International public awareness of peripheral artery disease

VASA ◽  
2021 ◽  
pp. 1-7
Author(s):  
Rupert Bauersachs ◽  
Marianne Brodmann ◽  
Christopher Clark ◽  
Sebastian Debus ◽  
Marco De Carlo ◽  
...  
Keyword(s):  
Peripheral Artery Disease ◽  
Public Awareness ◽  
Age Groups ◽  
Lower Limbs ◽  
Common Condition ◽  
Peripheral Artery ◽  
Health And Disease ◽  
Artery Disease ◽  
Gender Based ◽  
Delays In Diagnosis

Summary: Background: Peripheral artery disease (PAD) of the lower limbs is a common condition with considerable global burden. Some country-specific studies suggest low levels of public awareness. To our knowledge public awareness of PAD has never been assessed simultaneously in several countries worldwide. Patients and methods: This was an international, general public, internet-based quantitative survey assessing vascular health and disease understanding. Questionnaires included 23 closed-ended multiple-choice, Likert scale and binary choice questions. Data were collected from 9,098 survey respondents from nine countries in Europe, North and Latin America during May-June 2018. Results: Overall, familiarity with PAD was low (57% of respondents were “not at all familiar”, and 9% were “moderately” or “very familiar”). Knowledge about PAD health consequences was limited, with 55% of all respondents not being aware of limb consequences of PAD. There were disparities in PAD familiarity levels between countries; highest levels of self-reported awareness were in Germany and Poland where 13% reported to be “very” or “moderately” familiar with PAD, and lowest in Scandinavian countries (5%, 3% and 2% of respondents in Norway, Sweden and Denmark, respectively). There were disparities in awareness according to age. Respondents aged 25–34 were most familiar with PAD, with 12% stating that they were “moderately” or “very” familiar with the condition, whereas those aged 18–24 were the least familiar with PAD (7% “moderately” or “very” familiar with PAD). In the 45–54, 55–64 and 65+ age groups, 9% said they were “moderately” or “very” familiar with the term. There was no important gender-based difference in PAD familiarity. Conclusions: On an international level, public self-reported PAD awareness is low, even though PAD is a common condition with considerable burden. Campaigns to increase PAD awareness are needed to reduce delays in diagnosis and to motivate people to control PAD risk factors.

Concordance of Glucose-Based and of HbA1c-Based Diagnoses of Diabetes in Patients with Peripheral Artery Disease—A Comparison between Two Age Groups

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1522-P
Author(s):  
CHRISTOPH H. SAELY ◽  
ALEXANDER VONBANK ◽  
CHRISTINE HEINZLE ◽  
DANIELA ZANOLIN ◽  
BARBARA LARCHER ◽  
...  
Keyword(s):  
Peripheral Artery Disease ◽  
Age Groups ◽  
Peripheral Artery ◽  
Artery Disease ◽  
Two Age Groups

Abstract 15937: Gender Disparities in Presentation and Outcomes for Patients Undergoing Endovascular Lower Extremity Interventions for Peripheral Artery Disease

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Elizabeth M Lancaster ◽  
Bian Wu ◽  
Joel Ramirez ◽  
James Iannuzzi ◽  
Michael S Conte ◽  
...  
Keyword(s):  
Lower Extremity ◽  
Hospital Mortality ◽  
Peripheral Artery Disease ◽  
Severe Disease ◽  
Functional Decline ◽  
Multivariable Analysis ◽  
National Database ◽  
Peripheral Artery ◽  
Artery Disease ◽  
Gender Based

