scholarly journals Cancer patients with major depressive disorder: Testing a biobehavioral/cognitive behavior intervention.

2011 ◽  
Vol 79 (2) ◽  
pp. 253-260 ◽  
Author(s):  
Brittany M. Brothers ◽  
Hae-Chung Yang ◽  
Daniel R. Strunk ◽  
Barbara L. Andersen
2018 ◽  
Vol 17 (04) ◽  
pp. 436-440 ◽  
Author(s):  
Oscar Rodríguez-Mayoral ◽  
Bárbara Rodríguez-Ortíz ◽  
Leticia Ascencio-Huertas ◽  
Adriana Peña-Nieves ◽  
Emma Verástegui ◽  
...  

AbstractObjectiveDepression in palliative advanced cancer patients is common, but often goes unrecognized. One of the first steps toward improving detection is the development of tools that are valid in the specific language and setting in which they are to be used. The Brief Edinburgh Depression Scale (BEDS) is a sensitive case-finding tool for depression in advanced cancer patients that was developed in the United Kingdom. There are no validated instruments to identify depression in Mexican palliative patients. Our aim was to validate the Spanish-language version of the BEDS in Mexican population with advanced cancer.MethodWe conducted a cross-sectional study with outpatients from the palliative care unit at the Instituto Nacional de Cancerología in Mexico City. The Mexican BEDS was validated against a semistructured psychiatric clinical interview according to the Diagnostic and Statistical Manual of Mental Disorders, 5th edition, classification criteria for major depressive disorder. The interviewer was blind to the BEDS score at the time of the assessment.ResultSeventy subjects completed the scale and interview. Women represented 71.4% of the sample and median age of subjects was 56.5 years (range, 20–85 years). The prevalence of major depressive disorder according to the psychiatric interview was 20%. The most valid cutoff for defining a case of depression was a score ≥5 of 18 on the Mexican BEDS, which gave a sensitivity of 85.7% and specificity of 62.5%. The scale's Cronbach's alpha was 0.71.Significance of resultsMajor depressive disorder is frequent in Mexican palliative patients. The Spanish-language Mexican version of the BEDS is the first valid case-finding tool in advanced cancer patients in this setting.


2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 9015-9015
Author(s):  
Kelly Marie Trevino ◽  
Karen Fasciano ◽  
Holly Gwen Prigerson

9015 Background: Suicide rates in YA cancer patients are higher than in the general population. Although cancer is associated with a four-fold increase in the likelihood of a suicide attempt, little is known about suicidality in YAs with cancer. This study examined rates and clinical risk factors associated with suicidality in a sample of YAs with advanced cancer. Methods: Structured interviews were conducted between 4/2010 and 9/2011 with 70 YA advanced cancer patients (range 20-40 yrs, M=33.97, SD=5.61) receiving care at the Dana-Farber Cancer Institute. Validated measures assessed suicidality (i.e., Yale Evaluation of Suicidality), quality of life, major depressive disorder, grief over cancer-related losses, and social support. Scores on the suicidality measure were dichotomized into positive screen = 1 and negative screen = 0. Chi-square, t-test, and logistic regression analyses evaluated the relationship between suicidality and participant characteristics and psychosocial variables, controlling for confounding variables. Results: Over one-fifth (21.4%) of the sample screened positive for suicidality. Female gender χ2(1, N = 70) = 4.95, p = .026), breast compared with other cancer diagnosis χ2(1, N = 70) = 5.66, p = .017), and better performance status (t(68) = 3.13, p < .01) were associated with lower rates of suicidality. Participants who met criteria for current (OR [95% CI] 8.67 [1.78, 42.22]) or lifetime major depressive disorder (5.38 [1.60, 18.12]) endorsed higher rates of suicidality. Better overall (.97 [.94, .99]), psychological (.93 [.87, .94]), and existential quality of life (.91 [.85, .98]) were associated with reduced suicidality risk. More severe grief was associated with greater risk (1.15 [1.04, 1.28]) whereas greater social support was associated with lower suicidality risk (.85 [.74, .97]). Conclusions: YAs with advanced cancer reported higher rates of suicidality than observed in other age groups. Developmentally targeted interventions that promote physical function, effectively treat depression, improve quality of life and reduce grief, and provide opportunities for social support may reduce rates of and risk for suicidality in this population.


2021 ◽  
Vol 2 (6) ◽  
pp. 101-113
Author(s):  
Tania Qamar ◽  
Saralah Devi Mariamdaran Chethiyar ◽  
Nabisah binti Ibrahim

Purpose. The present research was conducted to examine the effectiveness of intervention based Cognitive Behavior Therapy (CBT) module in treating signs of depression among females with major depressive disorder. Method. Qusai experimental (pretest-posttest) research design was used in the present study. Females (age range; 25-40 years) suffering from moderate level of major depressive disorder were selected through random and stratified sampling strategy. Demographic sheet, DSM-5 checklist, visual analogue scale and beck depression inventory were used as an assessment measure in this study. Results. Statistical analysis revealed significant results. Findings showed that cognitive behavioral therapy alleviated depression symptoms among females with major depressive disorder. Females who received cognitive behavioural therapies scored lower on the Beck Depression Inventory than females who did not get any interventions, according to the findings. This suggests that Cognitive Behavioral Therapy (CBT) is useful for ladies suffering from serious depression. Novelty/Originality of The Study. The main goals of the first treatment interview develop a warm collaborative therapy connection, identify particular problem sets and associated goals, psycho-educate the patient about the cognitive model and vicious cycle that keeps depression alive, and give the patient an idea about future treatment methods. CBT is divided into three sections: beginning treatment, behavioural interventions, and working with negative automatic thoughts, used cognitive restructuring and ending sessions. Implications. The current treatment will demonstrate significant decreases in depressive symptoms and endorsement of faulty metacognitive beliefs between baseline and posttreatment, as well as, in the follow-up.


2016 ◽  
Vol 34 (3) ◽  
pp. 236-245 ◽  
Author(s):  
Isabelle M. Rosso ◽  
William D.S. Killgore ◽  
Elizabeth A. Olson ◽  
Christian A. Webb ◽  
Rena Fukunaga ◽  
...  

2006 ◽  
Vol 20 (2) ◽  
pp. 159-170 ◽  
Author(s):  
Leslie Karwoski ◽  
Genevieve M. Garratt ◽  
Stephen S. Ilardi

Cognitive-behavior therapy (CBT) has received extensive empirical support as an efficacious intervention for the acute treatment of major depressive disorder and the prevention of depressive relapse. Nevertheless, many patients do not respond favorably to CBT, and the specific active ingredients of CBT remain unclear. With its emphasis on identifying and cultivating individual strengths, however, positive psychology appears to have considerable potential to enhance the efficacy of CBT and to help clarify the processes that mediate its salubrious effects. We outline existing areas of conceptual and technical overlap between CBT and positive psychology, and discuss how CBT may be extended and improved through the incorporation of positive psychological principles.


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