Discrimination Ability and Effects of Belief on Natural Versus Synthetic Odorant Evaluation

2000 ◽  
Author(s):  
Rachel S. Herz
2021 ◽  
Vol 2021 (5) ◽  
Author(s):  
Garvita Agarwal ◽  
Lauren Hay ◽  
Ia Iashvili ◽  
Benjamin Mannix ◽  
Christine McLean ◽  
...  

Abstract A framework is presented to extract and understand decision-making information from a deep neural network (DNN) classifier of jet substructure tagging techniques. The general method studied is to provide expert variables that augment inputs (“eXpert AUGmented” variables, or XAUG variables), then apply layerwise relevance propagation (LRP) to networks both with and without XAUG variables. The XAUG variables are concatenated with the intermediate layers after network-specific operations (such as convolution or recurrence), and used in the final layers of the network. The results of comparing networks with and without the addition of XAUG variables show that XAUG variables can be used to interpret classifier behavior, increase discrimination ability when combined with low-level features, and in some cases capture the behavior of the classifier completely. The LRP technique can be used to find relevant information the network is using, and when combined with the XAUG variables, can be used to rank features, allowing one to find a reduced set of features that capture part of the network performance. In the studies presented, adding XAUG variables to low-level DNNs increased the efficiency of classifiers by as much as 30-40%. In addition to performance improvements, an approach to quantify numerical uncertainties in the training of these DNNs is presented.


2014 ◽  
Vol 44 (13) ◽  
pp. 2739-2748 ◽  
Author(s):  
J. T. Kantrowitz ◽  
N. Scaramello ◽  
A. Jakubovitz ◽  
J. M. Lehrfeld ◽  
P. Laukka ◽  
...  

BackgroundBoth language and music are thought to have evolved from a musical protolanguage that communicated social information, including emotion. Individuals with perceptual music disorders (amusia) show deficits in auditory emotion recognition (AER). Although auditory perceptual deficits have been studied in schizophrenia, their relationship with musical/protolinguistic competence has not previously been assessed.MethodMusical ability was assessed in 31 schizophrenia/schizo-affective patients and 44 healthy controls using the Montreal Battery for Evaluation of Amusia (MBEA). AER was assessed using a novel battery in which actors provided portrayals of five separate emotions. The Disorganization factor of the Positive and Negative Syndrome Scale (PANSS) was used as a proxy for language/thought disorder and the MATRICS Consensus Cognitive Battery (MCCB) was used to assess cognition.ResultsHighly significant deficits were seen between patients and controls across auditory tasks (p < 0.001). Moreover, significant differences were seen in AER between the amusia and intact music-perceiving groups, which remained significant after controlling for group status and education. Correlations with AER were specific to the melody domain, and correlations between protolanguage (melody domain) and language were independent of overall cognition.DiscussionThis is the first study to document a specific relationship between amusia, AER and thought disorder, suggesting a shared linguistic/protolinguistic impairment. Once amusia was considered, other cognitive factors were no longer significant predictors of AER, suggesting that musical ability in general and melodic discrimination ability in particular may be crucial targets for treatment development and cognitive remediation in schizophrenia.


Physics ◽  
2021 ◽  
Vol 3 (2) ◽  
pp. 320-351
Author(s):  
Serge Nagorny

Recent progress in Cs2HfCl6 (CHC) crystal production achieved within the last five years is presented. Various aspects have been analyzed, including the chemical purity of raw materials, purification methods, optimization of the growth and thermal conditions, crystal characterization, defect structure, and internal radioactive background. Large volume, crack-free, and high quality CHC crystals with an ultimate scintillating performance were produced as a result of such extensive research and development (R & D) program. For example, the CHC crystal sample with dimensions ∅23 × 30 mm3 demonstrates energy resolution of 3.2% FWHM at 662 keV, the relative light output at the level of 30,000 ph/MeV and excellent linearity down to 20 keV. Additionally, this material exhibits excellent pulse shape discrimination ability and low internal background of less than 1 Bq/kg. Furthermore, attempts to produce a high quality CHC crystal resulted in research on this material optimization by constitution of either alkali ions (Cs to Tl), or main element (Hf to Zr), or halogen ions (Cl to Br, I, or their mixture in different ratio), as well as doping with various active ions (Te4+, Ce3+, Eu3+, etc.). This leads to a range of new established scintillating materials, such as Tl2HfCl6, Tl2ZrCl6, Cs2HfCl4Br2, Cs2HfCl3Br3, Cs2ZrCl6, and Cs2HfI6. To exploit the whole potential of these compounds, detailed studies of the material’s fundamental properties, and understanding of the variety of the luminescence mechanisms are required. This will help to understand the origin of the high light yield and possible paths to further extend it. Perspectives of CHC crystals and related materials as detectors for rare nuclear processes are also discussed.