Introduction: Although data suggests higher rates of functional decline and inferior outcomes in women compared to men after interventions for peripheral artery disease (PAD), women remain underrepresented in contemporary studies. We used a large national database to better understand gender-based differences in presentation and outcomes for patients undergoing endovascular treatment for PAD. Methods: Patients in the Vascular Quality Initiative (VQI) database that underwent lower extremity (LE) endovascular interventions for symptomatic PAD from 2010-2019 were included. Descriptive statistics and multivariable analysis were performed. Results: 128,688 patients (40% female) underwent endovascular LE interventions for symptomatic PAD. Women were more likely to have chronic limb threatening ischemia compared to men (54% vs 51%) and more likely to have a preoperative ABI <0.4 (20% vs 14%). Compared to men, women were older (mean [SD]: 68 [11] vs 70 [12]), more likely to be Black (19% vs 14%), and less likely to be smokers (34% vs 36%), diabetic (50% vs 54%), have CAD (28% vs 35%), or be on dialysis (8% vs 9%) (Table 1). Women were less likely to have exclusively infrapopliteal interventions (8% vs 14%) compared to men (p<0.001 for all). Despite shorter procedural times in women, female gender was an independent predictor of in hospital mortality (OR 1.25, 95% CI 1.09-1.44) in a hierarchical multivariable model adjusting for age, race, smoking, and comorbidities. Women were more likely to be discharged to a rehab or nursing home (11% vs 10%, p< 0.001) and less likely to be taking a statin medication (73% vs 78%, p<0.001). Conclusions: Compared to men, women undergoing endovascular LE interventions for PAD are older, present with more severe disease, and have higher adjusted rates of in hospital mortality. More aggressive screening and medical treatment for PAD in women is needed to address these gender-based differences in disease presentation and clinical outcomes.

scholarly journals Epidemiology of Peripheral Artery Disease of Lower Limbs among Workers to Cotonou in 2013

2017 ◽  
Vol 05 (02) ◽  
Author(s):  
Codjo HL ◽  
Sonou A ◽  
Wanvoegbe A ◽  
Doyigbe M ◽  
Adjagba P ◽  
...  
Keyword(s):  
Peripheral Artery Disease ◽  
Lower Limbs ◽  
Peripheral Artery ◽  
Artery Disease

scholarly journals A rare case of sigmoid colon cancer in which the lower limbs received collateral blood flow from the inferior mesenteric artery owing to peripheral artery disease

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Kyoichi Kihara ◽  
Hiromu Horie ◽  
Kozo Miyatani ◽  
Masayuki Endo ◽  
Tomoyuki Matsunaga ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Sigmoid Colon ◽  
Peripheral Artery Disease ◽  
Mesenteric Artery ◽  
Inferior Mesenteric Artery ◽  
Limb Ischemia ◽  
Lower Limbs ◽  
Sigmoid Colon Cancer ◽  
Peripheral Artery ◽  
Artery Disease

Abstract Background Colorectal cancer and peripheral artery disease are common conditions in older adults and may coexist in this population. Lymph node dissection along the inferior mesenteric artery is a vital procedure in cases of left-sided colorectal cancer. However, the inferior mesenteric artery may show a collateral blood pathway in rare cases of peripheral artery disease. We report a case of advanced sigmoid colon cancer in which the lower limbs received inferior mesenteric artery flow owing to asymptomatic peripheral artery disease. The possibility of catastrophic lower-limb ischemia because of complete mesenteric excision with ligation of the inferior mesenteric artery was a matter of concern in this case. Case presentation A 73-year-old man with asymptomatic peripheral artery disease was diagnosed with stage IIIB advanced sigmoid colon cancer. Angiography using a balloon-occlusion catheter revealed that his lower limbs received prominent inferior mesenteric artery blood flow through a collateral pathway. Therefore, interventional radiologists and cardiovascular surgeons evaluated the indications for endovascular stents or bypass grafts. The patient also had dilated cardiomyopathy, so the cardiovascular physicians evaluated his tolerance in the worst-case scenario of a colorectal anastomotic leak. The patient underwent axillofemoral artery bypass and two-stage laparoscopic sigmoid colectomy without anastomosis. The postoperative course was uneventful, and he resumed his job within a month after the resection. Conclusions Although collateral flow from the inferior mesenteric artery is rare in patients with peripheral artery disease, a few case reports have described fatal lower-limb ischemia following anterior resection. The perioperative multidisciplinary evaluation enabled us to understand the patient’s condition and risks, and allowed successful cancer treatment without ischemia of the lower limbs.

scholarly journals Effects of Programmed Kinesiologic Stimulus to Hemodynamics at Peripheral Artery Disease of Lower Limbs

2014 ◽  
Vol 22 (6) ◽  
pp. 368
Author(s):  
Abel Baltic ◽  
Izet Radjo ◽  
Ifet Mahmutovic ◽  
Indira Mahmutovic
Keyword(s):  
Peripheral Artery Disease ◽  
Lower Limbs ◽  
Peripheral Artery ◽  
Artery Disease

