Total Synthesis of Elastin Peptide Using High Pressure–Liquid Phase Synthesis Assisted by a Soluble Tag Strategy

2014 ◽  
Vol 16 (24) ◽  
pp. 6448-6451 ◽  
Author(s):  
Yohei Okada ◽  
Shoichi Hosoya ◽  
Hidenobu Suzuki ◽  
Kazuhiro Chiba
Molecules ◽  
2021 ◽  
Vol 26 (14) ◽  
pp. 4224
Author(s):  
Fusong Wu ◽  
Jie Yu ◽  
Jiawei Meng ◽  
Yian Guo ◽  
Tao Ye

The first total synthesis of the thiazole-containing cyclic depsipeptide pagoamide A, is detailed. The longest linear sequence of the liquid-phase synthesis comprises 9 long linear steps from simple known starting materials, which led to the unambiguous structural confirmation of pagoamide A.


2021 ◽  
Vol 17 ◽  
pp. 2924-2931
Author(s):  
Haipin Zhou ◽  
Zihan Rui ◽  
Yiming Yang ◽  
Shengtao Xu ◽  
Yutian Shao ◽  
...  

Hoshinoamides A, B and C, linear lipopeptides, were isolated from the marine cyanobacterium Caldora penicillata, with potent antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum. Herein, we describe the first total synthesis of hoshinoamide A by the combination of liquid-phase and solid-phase peptide synthesis. Liquid-phase synthesis is to improve the coupling yield of ʟ-Val3 and N-Me-ᴅ-Phe2. Connecting other amino acids efficiency and convergence is achieved by solid-state synthesis. Our synthetic strategy could synthesize the target peptide in high yield with good purity


2021 ◽  
pp. 126225
Author(s):  
Rutuja Bhusari ◽  
Jean-Sébastien Thomann ◽  
Jérôme Guillot ◽  
Renaud Leturcq

2021 ◽  
Vol 218 (15) ◽  
pp. 2170045
Author(s):  
Andrii Vasin ◽  
Dmytro Kysil ◽  
Stanislav Sevostianov ◽  
Oksana Isaieva ◽  
Galyna Rudko ◽  
...  

Author(s):  
Guillaume Gouget ◽  
Damien Bregiroux ◽  
Rémi Grosjean ◽  
David Montero ◽  
Stefan Maier ◽  
...  

2021 ◽  
Author(s):  
Alexander Egeberg ◽  
Lara-P. Faden ◽  
Anna Zimina ◽  
Jan-Dierk Grunwaldt ◽  
Dagmar Gerthsen ◽  
...  
Keyword(s):  
One Pot ◽  

Zerovalent niobium, Nb(0), and tantalum, Ta(0), nanoparticles are prepared via a one-pot, liquid-phase synthesis. Thus, NbCl5/TaCl5 are dissolved in pyridine and reduced by lithium pyridinyl. Deep black suspensions of very...


1994 ◽  
Vol 49 (24) ◽  
pp. 4563-4578 ◽  
Author(s):  
David Parra ◽  
Javier Tejero ◽  
Fidel Cunill ◽  
Montserrat Iborra ◽  
José F. Izquierdo

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