Time Uncertainty and the Estimation of Time-intervals

Nature ◽  
1962 ◽  
Vol 195 (4838) ◽  
pp. 311-312 ◽  
Author(s):  
R. DAVIS
2019 ◽  
Vol 31 (12) ◽  
pp. 1796-1826 ◽  
Author(s):  
Andrea Nani ◽  
Jordi Manuello ◽  
Donato Liloia ◽  
Sergio Duca ◽  
Tommaso Costa ◽  
...  

During the last two decades, our inner sense of time has been repeatedly studied with the help of neuroimaging techniques. These investigations have suggested the specific involvement of different brain areas in temporal processing. At least two distinct neural systems are likely to play a role in measuring time: One is mainly constituted of subcortical structures and is supposed to be more related to the estimation of time intervals below the 1-sec range (subsecond timing tasks), and the other is mainly constituted of cortical areas and is supposed to be more related to the estimation of time intervals above the 1-sec range (suprasecond timing tasks). Tasks can then be performed in motor or nonmotor (perceptual) conditions, thus providing four different categories of time processing. Our meta-analytical investigation partly confirms the findings of previous meta-analytical works. Both sub- and suprasecond tasks recruit cortical and subcortical areas, but subcortical areas are more intensely activated in subsecond tasks than in suprasecond tasks, which instead receive more contributions from cortical activations. All the conditions, however, show strong activations in the SMA, whose rostral and caudal parts have an important role not only in the discrimination of different time intervals but also in relation to the nature of the task conditions. This area, along with the striatum (especially the putamen) and the claustrum, is supposed to be an essential node in the different networks engaged when the brain creates our sense of time.


2005 ◽  
Vol 128 (3) ◽  
pp. 691-695 ◽  
Author(s):  
Yongliang Zhu ◽  
Prabhakar R. Pagilla

Adaptive estimation of time-varying parameters in linearly parametrized systems is considered. The estimation time is divided into small intervals; in each interval the time-varying parameter is approximated by a time polynomial with unknown coefficients. A condition for resetting of the parameter estimate at the beginning of each interval is derived; the condition guarantees that the estimate of the time-varying parameter is continuous and also allows for the coefficients of the polynomial to be different in various time intervals. A modified version of the least-squares algorithm is provided to estimate the time-varying parameters. Stability of the proposed algorithm is shown and discussed. Simulation results on an example are given to validate the proposed method.


2011 ◽  
Vol 26 (S2) ◽  
pp. 1677-1677 ◽  
Author(s):  
R.F. Nasyrova ◽  
L.S. Sotnikova

In result of clinical-psychopathological examination of 100 women suffering from hysteromyoma we have identified as compared with portion of patients without mental disturbances, specific weight of women with mental disorders (47%) and with pre-nosological manifestations (43%) predominated (р < 0,05), from them 21% met definitions of psychoadaptive state and 22% - psychodisadaptive status (PDAS). Study of distribution of prevalence of variants of PDAS has revealed predominance in the examined of asthenic register (8%), where basic manifestations was feeling of fatigue, increasing to the end of the day, pains in muscles, sensation of apathy. Psychovegetative variant was revealed in 6% patients and was represented by paroxysmal vegetative dysfunctions, transient headaches, and sleep disturbance. Dysthymic variant characterized by emotional lability in the kind of irritability, feeling of uneasiness and mental discomfort, has been revealed in 5%, and dysmnestic variant manifesting by short-term changes in the sphere of attention, orientation in familiar setting, erroneous estimation of time intervals was diagnosed in 3% of women. Revealed mental disturbances included four clusters: neurotic, stress-related and somatoform disorders (F40–48) have been revealed in 29% of examined women; affective, predominately of depressive spectrum (F32–34.1) - in 9%; personality disorders and behavioral disorders at mature age (F60–61) - in 3% and behavioral syndromes associated with physiological disturbances and physical factors (F50–52) - in 6%. Presented data demonstrate high prevalence of mental disturbances in female patients with hysteromyoma that, complicating severity of state of women and decreasing adaptive abilities, considerably worsens quality of life and efficacy of treatment measures.


