Is loneliness in emerging adults increasing over time? A preregistered cross-temporal meta-analysis and systematic review.

ObjectiveTo explore whether physical activity is inversely associated with the onset of depression, we quantified the cumulative association of customary physical activity with incident depression and with an increase in subclinical depressive symptoms over time as reported from prospective observational studies.DesignSystematic review and meta-analysis.Data sourcesMEDLINE, PsycINFO, PsycARTICLES and CINAHL Complete databases, supplemented by Google Scholar.Eligibility criteriaProspective cohort studies in adults, published prior to January 2020, reporting associations between physical activity and depression.Study appraisal and synthesisMultilevel random-effects meta-analysis was performed adjusting for study and cohort or region. Mixed-model meta-regression of putative modifiers.ResultsSearches yielded 111 reports including over 3 million adults sampled from 11 nations in five continents. Odds of incident cases of depression or an increase in subclinical depressive symptoms were reduced after exposure to physical activity (OR, 95% CI) in crude (0.69, 0.63 to 0.75; I2=93.7) and adjusted (0.79, 0.75 to 0.82; I2=87.6) analyses. Results were materially the same for incident depression and subclinical symptoms. Odds were lower after moderate or vigorous physical activity that met public health guidelines than after light physical activity. These odds were also lower when exposure to physical activity increased over time during a study period compared with the odds when physical activity was captured as a single baseline measure of exposure.ConclusionCustomary and increasing levels of moderate-to-vigorous physical activity in observational studies are inversely associated with incident depression and the onset of subclinical depressive symptoms among adults regardless of global region, gender, age or follow-up period.

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In vivo praziquantel efficacy of Schistosoma japonicum over time: a systematic review and meta-analysis

Acta Tropica ◽

10.1016/j.actatropica.2021.106048 ◽

2021 ◽

pp. 106048

Author(s):

Qiu-Fu Yu ◽

Jie-Ying Zhang ◽

Meng-Tao Sun ◽

Man-Man Gu ◽

Hui-Ying Zou ◽

...

Keyword(s):

Systematic Review ◽

Schistosoma Japonicum ◽

Meta Analysis ◽

Over Time

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Global epidemiology of SARS-CoV-2 infection: a systematic review and meta-analysis of standardized population-based seroprevalence studies, Jan 2020-Oct 2021

10.1101/2021.12.14.21267791 ◽

2021 ◽

Author(s):

Isabel Bergeri ◽

Mairead Whelan ◽

Harriet Ware ◽

Lorenzo Subissi ◽

Anthony Nardone ◽

...

Keyword(s):

Systematic Review ◽

Meta Analysis ◽

Grey Literature ◽

Population Based ◽

Control Measures ◽

Middle Income ◽

Global Epidemiology ◽

Using Data ◽

Demographic Subgroups ◽

Over Time

Background COVID-19 case data underestimates infection and immunity, especially in low- and middle-income countries (LMICs). We meta-analyzed standardized SARS-CoV-2 seroprevalence studies to estimate global seroprevalence. Objectives/Methods We conducted a systematic review and meta-analysis, searching MEDLINE, Embase, Web of Science, preprints, and grey literature for SARS-CoV-2 seroprevalence studies aligned with the WHO UNITY protocol published between 2020-01-01 and 2021-10-29. Eligible studies were extracted and critically appraised in duplicate. We meta-analyzed seroprevalence by country and month, pooling to estimate regional and global seroprevalence over time; compared seroprevalence from infection to confirmed cases to estimate under-ascertainment; meta-analyzed differences in seroprevalence between demographic subgroups; and identified national factors associated with seroprevalence using meta-regression. PROSPERO: CRD42020183634. Results We identified 396 full texts reporting 736 distinct seroprevalence studies (41% LMIC), including 355 low/moderate risk of bias studies with national/sub-national scope in further analysis. By April 2021, global SARS-CoV-2 seroprevalence was 26.1%, 95% CI [24.6-27.6%]. Seroprevalence rose steeply in the first half of 2021 due to infection in some regions (e.g., 18.2% to 45.9% in Africa) and vaccination and infection in others (e.g., 11.3% to 57.4% in the Americas high-income countries), but remained low in others (e.g., 0.3% to 1.6% in the Western Pacific). In 2021 Q1, median seroprevalence to case ratios were 1.9:1 in HICs and 61.9:1 in LMICs. Children 0-9 years and adults 60+ were at lower risk of seropositivity than adults 20-29. In a multivariate model using data pre-vaccination, more stringent public health and social measures were associated with lower seroprevalence. Conclusions Global seroprevalence has risen considerably over time and with regional variation, however much of the global population remains susceptible to SARS-CoV-2 infection. True infections far exceed reported COVID-19 cases. Standardized seroprevalence studies are essential to inform COVID-19 control measures, particularly in resource-limited regions.

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Effects of Mindfulness Meditation Intervention on Depressive Symptoms in Emerging Adults: A Systematic Review and Meta-Analysis

Journal of Integrative and Complementary Medicine ◽

10.1089/jicm.2021.0036 ◽

2022 ◽

Vol 28 (1) ◽

pp. 6-24

Author(s):

Chuntana Reangsing ◽

Christina Lauderman ◽

Joanne Kraenzle Schneider

Keyword(s):

Systematic Review ◽

Depressive Symptoms ◽

Emerging Adults ◽

Mindfulness Meditation ◽

Meta Analysis

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Changes in delta‐9‐tetrahydrocannabinol (THC) and cannabidiol (CBD) concentrations in cannabis over time: systematic review and meta‐analysis

Addiction ◽

10.1111/add.15253 ◽

2020 ◽

Cited By ~ 1

Author(s):

Tom P. Freeman ◽

Sam Craft ◽

Jack Wilson ◽

Stephan Stylianou ◽

Mahmoud ElSohly ◽

...

Keyword(s):

Systematic Review ◽

Meta Analysis ◽

Over Time

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Well-Being and Romantic Relationships: A Systematic Review in Adolescence and Emerging Adulthood

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph16132415 ◽

2019 ◽

Vol 16 (13) ◽

pp. 2415 ◽

Cited By ~ 7

Author(s):

Mercedes Gómez-López ◽

Carmen Viejo ◽

Rosario Ortega-Ruiz

Keyword(s):

Systematic Review ◽

Romantic Relationships ◽

Emerging Adulthood ◽

Emerging Adults ◽

Meta Analysis ◽

Well Being ◽

The Other ◽

The One ◽

Definition Of ◽

The Relationship

Adolescence and emerging adulthood are both stages in which romantic relationships play a key role in development and can be a source of both well-being and negative outcomes. However, the limited number of studies prior to adulthood, along with the multiplicity of variables involved in the romantic context and the considerable ambiguity surrounding the construct of well-being, make it difficult to reach conclusions about the relationship between the two phenomena. This systematic review synthesizes the results produced into this topic over the last three decades. A total of 112 studies were included, following the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) guidelines. On the one hand, these works revealed the terminological heterogeneity in research on well-being and the way the absence of symptoms of illness are commonly used to measure it, while on the other hand, they also showed that romantic relationships can be an important source of well-being for both adolescents and emerging adults. The findings underline the importance of providing a better definition of well-being, as well as to attribute greater value to the significance of romantic relationships. Devoting greater empirical, educational, and community efforts to romantic development in the stages leading up to adulthood are considered necessary actions in promoting the well-being of young people.

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