Early Predictors of Later Creative Achievements

The article presents the predictors of placental dysfunction on the early stage of pregnancy. The objective: the search for prognostic markers and criteria for the occurrence of placental insufficiency in the early stages of the gestational process to optimize the pregnancy and labor with improved perinatal outcomes. Patients and methods. To solve this goal in the period from 2013 to 2015 were conducted a comprehensive survey of 334 pregnant women, which depending on the peculiarities of pregnancy and childbirth were divided into groups. The control group consisted of 236 pregnant women with uncomplicated gestational period, no morphological signs of placental dysfunction. The study group included 98 patients with a complicated pregnancy who had revealed violations of the fetal-placental relations, which was confirmed by morphological examination of the placenta in the postpartum period. Results. It was found that pregnant women with placental insufficiency in the first trimester of pregnancy have higher levels of interleukin-1B (IL-1v) and interleukin-3 (IL-3) in comparison with physiological pregnancy, as well as there is a direct significant correlation between IL-1v and pulsative index (PI) in the spiral (r=0.84) and uterine artery (r=0.77), and the inverse correlation between the level of IL-3 and PI in the terminal branches of the umbilical artery (r=-0.69). Verified an inverse relationship between the concentration of endothelin-1, the level of vascular endothelial growth factor (r=-0.87) and placental growth factor (r=-0.73), and also a direct link between the content of endothelin-1 and PI in spiral arteries (r=0.89), uterine artery (r=0.83) and the terminal branches of the umbilical artery (r=0.79). Conclusion. Thus, it is proven that early predictors of placental dysfunction can be considered the concentration of endothelin-1, vascular endothelial growth factor, placental growth factor, interleukin-1, interleukin-3, and the indices of pulsative index. Key words: placental dysfunction, predictors, endothelin-1, vascular endothelial growth factor, placental growth factor, interleukin, pulsative index.

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Faculty Opinions recommendation of Early predictors of outcome in comatose survivors of ventricular fibrillation and non-ventricular fibrillation cardiac arrest treated with hypothermia: a prospective study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1120090.576224 ◽

2008 ◽

Author(s):

Anne-Cornelie de Pont

Keyword(s):

Cardiac Arrest ◽

Ventricular Fibrillation ◽

Prospective Study ◽

Predictors Of Outcome ◽

Early Predictors ◽

A Prospective Study

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Local Neighborhoods as Early Predictors of Innovation Adoption

SSRN Electronic Journal ◽

10.2139/ssrn.1545245 ◽

2010 ◽

Cited By ~ 2

Author(s):

Jacob Goldenberg

Keyword(s):

Innovation Adoption ◽

Early Predictors

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Early Predictors of 15-Year End-Stage Renal Disease in Hypertensive Patients

Hypertension ◽

10.1161/01.hyp.25.4.587 ◽

1995 ◽

Vol 25 (4) ◽

pp. 587-594 ◽

Cited By ~ 197

Author(s):

H. Mitchell Perry ◽

J. Philip Miller ◽

Jane Rossiter Fornoff ◽

Jack D. Baty ◽

Mohinder P. Sambhi ◽

...

Keyword(s):

Renal Disease ◽

End Stage Renal Disease ◽

Hypertensive Patients ◽

Early Predictors ◽

Stage Renal Disease ◽

End Stage

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Calorimetric analysis of ice onset temperature during cryoablation: a model approach to identify early predictors of effective applications

Scientific Reports ◽

10.1038/s41598-021-95204-2 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Elena Campagnoli ◽

Andrea Ballatore ◽

Valter Giaretto ◽

Matteo Anselmino

Keyword(s):

Cooling Rate ◽

Latent Heat ◽

Bovine Liver ◽

Onset Temperature ◽

Ice Formation ◽

Scanning Calorimetry ◽

Calorimetric Analysis ◽

Early Predictors ◽

Latent Heat Capacity ◽

Model Approach

AbstractAim of the present study is to analyze thermal events occurring during cryoablation. Different bovine liver samples underwent freezing cycles at different cooling rate (from 0.0075 to 25 K/min). Ice onset temperature and specific latent heat capacity of the ice formation process were measured according to differential scanning calorimetry signals. A computational model of the thermal events occurring during cryoablation was compiled using Neumann’s analytical solution. Latent heat (#1 = 139.8 ± 7.4 J/g, #2 = 147.8 ± 7.9 J/g, #3 = 159.0 ± 4.1 J/g) of all liver samples was independent of the ice onset temperature, but linearly dependent on the water content. Ice onset temperature was proportional to the logarithm of the cooling rate in the range 5 ÷ 25 K/min (#3a = − 12.2 °C, #3b = − 16.2 °C, #3c = − 6.6 °C at 5K/min; #3a = − 16.5 °C, #3b = − 19.3 °C, #3c = − 11.6 °C at 25 K/min). Ice onset temperature was associated with both the way in which the heat involved into the phase transition was delivered and with the thermal gradient inside the tissue. Ice onset temperature should be evaluated in the early phase of the ablation to tailor cryoenergy delivery. In order to obtain low ice trigger temperatures and consequent low ablation temperatures a high cooling rate is necessary.

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