Progressive ocular inflammation following anti-tubercular therapy for presumed ocular tuberculosis in a high-endemic setting

Introduction: The ophthalmological manifestation of tuberculosis varies significantly, and almost all the elements of the globe and orbit can be reached. Methods and Results: The aim of this work was to report a clinical aspect of ocular tuberculosis in a young woman who has a notion of tuberculous contagion and who was presented at the fundus of a macular papillary membrane with a tubercle of Bouchut or papillary tubercle. The diagnosis was retained on a bundle of clinical, biological, and radiological arguments. The evolution under treatment was favorable with an improvement of its visual acuity. Conclusion: It is necessary to know how to evoke the tuberculous etiology in view of all ocular inflammation, even atypical. This is required considering the great polymorphism of its clinical characteristics.

Download Full-text

A case series of symptomatic ocular tuberculosis and the response to anti-tubercular therapy

Ceylon Medical Journal ◽

10.4038/cmj.v55i1.1703 ◽

2010 ◽

Vol 55 (1) ◽

pp. 16 ◽

Cited By ~ 6

Author(s):

BMGD Yasaratne ◽

D Madegedara ◽

NS Senanayake ◽

T Senaratne

Keyword(s):

Case Series ◽

Ocular Tuberculosis ◽

Anti Tubercular Therapy

Download Full-text

Combined Optic Neuropathy and Central Retinal Artery Occlusion in Presumed Ocular Tuberculosis without Detectable Systemic Infection

Ocular Immunology and Inflammation ◽

10.3109/09273948.2011.594203 ◽

2011 ◽

Vol 19 (5) ◽

pp. 370-372 ◽

Cited By ~ 5

Author(s):

Y. L. Ooi ◽

L. Y. Tai ◽

V. Subrayan ◽

I. Tajunisah

Keyword(s):

Optic Neuropathy ◽

Central Retinal Artery Occlusion ◽

Systemic Infection ◽

Retinal Artery Occlusion ◽

Artery Occlusion ◽

Central Retinal Artery ◽

Ocular Tuberculosis ◽

Retinal Artery ◽

Presumed Ocular Tuberculosis

Download Full-text

Review of Results of QuantiFERON TB Gold Test in Presumed Ocular Tuberculosis in a South Indian Patient Population

Ocular Immunology and Inflammation ◽

10.3109/09273948.2015.1010094 ◽

2015 ◽

pp. 1-5 ◽

Cited By ~ 3

Author(s):

Kalpana Babu ◽

Soumya S. Bhat ◽

Mariamma Philips ◽

D. K. Subbakrishna

Keyword(s):

Patient Population ◽

Indian Patient ◽

Ocular Tuberculosis ◽

South Indian ◽

Presumed Ocular Tuberculosis

Download Full-text

Clinical features and management of presumed ocular tuberculosis: A long-term follow-up cohort study in a tertiary referral center in Brazil

European Journal of Ophthalmology ◽

10.1177/11206721211044624 ◽

2021 ◽

pp. 112067212110446

Author(s):

Yuslay Fernández Zamora ◽

Luciana Peixoto Finamor ◽

Luci Meire P Silva ◽

Denise S Rodrigues ◽

Ricardo P Casaroli-Marano ◽

...

Keyword(s):

Clinical Features ◽

Oral Prednisone ◽

Interferon Gamma Release Assay ◽

Tertiary Referral ◽

Ocular Tuberculosis ◽

Tertiary Referral Center ◽

Referral Center ◽

Significant Difference ◽

Presumed Ocular Tuberculosis

Purpose: To evaluate the clinical features and management of presumed ocular tuberculosis (OTB). Method: A prospective 3-year follow-up study of patients with ocular inflammation that performed Interferon-gamma release assay (IGRA) and tuberculin skin test (TST) was conducted in a tertiary referral center in Brazil. Patients with clinical signs highly suspect of OTB with a positive TST and/or IGRA with other causes ruled out were prescribed anti-tuberculosis therapy (ATT) during 9 months. Clinical features and treatment outcomes were recorded. Results: Seventy-two patients (mean age 48.3 ± 15.7 years) were included in the study, and most were female (65.3%, n = 47). Posterior uveitis (43.1%, n = 31) was the main clinical feature. Multifocal choroiditis (25%, n = 18) was the most common choroidal involvement. Concomitant oral prednisone (45.8%, n = 33) during ATT was associated with more recurrences ( p = 0.04). A significant difference ( p < 0.001) between initial and final best-corrected visual acuity after ATT conclusion was observed. Cure or remission was observed in 58 (85.3%) patients that completed follow-up ( n = 68). Conclusion: In our cohort some variation in demographics and ocular phenotypes of presumed OTB was observed. The high rates of cure or remission of our patients strongly support the ATT in presumed OTB. Oral corticosteroids during ATT were associated with higher recurrences rates.

Download Full-text