PRODH Mutation Reduces Social Interaction: An Animal Model of Schizophrenia

2009 ◽  
Author(s):  
Noah L. Lazar ◽  
Shiva Singh ◽  
Donald P. Cain
Keyword(s):  
Animal Model ◽  
Social Interaction

Synergistic effect of galantamine with risperidone on impairment of social interaction in phencyclidine-treated mice as a schizophrenic animal model

2007 ◽  
Vol 52 (4) ◽  
pp. 1179-1187 ◽  
Author(s):  
Dayong Wang ◽  
Yukihiro Noda ◽  
Yuan Zhou ◽  
Atsumi Nitta ◽  
Hiroshi Furukawa ◽  
...  
Keyword(s):  
Animal Model ◽  
Social Interaction ◽  
Synergistic Effect

An Animal Model for Psychopharmacological Research with Relevance to Psychiatry

1973 ◽  
Vol 18 (2) ◽  
pp. 139-146
Author(s):  
John E. Peachey ◽  
Harvey C. Stancer
Keyword(s):  
Animal Model ◽  
Social Interaction ◽  
Animal Models ◽  
Environmental Factors ◽  
Animal Species ◽  
Drug Effect ◽  
Squirrel Monkeys ◽  
Yield Information ◽  
Behavioural Characteristics ◽  
Clinical Methods

The concept is presented that animal models for psychopharmacological research should take into account clinical methods if they are to yield information which is relevant to psychiatry. Animal species with appropriate behavioural characteristics should be selected, drugs should be administered chronically and groups of animals should be used if social interaction is to be observed. Some of the relevant pharmacological, behavioural and environmental factors are presented and illustrated with examples taken from a study on groups of squirrel monkeys who had received parachlorophenylalanine or alpha-methylparatyrosine to lower specific brain amines. It is noted that social interaction may affect the expression of the drug effect.

An animal model of dyadic social interaction: Influence of isolation, competition, and shock-induced aggression

1982 ◽  
Vol 8 (2) ◽  
pp. 116-121 ◽  
Author(s):  
Richard H. Schuster ◽  
Howard Rachlin ◽  
Meni Rom ◽  
Barry D. Berger
Keyword(s):  
Animal Model ◽  
Social Interaction

scholarly journals Psilocybin rescues sociability deficits in an animal model of autism

2020 ◽  
Author(s):  
Irene Mollinedo-Gajate ◽  
Chenchen Song ◽  
Marcos Sintes-Rodriguez ◽  
Tobias Whelan ◽  
Anaïs Soula ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Valproic Acid ◽  
Animal Model ◽  
Social Interaction ◽  
Mouse Model ◽  
Therapeutic Agent ◽  
Autism Spectrum ◽  
The Core ◽  
Acute Response ◽  
The Social

AbstractAutism spectrum disorder (ASD) is characterized by core deficits in social interaction. The classic serotonergic psychedelic psilocybin has been suggested as a therapeutic agent that may ameliorate in the core symptomology of ASD. We found that the acute response to psilocybin was attenuated in the prenatal valproic acid exposure mouse model of ASD, and importantly, psilocybin rescued the social behavioural abnormalities present in these ASD model mice.

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