Author(s):  
Jennifer Nitsch ◽  
Jordan Sack ◽  
Michael W. Halle ◽  
Jan H. Moltz ◽  
April Wall ◽  
...  

Abstract Purpose We aimed to develop a predictive model of disease severity for cirrhosis using MRI-derived radiomic features of the liver and spleen and compared it to the existing disease severity metrics of MELD score and clinical decompensation. The MELD score is compiled solely by blood parameters, and so far, it was not investigated if extracted image-based features have the potential to reflect severity to potentially complement the calculated score. Methods This was a retrospective study of eligible patients with cirrhosis ($$n=90$$ n = 90 ) who underwent a contrast-enhanced MR screening protocol for hepatocellular carcinoma (HCC) screening at a tertiary academic center from 2015 to 2018. Radiomic feature analyses were used to train four prediction models for assessing the patient’s condition at time of scan: MELD score, MELD score $$\ge $$ ≥ 9 (median score of the cohort), MELD score $$\ge $$ ≥ 15 (the inflection between the risk and benefit of transplant), and clinical decompensation. Liver and spleen segmentations were used for feature extraction, followed by cross-validated random forest classification. Results Radiomic features of the liver and spleen were most predictive of clinical decompensation (AUC 0.84), which the MELD score could predict with an AUC of 0.78. Using liver or spleen features alone had slightly lower discrimination ability (AUC of 0.82 for liver and AUC of 0.78 for spleen features only), although this was not statistically significant on our cohort. When radiomic prediction models were trained to predict continuous MELD scores, there was poor correlation. When stratifying risk by splitting our cohort at the median MELD 9 or at MELD 15, our models achieved AUCs of 0.78 or 0.66, respectively. Conclusions We demonstrated that MRI-based radiomic features of the liver and spleen have the potential to predict the severity of liver cirrhosis, using decompensation or MELD status as imperfect surrogate measures for disease severity.


2021 ◽  
pp. 003022282199132
Author(s):  
Fernando E. Padovan-Neto ◽  
Sherman A. Lee ◽  
Rayanne Poletti Guimarães ◽  
Lívea Dornela Godoy ◽  
Hugo Bononi Costa ◽  
...  

This study examined the psychometric properties of a Brazilian adapted version of the Coronavirus Anxiety Scale (CAS-BR) in a sample of adults in Brazil. Confirmatory factor analyses demonstrated that the CAS-BR produces a reliable (α = .84), unidimensional construct whose structure was shown to be invariant across gender, race, and age. However, some items of the CAS-BR were stronger indicators of the coronavirus anxiety construct for women and younger adults. Although the CAS-BR demonstrated evidence of discrimination ability for functional impairment (AUC = .77), Youden indexes were low to identify a clinical cut-score. Construct validity was demonstrated with correlations between CAS-BR scores and measures of functional impairment, generalized anxiety, and depression. Exploratory analyses revealed that CAS-BR total scores were higher among women and participants with a history of anxiety disorder. These findings are consistent with previous investigations and support the validity of CAS-BR for measuring coronavirus anxiety with Brazilian adults.


2015 ◽  
Vol 2015 ◽  
pp. 1-13 ◽  
Author(s):  
Xianghong Che ◽  
Min Feng ◽  
Hao Jiang ◽  
Jia Song ◽  
Bei Jia

Inland surface water is essential to terrestrial ecosystems and human civilization. Accurate mapping of surface water dynamic is vital for both scientific research and policy-driven applications. MODIS provides twice observation per day, making it perfect for monitoring temporal water dynamic. Although MODIS provides two bands at 250 m resolution, accurately deriving water area always depends on observations from the spectral bands with 500 m resolution, which limits its discrimination ability over small lakes and rivers. The paper presents an automated method for downscaling the 500 m MODIS surface reflectance (SR) to 250 m to improve the spatial discrimination of water body extraction. The method has been tested at Co Ngoin and Co Bangkog in Qinghai-Tibet plateau. The downscaled SR and the derived water bodies were compared to SR and water body mapped from Landsat-7 ETM+ images were acquired on the same date. Consistency metrics were calculated to measure their agreement and disagreement. The comparisons indicated that the downscaled MODIS SR showed significant improvement over the original 500 m observations when compared with Landsat-7 ETM+ SR, and both commission and omission errors were reduced in the derived 250 m water bodies.


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