IGF-I and retinoic acid regulate the distribution pattern of IGFBPs synthesized by the canine mammary tumor cell line CMT-U335

1999 ◽  
Vol 54 (1) ◽  
pp. 11-23 ◽  
Author(s):  
Marja A. Oosterlaken-dijksterhuis ◽  
Marijke M. Kwant ◽  
Adri Slob ◽  
Eva Hellmén ◽  
Jan A. Mol
Keyword(s):  
Retinoic Acid ◽  
Tumor Cell ◽  
Distribution Pattern ◽  
Cell Line ◽  
Mammary Tumor ◽  
Tumor Cell Line ◽  
Canine Mammary Tumor ◽  
Mammary Tumor Cell ◽  
Mammary Tumor Cell Line ◽  
Igf I

scholarly journals Synergistic growth inhibitory effect of deracoxib with doxorubicin against a canine mammary tumor cell line, CMT-U27

2016 ◽  
Vol 78 (4) ◽  
pp. 657-668 ◽  
Author(s):  
Tülay BAKIREL ◽  
Fulya Üstün ALKAN ◽  
Oya ÜSTÜNER ◽  
Suzan ÇINAR ◽  
Funda YILDIRIM ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Line ◽  
Mammary Tumor ◽  
Tumor Cell Line ◽  
Inhibitory Effect ◽  
Canine Mammary Tumor ◽  
Growth Inhibitory Effect ◽  
Mammary Tumor Cell ◽  
Mammary Tumor Cell Line ◽  
Growth Inhibitory

scholarly journals Establishment of 5-Fluorouracil-resistant canine mammary tumor cell line

2017 ◽  
Vol 20 (1) ◽  
pp. 103-110 ◽  
Author(s):  
B. Zhou ◽  
D. Zhang ◽  
S. M. Pei ◽  
H. Zhang ◽  
H. C. Du ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Line ◽  
Mammary Tumor ◽  
Tumor Cell Line ◽  
Parental Cell ◽  
Parental Cell Line ◽  
Canine Mammary Tumor ◽  
Mammary Tumor Cell ◽  
Mammary Tumor Cell Line

Abstract Canine mammary tumors are the most common neoplasms in intact female dogs. The surgery cannot always solve the problem, chemotherapy are recommend to these patients. However, chemotherapy could always fail because of multidrug resistance (MDR). Through stepwise increasing 5-Fluorouracil (5-FU) concentration in the culture medium, a 5-FU-resistant canine mammary tumor cell line CMT7364/5-FU was established to disclose the molecular mechanism of the drug resistance. Cell morphology, cell sensitivity to drugs, growth curves, expression of proteins, and chemo-sensitivity in vivo were compared between the parental cell line and resistant cell line. As compared it to its parental cell line (CMT7364), CMT7364/5-FU showed different morphology, cross-resistant to other chemo-drugs and a prolonged population doubling time (PDT). The drug efflux pump proteins (ABCB1 and ABCG2) in CMT7364/5-FU were up-regulated. In vivo, the similar result revealed that CMT7364/5-FU cell line was more resistant to 5-FU. In conclusion, a 5-FU-resistant canine mammary tumor cell line (CMT7364/5-FU) was successfully established, it can serve as a good model for researching the mechanism of MDR and screening effective agents to reverse drug resistance.

Establishment and characterization of a new murine mammary tumor cell line, balb/c-MC

1987 ◽  
Vol 23 (11) ◽  
pp. 755-758 ◽  
Author(s):  
Junji Morimoto ◽  
Shunsuke Imai ◽  
Yuzo Taniguchi ◽  
Yoshihiko Tsubura ◽  
Howard L. Hosick
Keyword(s):  
Tumor Cell ◽  
Cell Line ◽  
Mammary Tumor ◽  
Tumor Cell Line ◽  
Mammary Tumor Cell ◽  
Mammary Tumor Cell Line ◽  
Murine Mammary Tumor

scholarly journals Rosiglitazone inhibits metastasis development of a murine mammary tumor cell line LMM3

BMC Cancer ◽  
2008 ◽  
Vol 8 (1) ◽  
Author(s):  
Gabriela Magenta ◽  
Ximena Borenstein ◽  
Romina Rolando ◽  
María Adela Jasnis
Keyword(s):  
Tumor Cell ◽  
Cell Line ◽  
Mammary Tumor ◽  
Tumor Cell Line ◽  
Mammary Tumor Cell ◽  
Mammary Tumor Cell Line ◽  
Murine Mammary Tumor ◽  
Metastasis Development
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