchet

1985 ◽  
Vol 40 (5-6) ◽  
pp. 457-459 ◽  
Author(s):  
Dieter G. Müller ◽  
Wilhelm Boland ◽  
Lothar Jaenicke ◽  
Günter Gassmann

Abstract Ectocarpene, (+)-(6S)-(1Z-butenyl)-2,5-cycloheptadiene, is the mating pherom one of the three distantly related seaweeds Ectocarpus siliculosus, Sphacelaria rigidula and Adenocystis utricularis. Analogu es of this pheromone, dif­fering in position and π-electron density of the double bond in the C4-side chain, were synthesized and assayed for biological activity. The results suggest, that the fundamen­tal molecular recognition process is conservative in all species, while receptor dynamics and -topologies have been modified by individual developments and expressions dur­ing plant phylogeny.


2015 ◽  
Vol 3 (33) ◽  
pp. 8526-8534 ◽  
Author(s):  
Miao Yan ◽  
Jun Tang ◽  
He-Lou Xie ◽  
Bin Ni ◽  
Hai-Liang Zhang ◽  
...  

Self-healing liquid crystalline elastomers were fabricated by hydrogen-bonding and the hydrogen bonds in this system played an important role both in self-healing property and the liquid crystalline phase behavior.


1998 ◽  
Vol 31 (11) ◽  
pp. 3551-3555 ◽  
Author(s):  
Takashi Kato ◽  
Osamu Ihata ◽  
Seiji Ujiie ◽  
Masatoshi Tokita ◽  
Junji Watanabe

2017 ◽  
Vol 8 (21) ◽  
pp. 3286-3293 ◽  
Author(s):  
Bin Mu ◽  
Xingtian Hao ◽  
Jian Chen ◽  
Qian Li ◽  
Chunxiu Zhang ◽  
...  

Well-prepared side-chain discotic liquid crystal polymers with shorter spacers in ordered columnar phases are fascinating and promising cost-effective, solution-processable organic semiconducting materials for various potential optoelectronic device applications.


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