2012 ◽  
Vol 24 (5) ◽  
pp. 809-821 ◽  
Author(s):  
Jeremia Heinik

ABSTRACTBackground: Accuracy of estimation of time-intervals has received marginal attention in psychogeriatrics. We examined presumed differences in this time measure in participants with dementia (PWD) versus participants without dementia (PWoutD), further subdivided into specific diagnoses and performance subgroups. We also studied its demographic, clinical, and cognitive correlates and predictors. A diagnostic role was hypothesized.Methods: Forty-three individuals (27 PWD: 16 dementia of the Alzheimer's type (DAT), 11 vascular dementia (VaD); 16 PWoutD: 10 major depressive disorder (MDD), 6 normal) were interviewed with the Cambridge Examination for Mental Disorders of the Elderly – Revised (CAMDEX-R) that permits the registration of this time measure. Demographic, clinical, and cognitive data were obtained.Results: Neither absolute accuracy of estimation of duration of interview nor its transformed logarithm were significantly different between PWD and PWoutD, or between DAT and VaD participants. MDD participants performed significantly poorer than normal and did not differ from PWD, and the PWD relatively better performing subgroup. The logarithm of absolute accuracy of estimation correlated with some clinical and cognitive variables. Only a measure of depression and of impaired judgment could significantly predict it.Conclusions: The absolute accuracy of estimation of time-intervals did not differ between the major groups and the main diagnoses subgroups. It was associated with a variety of clinical and cognitive measures, and was predicted by the composite constructs of depression and impaired judgment. The diagnostic value of this measure in the psychogeriatric clinic is questionable, and limited to “worried” well individuals.


1983 ◽  
Vol 57 (3) ◽  
pp. 911-918 ◽  
Author(s):  
Lennart Tysk

Estimation of short time intervals by 60 healthy subjects, 50 patients with schizophrenic disorders, and 8 with schizotypal personality disorders, was investigated using the three different methods, adjusting a metronome, verbal estimation, and operative estimation (production). The schizophrenic patients tended to over-estimate time with all three methods. Over-estimation was also found when longer intervals were studied. Patients with different types of schizophrenic disorders, classified according to DSM-III criteria, over-estimated time about the same; no significant differences were found. Different courses of schizophrenia were also studied. Patients in remission over-estimated time to the same extent as chronic patients; the subchronic patients probably over-estimated less. Schizotypal personality disorders did not seem to be associated with a tendency to over-estimate short time intervals. The results were discussed in the context of perceptual disturbances in schizophrenic disorders.


2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Lidya R. Goni ◽  
Djon Wongkar ◽  
Sunny Wangko

Abstract: Morphologic changes of dead cells of an organ may be used as one of the alternatives to determine the time of death. Studies about macroscopic and microscopic postmortem changes in organs related to estimation of time of death are still limited. This study was aimed to obtain the macroscopic and microscopic changes of spleen based on the variation of time intervals up to 48 hours postmortem. This was a descriptive observational study that used two domestic pigs as animal model. The results showed that the macroscopic changes in the spleen occurred at 5 hours postmortem, characterized by changes in color and length. The spleen looked darker and became shorter (15 cm to 14.5 cm). At 30 hours postmortem, whitish spots appeared on the surface of the spleen. The earliest microscopic changes occured at 5 hours postmortem, characterized by congestion of Malpighian corpuscles. At 24 hours postmortem, a lot of cells in the Malpighian corpuscles showed pyknotic nuclei, and at 48 hours postmortem, most of the cells in the Malpighian corpuscles had undergone karyorrhexis and karyolisis. Conclusion: The earliest macroscopic changes occured at 5 hours postmortem meanwhile the earliest microscopic changes occured at 5 hours postmortem as congestion of Mapighian corpuscles. The lymphocytes inside the corpuscles showed pyknotic nuclei at 24 hours postmortem and became karyorrhexis as well as karyolysis at 48 hours postmortem.Keywords: macroscopic and microscopic description, spleen, postmortem Abstrak: Perubahan morfologi sel mati dari suatu organ dapat digunakan sebagai salah satu alternatif untuk menentukan lama waktu kematian. Penelitian mengenai perubahan makroskopik dan mikroskopik postmortem dari organ-organ sebagai alternatif perkiraan waktu kematian belum banyak dilakukan. Penelitian ini bertujuan untuk mendapatkan gambaran makroskopik dan mikroskopik limpa postmortem berdasarkan variasi waktu sampai 48 jam. Jenis penelitian ialah deskriptif observasional menggunakan dua ekor babi domestik sebagai hewan coba. Hasil penelitian menunjukkan perubahan makroskopik limpa pada hewan coba mulai tampak pada 5 jam postmortem ditandai dengan perubahan warna dan panjang limpa. Limpa tampak lebih gelap dan menjadi lebih pendek (15 cm menjadi 14,5 cm). Pada 42 jam postmortem muncul bercak-bercak pucat pada permukaan limpa. Perubahan mikroskopik limpa mulai tampak pada 5 jam postmortem yang ditandai dengan kongesti korpus Malpighi. Pada 24 jam postmortem sebagian besar limfosit dalam korpus memperlihatkan inti piknotik yang menjadi karioreksis dan kariolisis pada 48 jam postmortem. Kata kunci: gambaran makroskopik dan mikroskopik, limpa, postmortem


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