scholarly journals Histochemical studies of human breast cancer using a monoclonal antibody against an oestrogen receptor-related antigen

1987 ◽  
Vol 55 (6) ◽  
pp. 611-616
Author(s):  
RA Hawkins ◽  
K Sangster ◽  
A Krajewski
Keyword(s):  
Breast Cancer ◽  
Monoclonal Antibody ◽  
Human Breast Cancer ◽  
Oestrogen Receptor ◽  
Human Breast

scholarly journals Oestrogen receptors and antioestrogen treatment of hormone-dependent tumours

2018 ◽  
Vol 49 (2) ◽  
pp. 91
Author(s):  
N. G. KOSTOMITSOPOULOS (Ν.Γ. ΚΩΣΤΟΜΗΤΣΟΠΟΥΛΟΣ)
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Dna Sequences ◽  
Human Breast Cancer ◽  
Oestrogen Receptor ◽  
Specific Gene ◽  
Oestrogen Receptors ◽  
Human Breast ◽  
Potential Use

The oestrogen receptor is a ligand-activated transcription factor that modulates specific gene expression by binding to short DNA sequences. The study of the role of oestrogen receptor on the expression of the mitogenic actionof oestrogens and oncogenesis lead biomedical research in new approaches of the treatment of oestrogen-dependent tumors by using antioestrogens. Main mechanism of action of antioestrogens is the prevention of oestrogen action by blocking the binding of oestradiol to the oestrogen receptor. Tamoxifen, the most wellknown antioestrogen, is widely used as adjuvant therapy in all stages of human breast cancer. Recently interest is focused on the potential use of "pure" antioestrogens. The use of antioestrogens in veterinary oncology is also under discussion.

Interactions between MAP kinase and oestrogen receptor in human breast cancer

2013 ◽  
Vol 49 (6) ◽  
pp. 1176-1186 ◽  
Author(s):  
Liane M. McGlynn ◽  
Sian Tovey ◽  
John M.S. Bartlett ◽  
Julie Doughty ◽  
Timothy G. Cooke ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Map Kinase ◽  
Human Breast Cancer ◽  
Oestrogen Receptor ◽  
Human Breast

Modulation of Bcl-2 and Ki-67 expression in oestrogen receptor-positive human breast cancer by tamoxifen

1994 ◽  
Vol 30 (11) ◽  
pp. 1663-1669 ◽  
Author(s):  
S.R.D. Johnston ◽  
K.A. MacLennan ◽  
N.P.M. Sacks ◽  
J. Salter ◽  
I.E. Smith ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Human Breast Cancer ◽  
Oestrogen Receptor ◽  
Human Breast ◽  
Ki 67

The clinical relevance of oestrogen receptor binding to oligo(dT)—cellulose in human breast cancer

1986 ◽  
Vol 14 (5) ◽  
pp. 961-962
Author(s):  
GIRISH PARMAR ◽  
KATHRYN A. PHILIPSON ◽  
MICHAEL HERSHMAN ◽  
MURDOCH G. ELDER ◽  
CHRISTOPHER B. WOOD ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Receptor Binding ◽  
Clinical Relevance ◽  
Human Breast Cancer ◽  
Oestrogen Receptor ◽  
Human Breast
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