Restenosis after endovascular revascularization in peripheral artery disease

VASA ◽  
2015 ◽  
Vol 44 (4) ◽  
pp. 257-270 ◽  
Author(s):  
Nasser M. Malyar ◽  
Holger Reinecke ◽  
Eva Freisinger
Keyword(s):  
Peripheral Artery Disease ◽  
Primary Patency ◽  
Lower Limbs ◽  
Lesion Length ◽  
Success Rates ◽  
Peripheral Artery ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Endovascular Revascularization ◽  
Artery Disease

Abstract. Endovascular revascularization (EVR) plays a leading role in the therapy of peripheral artery disease. The acute success rates of EVR in all anatomic territories and of all TASC lesions are excellent (> 95%). However, the occurrence of restenoses after EVR such as percutaneous transluminal angioplasty and particularly after stenting, poses a substantial limitation to the success of the procedure. Influenced by patient’s comorbidities, the severity of arteriosclerotic disease, lesion length and morphology as well as the techniques and devices used for EVR, the long-term outcome of EVR deteriorates markedly from the aortoiliac to the infrapopliteal segments of the lower limbs. The development of drug-coated balloons and drug-eluting stents reduced the occurrence of restenosis leading to considerably improved primary patency rates in the femoropopliteal segments. This review aims to provide an overview about the underlying mechanisms and current relevance of the various options in the field of EVR with regard to the rate of restenosis.

Lower extremity peripheral artery disease: a basic approach

2020 ◽  
Vol 81 (3) ◽  
pp. 1-9
Author(s):  
Keith A Chan ◽  
Alex Junia
Keyword(s):  
Peripheral Artery Disease ◽  
Lifestyle Changes ◽  
Lower Limbs ◽  
Peripheral Artery ◽  
Early Administration ◽  
Pressure Index ◽  
Cardiovascular Morbidity And Mortality ◽  
Artery Disease ◽  
High Degree ◽  
Progressive Disorder

Peripheral artery disease of the lower limbs is a chronically progressive disorder characterised by the presence of occlusive lesions in the medium and large arteries that result in symptoms secondary to insufficient blood flow to the lower extremities. It is both a manifestation of systemic atherosclerosis and a marker of increased cardiovascular morbidity and mortality. Because of its highly heterogenous clinical picture, a detailed history and physical assessment, a high degree of suspicion for peripheral artery disease and the use of the ankle–brachial pressure index is essential to identify patients with peripheral artery disease. This will allow early administration of basic pharmacotherapy and lifestyle changes to reduce cardiovascular events, minimise claudication symptoms and enable optimal revascularisation to prevent loss of limb function.

Extracorporeal Blood Oxygenation and Ozonation (EBOO): A Controlled Trial in Patients with Peripheral Artery Disease

2005 ◽  
Vol 28 (10) ◽  
pp. 1039-1050 ◽  
Author(s):  
N. Di Paolo ◽  
V. Bocci ◽  
D.P. Salvo ◽  
F. Palasciano ◽  
M. Biagioli ◽  
...  
Keyword(s):  
Peripheral Artery Disease ◽  
Controlled Trial ◽  
Well Being ◽  
Skin Lesions ◽  
Blood Oxygenation ◽  
Lower Limbs ◽  
Controlled Clinical Trial ◽  
Peripheral Artery ◽  
Extracorporeal Blood ◽  
Artery Disease

Background Since 1990 our group has been using extracorporeal circulation to ozonate blood by an original method, known as extracorporeal blood oxygenation and ozonation (EBOO), with the aim of amplifying the results observed with ozone autohemotherapy. Objective To verify the hypothesis that EBOO improves the skin lesions typical of peripheral artery disease (PAD) patients. Methods Twenty-eight patients with PAD were randomized to receive EBOO or intravenous prostacyclin in a controlled clinical trial. The primary efficacy parameters were regression of skin lesions and pain, and improvement in quality of life and vascularisation. Results Patients treated with EBOO showed highly significant regression of skin lesions with respect to patients treated with prostacyclin. Other parameters that were significantly different in the two groups of patients were pain, pruritus, heavy legs and well-being. No significant differences in vascularisation of the lower limbs before and after treatment were found in either group. No side effects or complications were recorded during the 210 EBOO treatments. Conclusion EBOO was much more effective than prostacyclin for treating skin lesions in PAD patients and also had a positive effect on patient general condition without any apparent change in arterial circulation. This suggests other mechanisms of action of EBOO.

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